Treatment Strategy for Rectal Cancer Patients With Inguinal Lymph Node Metastasis

2019 ◽  
Vol 39 (10) ◽  
pp. 5767-5772
Author(s):  
KOJI UETA ◽  
TAKERU MATSUDA ◽  
KIMIHIRO YAMASHITA ◽  
HIROSHI HASEGAWA ◽  
JUNKO MUKOHYAMA ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Cancer Patients ◽  
Treatment Strategy ◽  
Inguinal Lymph Node ◽  
Inguinal Lymph Node Metastasis ◽  
Node Metastasis

scholarly journals Risk factors and therapeutic significance for inguinal lymph node metastasis in advanced lower rectal cancer.

2019 ◽  
Vol 5 (suppl) ◽  
pp. 120-120
Author(s):  
Hiroaki Nozawa ◽  
Hiroshi Shiratori ◽  
Kazushige Kawai ◽  
Keisuke Hata ◽  
Toshiaki Tanaka ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Anal Canal ◽  
Inguinal Lymph Node ◽  
Dentate Line ◽  
Lower Rectal Cancer ◽  
Inguinal Lymph Node Metastasis ◽  
Node Metastasis ◽  
Therapeutic Value

120 Background: Which patients with lower rectal cancer are at risk of inguinal lymph node metastasis (ILNM) and how to treat ILNM remain unclear. This study aimed to clarify the predictors of ILNM and clinical significance of treatment for ILNM. Methods: Consecutive patients with rectal adenocarcinoma invading the anal canal who underwent curative surgery between 2003 and 2019 at a single institution were retrospectively reviewed. The pathological nodal involvement in mesorectal, lateral pelvic or inguinal lymph nodes (ILN) at the time of rectal surgery and of later onset were collectively defined as final nodal metastasis (f-LNM) in this study. Factors associated with f-LNM were analyzed. Moreover, the ‘modified therapeutic value index’ defined by the 5-year overall survival rate of patients treated against f-LNM multiplied by their frequency was calculated for each lymph node area. Results: A total of 145 patients were enrolled, among whom16 patients developed ILNM. For predicting f-ILNM, the cutoff 8.5 mm of ILN diameter gave area under the curve of 0.889. Dentate line involvement and ILN larger than a simplified cutoff of 8 mm were independently associated with the development of ILNM (odds ratio: 33.4 and 11.9, respectively). The modified therapeutic value indice of inguinal, lateral pelvic and mesorectal LNs in the entire population were 6.1, 8.2 and 20.3 points, respectively. In patients with dentate line invaded by cancer, they were 11.7, 5.8 and 16.2 points, respectively. Moreover, the index of ILN was 21.1 points when confined to patients with ILN larger than 8 mm. Conclusions: Dentate line involvement and ILN larger than 8 mm were predictive of developing ILNM in patients with rectal cancer invading the anal canal. Treatment of ILNM may be recommended for patients manifesting the above predictors, given the significant therapeutic outcomes.

Risk factors and therapeutic significance of inguinal lymph node metastasis in advanced lower rectal cancer

2020 ◽  
Vol 35 (4) ◽  
pp. 655-664 ◽  
Author(s):  
Hiroshi Shiratori ◽  
Hiroaki Nozawa ◽  
Kazushige Kawai ◽  
Keisuke Hata ◽  
Toshiaki Tanaka ◽  
...  
Keyword(s):  
Risk Factors ◽  
Rectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Inguinal Lymph Node ◽  
Lower Rectal Cancer ◽  
Inguinal Lymph Node Metastasis ◽  
Node Metastasis

Inguinal lymph node metastasis from contralateral testicular origin

Urology ◽  
1993 ◽  
Vol 41 (3) ◽  
pp. 275-277 ◽  
Author(s):  
Kenji Nishimoto ◽  
Hiroshi Ono ◽  
Masaaki Hirayama ◽  
Yukihisa Kadomoto ◽  
Tsuguru Usui
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Inguinal Lymph Node ◽  
Inguinal Lymph Node Metastasis ◽  
Node Metastasis

Pelvic lymph node status prediction in melanoma patients with inguinal lymph node metastasis

2014 ◽  
Vol 24 (5) ◽  
pp. 462-467 ◽  
Author(s):  
Sandro Pasquali ◽  
Simone Mocellin ◽  
Francesco Bigolin ◽  
Antonella Vecchiato ◽  
Maria C. Montesco ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Inguinal Lymph Node ◽  
Pelvic Lymph Node ◽  
Lymph Node Status ◽  
Inguinal Lymph Node Metastasis ◽  
Node Metastasis ◽  
Node Status ◽  
Melanoma Patients
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