scholarly journals Prediction of Portal Vein Thrombosis Following Hepatectomy for Perihilar Cholangiocarcinoma: Efficacy of Postoperative Portal Vein Diameter Ratio and Angle

2019 ◽  
Vol 39 (9) ◽  
pp. 5019-5026 ◽  
Author(s):  
TSUNEYUKI UCHIDA ◽  
YUSUKE YAMAMOTO ◽  
TEIICHI SUGIURA ◽  
YUKIYASU OKAMURA ◽  
TAKAAKI ITO ◽  
...  
HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S91
Author(s):  
M.T. Cao ◽  
R. Higuchi ◽  
T. Yazawa ◽  
S. Uemura ◽  
W. Izumo ◽  
...  

2020 ◽  
Author(s):  
Gang Dong ◽  
Xiaoquan Huang ◽  
Yuli Zhu ◽  
Hong Ding ◽  
Feng Li ◽  
...  

Abstract Background: Cirrhotic patients with portal vein thrombosis (PVT) may have a high risk of hepatic decompensation and increased mortality. This study aimed to investigate if increased portal vein diameter is associated with PVT development.Methods: A total of 174 cirrhotic patients were enrolled between February 1 and August 31, 2017. All participants were divided into PVT (n=62) and non-PVT (n=112) groups based on the thrombus that was detected by ultrasonography and confirmed by computed tomography angiography (CTA).Results: The study participants, aged 54.7±10.5 years (PVT) and 55.8±11.6 years (non‑PVT), were included in this analysis. The Child-Pugh score of PVT or non‑PVT was 6.6±1.3 and 5.8±0.9, respectively. Hepatitis B virus (HBV) is the primary etiological agent of cirrhosis. Logistic regression, receiver operating characteristic (ROC), and nomograph analysis designated portal diameter as the strongest independent risk factor for predicting PVT development (odds ratio (OR): 3.96, area under the ROC curve (AUC): 0.88;P<0.01), and the cutoff with predictive value for PVT development was >12.5 mm. No differences were observed in the overall survival (OS) in cirrhosis with or without PVT or stratifying on portal diameter based on the cutoff value.Conclusions: Increased portal diameter is associated with an increased risk of PVT development. Patients with cirrhosis and increased portal diameter are a high-risk subgroup that may need thromboprophylaxis.


BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guillaume Péré ◽  
Hubert Basselerie ◽  
Charlotte Maulat ◽  
Armando Pitocco ◽  
Pierrick Leblanc ◽  
...  

Abstract Background Portal vein thrombosis (PVT) is a common complication following splenectomy. It affects between 5 and 55% of patients undergoing surgery with no clearly defined pre-operative risk factors. The aim of this study was to determine the pre-operative risk factors of PVT. Patients and method Single centre, retrospective study of data compiled for every consecutive patient who underwent splenectomy at Toulouse University Hospital between January 2009 and January 2019. Patients with pre- and post-surgical CT scans have been included. Results 149 out of 261 patients were enrolled in the study (59% were males, mean age 52 years). The indications for splenectomy were splenic trauma (30.9%), malignant haemopathy (26.8%) and immune thrombocytopenia (8.0%). Twenty-nine cases of PVT (19.5%) were diagnosed based on a post-operative CT scan performed on post-operative day (POD) 5. Univariate analysis identifies three main risk factors associated with post-operative PVT: estimated splenic weight exceeding 500 g with an OR of 8.72 95% CI (3.3–22.9), splenic vein diameter over 10 mm with an OR of 4.92 95% CI (2.1–11.8) and lymphoma with an OR of 7.39 (2.7–20.1). The role of splenic vein diameter with an OR of 3.03 95% CI (1.1–8.6), and splenic weight with an OR of 5.22 (1.8–15.2), as independent risk factors is confirmed by multivariate analysis. A screening test based on a POD 5 CT scan with one or two of these items present could indicate sensitivity of 86.2% and specificity of 86.7%. Conclusion This study suggests that pre-operative CT scan findings could predict post-operative PVT. A CT scan should be performed on POD 5 if a risk factor has been identified prior to surgery.


2021 ◽  
Vol 9 (4) ◽  
pp. 289-289
Author(s):  
Gang Dong ◽  
Xiao-Quan Huang ◽  
Yu-Li Zhu ◽  
Hong Ding ◽  
Feng Li ◽  
...  

2017 ◽  
Vol 55 (05) ◽  
pp. e28-e56
Author(s):  
B Scheiner ◽  
P Stammet ◽  
S Pokorny ◽  
T Bucsics ◽  
P Schwabl ◽  
...  

1985 ◽  
Vol 54 (03) ◽  
pp. 724-724 ◽  
Author(s):  
Géza Sas ◽  
György Blaskó ◽  
Iván Petrö ◽  
John H Griffin

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