scholarly journals Predicting the Risk of Developing New Cerebral Lesions After Stereotactic Radiosurgery or Fractionated Stereotactic Radiotherapy for Brain Metastases from Renal Cell Carcinoma

2018 ◽  
Vol 38 (5) ◽  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Stereotactic Radiotherapy ◽  
Renal Cell ◽  
Fractionated Stereotactic Radiotherapy ◽  
Cerebral Lesions

Fractionated stereotactic radiotherapy of brain metastases from renal cell carcinoma

2000 ◽  
Vol 48 (5) ◽  
pp. 1389-1393 ◽  
Author(s):  
Hitoshi Ikushima ◽  
Koichi Tokuuye ◽  
Minako Sumi ◽  
Yoshikazu Kagami ◽  
Shigeyuki Murayama ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiotherapy ◽  
Renal Cell ◽  
Fractionated Stereotactic Radiotherapy

Pathologic Complete Response in Renal Cell Carcinoma Brain Metastases Treated with Stereotactic Radiosurgery

2007 ◽  
Vol 5 (5) ◽  
pp. 334-337 ◽  
Author(s):  
Bin S. Teh ◽  
Charles Bloch ◽  
Arnold C. Paulino ◽  
Steven Shen ◽  
Lisa Hinckley ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Renal Cell ◽  
Pathologic Complete Response ◽  
Complete Response

Outcome Predictors of Gamma Knife Radiosurgery for Renal Cell Carcinoma Metastases

Neurosurgery ◽  
2011 ◽  
Vol 69 (6) ◽  
pp. 1232-1239 ◽  
Author(s):  
Hideyuki Kano ◽  
Aditya Iyer ◽  
Douglas Kondziolka ◽  
Ajay Niranjan ◽  
John C. Flickinger ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Median Survival ◽  
Renal Cell ◽  
Karnofsky Performance Status ◽  
Performance Status ◽  
Gamma Knife Radiosurgery ◽  
Tumor Control

Abstract BACKGROUND Although whole-brain radiation therapy (WBRT) has been a standard palliative management for brain metastases from renal cell carcinoma, its benefit has been elusive because of radiobiological resistance. OBJECTIVE To evaluate the role of stereotactic radiosurgery (SRS) in the management of brain metastases from renal cell carcinoma. METHODS We reviewed records from 158 consecutive patients (men = 111, women = 47) who underwent SRS for 531 brain metastases from renal cell carcinoma. The median patient age was 61 years (range, 38-83 years), and the median number of tumors per patient was 1 (range, 1–10). Seventy-nine patients (50%) had solitary brain metastasis. Fifty-seven patients (36%) underwent prior WBRT. The median total tumor volume for each patient was 3.0 cm3 (range, 0.09-47 cm3). RESULTS The overall survival after SRS was 60%, 38%, and 19% at 6, 12, and 24 months, respectively, with a median survival of 8.2 months. Factors associated with longer survival included younger age, longer interval between primary diagnosis and brain metastases, lower recursive partitioning analysis class, higher Karnofsky performance status, smaller number of brain metastases, and no prior WBRT. Median survival for patients with > 2 brain metastases, higher Karnofsky performance status (> 90), and no prior WBRT was 12 months after SRS. Sustained local tumor control was achieved in 92% of patients. Symptomatic adverse radiation effects occurred in 7%. Overall, 70% of patients improved or remained neurologically stable. CONCLUSION Stereotactic radiosurgery is an especially valuable option for patients with higher Karnofsky performance status and smaller number of brain metastases from renal cell carcinoma.

Outcomes of Stereotactic Radiosurgery and Immunotherapy in Renal Cell Carcinoma Patients With Brain Metastases

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Haruka Uezono ◽  
David Nam ◽  
Harriet M. Kluger ◽  
Mario Sznol ◽  
Michael Hurwitz ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Renal Cell

Stereotactic radiosurgery as single-modality treatment of incidentally identified renal cell carcinoma brain metastases

2010 ◽  
Vol 73 (3) ◽  
pp. 186-193 ◽  
Author(s):  
Nicholas F. Marko ◽  
Lilyana Angelov ◽  
Steven A. Toms ◽  
John H. Suh ◽  
Sam T. Chao ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Renal Cell ◽  
Single Modality

979 poster STEREOTACTIC RADIOSURGERY FOR THE TREATMENT OF MELANOMA AND RENAL CELL CARCINOMA BRAIN METASTASES

2011 ◽  
Vol 99 ◽  
pp. S370
Author(s):  
P. Goetz ◽  
S. Lwu ◽  
M. Aryaee ◽  
C. Menard ◽  
N.J. Laperriere ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Renal Cell

Utilization of Stereotactic Radiosurgery for Renal Cell Carcinoma Brain Metastases

2018 ◽  
Vol 16 (4) ◽  
pp. e935-e943 ◽  
Author(s):  
Waqar Haque ◽  
Vivek Verma ◽  
E.Brian Butler ◽  
Bin S. Teh
Keyword(s):  
Renal Cell Carcinoma ◽  
Brain Metastases ◽  
Cell Carcinoma ◽  
Stereotactic Radiosurgery ◽  
Renal Cell
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