scholarly journals Accelerated Fractionation Plus Chemotherapy Versus Conventionally Fractionated Radiochemotherapy for Unresectable Head-and-Neck Cancer

2021 ◽  
Vol 41 (2) ◽  
pp. 877-884
Author(s):  
DIRK RADES ◽  
CARLOS A. NARVAEZ ◽  
STEFAN JANSSEN ◽  
URSULA SCHRÖDER ◽  
KARL L. BRUCHHAGE ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Accelerated Fractionation ◽  
Conventionally Fractionated

Randomized Trials on Altered Fractionation in Head and Neck Cancer Radiotherapy with Conventional Fractionation as Control Arm: Another Lap to Go

1998 ◽  
Vol 84 (2) ◽  
pp. 160-166 ◽  
Author(s):  
Patrizia Olmi ◽  
Carlo Fallai
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Randomized Trials ◽  
Local Control Rate ◽  
Cancer Radiotherapy ◽  
Conventional Radiotherapy ◽  
Conventional Fractionation ◽  
Altered Fractionation ◽  
Accelerated Fractionation

The Authors present a review of randomized trials on non conventional fractionation in head and neck cancer radiotherapy with conventional fractionation as control arm. Hyperfractionation was studied in 5 trials, accelerated hyperfractionation in 4 trials and accelerated fractionation in 3 trials. Furthermore, the reviews of eminent Authors dealing with the above mentioned trials are summarized. In spite of improved local control rate reported with hyperfractionation, non conventional radiotherapy schedules are not yet recommended as routine clinical practice, but all the radiation oncologists are invited to join trials on this subject.

Nonstandard Fractionation Schedules in Radiation Therapy of Head and Neck Cancer: A Review

1997 ◽  
Vol 83 (3) ◽  
pp. 633-642 ◽  
Author(s):  
Patrizia Olmi ◽  
Carlo Fallai
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Late Toxicity ◽  
Research Field ◽  
Current Status ◽  
Introductory Overview ◽  
Accelerated Fractionation ◽  
Fractionation Schedules ◽  
Standard Fractionation

The authors present an updated review of the clinical trials on hyperfractionated and accelerated fractionation schedules in radiotherapy of head and neck cancer. The available results in terms of survival and local control, and acute and late toxicity data are summarized in order to show the current status of this research field. The new breed of fractionation schedules that are on study, designed on the ground of new rationales, are presented as well. Finally, an introductory overview of combination therapy including non standard fractionation radiotherapy associated with chemotherapy is reported70.

scholarly journals Accelerated fractionation radiotherapy and concomitant chemotherapy in patients with stage IV inoperable head and neck cancer

Cancer ◽  
1995 ◽  
Vol 76 (9) ◽  
pp. 1655-1661 ◽  
Author(s):  
Jadranka Dragovic ◽  
Thomas J. Doyle ◽  
Eugene J. Tilchen ◽  
Richard D. Nichols ◽  
Michael S. Benninger ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Stage Iv ◽  
Concomitant Chemotherapy ◽  
Accelerated Fractionation
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