scholarly journals Establishment and Characterization of a Novel Human Clear-cell Sarcoma of Soft-tissue Cell Line, RSAR001, Derived from Pleural Effusion of a Patient with Pleural Dissemination

2018 ◽  
Vol 38 (9) ◽  
pp. 5035-5042
Author(s):  
MICHIYUKI HAKOZAKI ◽  
HIROSUMI TAMURA ◽  
YUU DOBASHI ◽  
AKI YOSHIDA ◽  
KOUKI KATO ◽  
...  
Keyword(s):  
Pleural Effusion ◽  
Soft Tissue ◽  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Tissue Cell ◽  
Cell Sarcoma ◽  
Pleural Dissemination

Establishment and characterization of a new human clear-cell sarcoma cell-line, HS-MM

1993 ◽  
Vol 169 (3) ◽  
pp. 317-322 ◽  
Author(s):  
Hiroshi Sonobe ◽  
Mutsuo Furihata ◽  
Jun Iwata ◽  
Yuji Ohtsuki ◽  
Hiroo Mizobuchi ◽  
...  
Keyword(s):  
Cell Line ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Sarcoma Cell ◽  
Sarcoma Cell Line ◽  
Cell Sarcoma

scholarly journals Expression Profiling of t(12;22) Positive Clear Cell Sarcoma of Soft Tissue Cell Lines Reveals Characteristic Up-Regulation of Potential New Marker Genes Including ERBB3

2004 ◽  
Vol 64 (10) ◽  
pp. 3395-3405 ◽  
Author(s):  
Karl-Ludwig Schaefer ◽  
Kristin Brachwitz ◽  
Daniel H. Wai ◽  
Yvonne Braun ◽  
Raihanatou Diallo ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cell Lines ◽  
Expression Profiling ◽  
Clear Cell ◽  
Clear Cell Sarcoma ◽  
Marker Genes ◽  
Tissue Cell ◽  
Cell Sarcoma

scholarly journals The Therapeutic Approach of Soft – Tissue Sarcomas. A 12 Cases Analysis

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 58
Author(s):  
V. Georgeanu ◽  
T. Atasiei ◽  
D. Gartonea ◽  
B. Shazam ◽  
G. Goleşteanu ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Synovial Sarcoma ◽  
Therapeutic Approach ◽  
Clear Cell ◽  
Postoperative Radiotherapy ◽  
Soft Tissue Sarcomas ◽  
Clear Cell Sarcoma ◽  
Cell Sarcoma ◽  
Special Cases

Abstract Introduction. Soft Tissue Sarcomas (STS) is a group of rare malignant tumors with mesenchymal tissue origin. At present, over 50 histopathological types with typical chromosome changes are described. Treatment is multidisciplinary, centered on the surgical approach. Method. Between 2014 and 2016, 12 STS cases were treated in our clinic: 3 liposarcomas, 2 synovial sarcomas, 1 angiosarcoma, 2 rhabdomyosarcomas, 2 myxofibrosarcomas, 1 fibroblast sarcoma and 1 clear cell sarcoma. With the exception of angiosarcoma that benefited only from chemotherapy, the other cases were surgically approached, followed by radiotherapy in 7 cases, and chemotherapy in one case. Results. Patient follow-up was for a minimum of 2 years. In 3 cases (fibroblast sarcoma, clear-cell sarcoma, synovial sarcoma), a local recurrence occurred between 3 and 9 months. In 2 cases (fibroblastic sarcoma, synovial sarcoma), pulmonary metastases occurred between 6 and 18 months and the patients died at 8 months and 2 years respectively. The rest of the cases were clinically and imagistically assessed (local MRI, lung CT) at 6 months for at least 2 years and showed no signs of local recurrence or metastasis. Conclusions. The evolution of STS depends on the histological type and to the stage of diagnosis (local extension, degree of differentiation and presence of metastases). Therapeutic approach should be centered on an accurate resection, within the limits of oncological safety even with re-resection. Postoperative radiotherapy is used in most of the cases, and chemotherapy is reserved for special cases with unfavorable local evolution or metastasis.

Lymphotropic Sarcomas (Epithelioid Sarcoma and Clear Cell Sarcoma)

2019 ◽  
Author(s):  
Alexandra G Lopez-Aguiar ◽  
Kenneth Cardona
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Soft Tissue ◽  
Clear Cell ◽  
Epithelioid Sarcoma ◽  
Clear Cell Sarcoma ◽  
Lymph Node Biopsy ◽  
Cell Sarcoma ◽  
Node Biopsy

Lymphotropic sarcomas encompass a rare subset of soft tissue sarcoma histotypes known for their distinct ability to metastasize to locoregional lymph nodes. Epithelioid and clear cell sarcomas are the predominant lymphotropic subtypes and the focus of this review. The utility of lymph node assessment, whether clinical, radiographic, and/or surgical, in patients with these sarcomas is presented. The role of sentinel lymph node biopsy as well as completion lymphadenectomy in patients with these lymphotropic sarcoma histotypes is discussed. Surgery remains the only potential curative option for these tumors, and advancement in histology-specific chemotherapeutic regimens and biologic therapy options is necessary.  This review contains 6 tables and 50 references. Key words: clear cell sarcoma, completion lymphadenectomy, epithelioid sarcoma, EWS-ATF1, limb-sparing surgery, lymph node metastasis, sentinel lymph node biopsy, soft tissue sarcoma

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