scholarly journals Survival in Limited Disease Small Cell Lung Cancer According to N3 Lymph Node Involvement

2018 ◽  
Vol 38 (2) ◽  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Lymph Node Involvement ◽  
Small Cell ◽  
Small Cell Lung ◽  
Limited Disease ◽  
Node Involvement ◽  
N3 Lymph Node

Survival and characteristics of lymph node involvement in patients with N1 non-small cell lung cancer

Lung Cancer ◽  
2004 ◽  
Vol 43 (2) ◽  
pp. 151-157 ◽  
Author(s):  
Toshihiro Osaki ◽  
Akira Nagashima ◽  
Takashi Yoshimatsu ◽  
Yuko Tashima ◽  
Kosei Yasumoto
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Lymph Node Involvement ◽  
Small Cell ◽  
Small Cell Lung ◽  
Node Involvement

Survival of Patients With Resected N2 Non–Small-Cell Lung Cancer: Evidence for a Subclassification and Implications

2000 ◽  
Vol 18 (16) ◽  
pp. 2981-2989 ◽  
Author(s):  
Fabrice Andre ◽  
Dominique Grunenwald ◽  
Jean-Pierre Pignon ◽  
Antoine Dujon ◽  
Jean Louis Pujol ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Preoperative Chemotherapy ◽  
Cell Lung Cancer ◽  
Survival Rates ◽  
Lymph Node Involvement ◽  
Small Cell ◽  
Small Cell Lung ◽  
Node Involvement

PURPOSE: Patients who suffer from non–small-cell lung cancer (NSCLC) with ipsilateral mediastinal lymph node involvement (N2) belong to a heterogeneous subgroup of patients. We analyzed the prognosis of patients with resected N2 NSCLC to propose homogeneous patient subgroups.PATIENTS AND METHODS: The present study comprised 702 consecutive patients from six French centers who underwent surgical resection of N2 NSCLC. Initially, two groups of patients were defined: patients with clinical N2 (cN2) and those with minimal N2 (mN2) disease were patients in whom N2 disease was and was not detected preoperatively at computed tomographic scan, respectively.RESULTS: The median duration of follow-up was 52 months (range, 18 to 120 months). A multivariate analysis using Cox regression identified four negative prognostic factors, namely, cN2 status (P < .0001), involvement of multiple lymph node levels (L2+; P < .0001), pT3 to T4 stage (P < .0001), and no preoperative chemotherapy (P < .01). For patients treated with primary surgery, 5-year survival rates were as follows: mN2, one level involved (mN2L1, n = 244): 34%; mN2, multiple level involvement (mN2L2+, n = 78): 11%; cN2L1 (n = 118): 8%; and cN2L2+ (n = 122): 3%. When only patients with mN2L1 disease were considered, the site of lymph node involvement according to the American Thoracic Society numbering system had no prognostic significance (P = .14). Preoperative chemotherapy was associated with a better prognosis for those with cN2 (P < .0001). Five-year survival rates were 18% and 5% for cN2 patients treated with and without preoperative chemotherapy, respectively.CONCLUSION: This study has identified homogeneous N2 NSCLC prognostic subgroups and suggests different therapeutic approaches according to the subgroup profile.

Prognostic Significance of Surgical-Pathologic N1 Lymph Node Involvement in Non-Small Cell Lung Cancer

2009 ◽  
Vol 87 (4) ◽  
pp. 1014-1022 ◽  
Author(s):  
Adalet Demir ◽  
Akif Turna ◽  
Celalettin Kocaturk ◽  
Mehmet Zeki Gunluoglu ◽  
Umit Aydogmus ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Prognostic Significance ◽  
Lymph Node Involvement ◽  
Small Cell ◽  
Small Cell Lung ◽  
Node Involvement

Plasma D-dimer value as a predictor of malignant lymph node involvement in operable non-small cell lung cancer

Tumor Biology ◽  
2015 ◽  
Vol 36 (12) ◽  
pp. 9201-9207 ◽  
Author(s):  
Feng Chen ◽  
Min-Jie Wang ◽  
Jia Li ◽  
Cui-E Yan ◽  
Xiao-Hong Han ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Lymph Node ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Lymph Node Involvement ◽  
Small Cell ◽  
Small Cell Lung ◽  
Malignant Lymph Node ◽  
Node Involvement ◽  
D Dimer
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