scholarly journals 7,8-Dihydroxy-3-arylcoumarin Induces Cell Death Through S-Phase Arrest in MDA-MB-231 Breast Cancer Cells

2018 ◽  
Vol 38 (11) ◽  
pp. 6091-6098 ◽  
Author(s):  
MUSILIYU A. MUSA ◽  
VEERA L. D. BADISA ◽  
LEKAN M. LATINWO ◽  
ELIZABETH NTANTIE
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
S Phase ◽  
Phase Arrest ◽  
S Phase Arrest

TCH-1030 targeting on topoisomerase I induces S-phase arrest, DNA fragmentation, and cell death of breast cancer cells

2013 ◽  
Vol 138 (2) ◽  
pp. 383-393 ◽  
Author(s):  
Yu-Peng Liu ◽  
Hui-Ling Chen ◽  
Cherng-Chyi Tzeng ◽  
Pei-Jung Lu ◽  
Cheng-Wei Lo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Dna Fragmentation ◽  
Topoisomerase I ◽  
Breast Cancer Cells ◽  
S Phase ◽  
Phase Arrest ◽  
S Phase Arrest

scholarly journals Gallotannin Imposes S Phase Arrest in Breast Cancer Cells and Suppresses the Growth of Triple-Negative Tumors In Vivo

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92853 ◽  
Author(s):  
Tiejun Zhao ◽  
Qiang Sun ◽  
Sonia V. del Rincon ◽  
Amanda Lovato ◽  
Maud Marques ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
S Phase ◽  
Phase Arrest ◽  
S Phase Arrest

Penta-1,2,3,4,6-O -galloyl-beta-D -glucose induces senescence-like terminal S-phase arrest in human hepatoma and breast cancer cells

2011 ◽  
Vol 50 (8) ◽  
pp. 592-600 ◽  
Author(s):  
Shutao Yin ◽  
Yinhui Dong ◽  
Jinhua Li ◽  
Junxuan Lü ◽  
Hongbo Hu
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
S Phase ◽  
Human Hepatoma ◽  
Phase Arrest ◽  
S Phase Arrest

scholarly journals Ultrasmall Fe3O4 nanoparticles induce S-phase arrest and inhibit cancer cells proliferation

2020 ◽  
Vol 9 (1) ◽  
pp. 61-69
Author(s):  
Ping Ye ◽  
Yuanyuan Ye ◽  
Xiaojing Chen ◽  
Hanbing Zou ◽  
Yan Zhou ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Breast Cancer Cells ◽  
S Phase ◽  
Therapeutic Drug ◽  
Ros Production ◽  
Phase Arrest ◽  
S Phase Arrest ◽  
Physicochemical Features ◽  
Cytotoxicity Effects ◽  
Ultrasmall Nanoparticles

AbstractThe ultrasmall nanoparticles easily lead to a more seriously response than larger nanoparticles because of their physicochemical features. It is essential to understand their cytotoxicity effects for their further application. Here, we used ultrasmall 9 nm Fe3O4 NPs to explore its cytotoxicity mechanism on breast cancer cells. We demonstrated 9 nm Fe3O4 NPswas effectively internalized into cells and located in nucleus, subsequently, it inhibited DNA synthesis through inducing S-phase arrest.Moreover, 9 nm Fe3O4 NPs induced ROS production and oxidative damage by disturbing the expression of antioxidant-related genes (HMOX-1, GCLC and GCLM), which resulted in the enhancement of cells apoptosis and inhibition of cell proliferation, suggesting its potential to be used as therapeutic drug.

Oxyresveratrol drives caspase-independent apoptosis-like cell death in MDA-MB-231 breast cancer cells through the induction of ROS

2020 ◽  
Vol 173 ◽  
pp. 113724 ◽  
Author(s):  
Damu Sunilkumar ◽  
G. Drishya ◽  
Aneesh Chandrasekharan ◽  
Sanu K. Shaji ◽  
Chinchu Bose ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Death ◽  
Cancer Cells ◽  
Breast Cancer Cells
Sign in / Sign up

Export Citation Format

Share Document