scholarly journals Lessons from Sl-j/fmpt life science experiment. Health Monitoring of Japanese Payload Specialist During Space Flight.

1993 ◽  
Vol 7 (4) ◽  
pp. 303-309
Author(s):  
Chiharu SEKIGUCHI ◽  
Tadashi MURAI ◽  
Masanori ISHII ◽  
Kazuyoshi YAJIMA ◽  
Kiyoshi NAKAYAMA
2012 ◽  
Author(s):  
William Reiser ◽  
Brandon Runnels ◽  
Chris White ◽  
Abraham Light-Marquez ◽  
Andrei Zagrai ◽  
...  

Author(s):  
David Siler ◽  
Ben Cooper ◽  
Chris White ◽  
Stephen Marinsek ◽  
Andrei Zagrai ◽  
...  

The paper presents the design, development, and assembly of Structural Health Monitoring (SHM) experiments intended to be launch in space on a sub-orbital rocket flight as well as a high altitude balloon flight. The experiments designed investigate the use of both piezoelectric sensing hardware in a wave propagation experiment and piezoelectric wafer active sensors (PWAS) in an electromechanical impedance experiment as active elements of spacecraft SHM systems. The list of PWAS experiments includes a bolted-joint test and an experiment to monitor PWAS condition during spaceflight. Electromechanical impedances of piezoelectric sensors will be recorded in-flight at varying input frequencies using an onboard data acquisition system. The wave propagation experiment will utilize the sensing hardware of the Metis Design MD7 Digital SHM system. The payload will employ a triggering system that will begin experiment data acquisition upon sufficient saturation of g-loading. The experiment designs must be able to withstand the harsh environment of space, intense vibrations from the rocket launch, and large shock loading upon re-entry. The paper discusses issues encountered during design, development, and assembly of the payload and aspects central to successful demonstration of the SHM system during both the sub-orbital space flight and balloon launch.


2012 ◽  
Vol 132 (3) ◽  
pp. 1964-1964
Author(s):  
Andrei N. Zagrai ◽  
William Reiser ◽  
Brandon Runnels ◽  
Chris White ◽  
Abraham Light-Marquez ◽  
...  

Author(s):  
Walter J. Sapp ◽  
D.E. Philpott ◽  
C.S. Williams ◽  
K. Kato ◽  
J. Stevenson ◽  
...  

Space flight, with its unique environmental constraints such as immobilization, decreased and increased pressures, and radiation, is known to affect testicular morphology and spermatogenesis. Selye, summarized the manifestations of physiological response to nonspecific stress and he pointed out that atrophy of the gonads always occurred. Reports of data collected from two dogs flown in space for 22 days (Cosmos 110) indicate that there was an increase of 30 to 70% atypical spermatozoa when compared to ground based controls. Seventy-five days after the flight the abnormalities had decreased to the high normal value of 30% and mating of these dogs after this period produced normal offspring, suggesting complete recovery. Effects of immobilization and increased gravity were investigated by spinning rats and mice at 2x g for 8-9 weeks. A decrease in testicular weight was noted in spun animals when compared to controls. Immobilization has been show to cause arrest of spermatogenesis in Macaca meminstrins.


Author(s):  
Uwe Lücken ◽  
Michael Felsmann ◽  
Wim M. Busing ◽  
Frank de Jong

A new microscope for the study of life science specimen has been developed. Special attention has been given to the problems of unstained samples, cryo-specimens and x-ray analysis at low concentrations.A new objective lens with a Cs of 6.2 mm and a focal length of 5.9 mm for high-contrast imaging has been developed. The contrast of a TWIN lens (f = 2.8 mm, Cs = 2 mm) and the BioTWTN are compared at the level of mean and SD of slow scan CCD images. Figure 1a shows 500 +/- 150 and Fig. 1b only 500 +/- 40 counts/pixel. The contrast-forming mechanism for amplitude contrast is dependent on the wavelength, the objective aperture and the focal length. For similar image conditions (same voltage, same objective aperture) the BioTWIN shows more than double the contrast of the TWIN lens. For phasecontrast specimens (like thin frozen-hydrated films) the contrast at Scherzer focus is approximately proportional to the √ Cs.


Author(s):  
Judith M. Brock ◽  
Max T. Otten

A knowledge of the distribution of chemical elements in a specimen is often highly useful. In materials science specimens features such as grain boundaries and precipitates generally force a certain order on mental distribution, so that a single profile away from the boundary or precipitate gives a full description of all relevant data. No such simplicity can be assumed in life science specimens, where elements can occur various combinations and in different concentrations in tissue. In the latter case a two-dimensional elemental-distribution image is required to describe the material adequately. X-ray mapping provides such of the distribution of elements.The big disadvantage of x-ray mapping hitherto has been one requirement: the transmission electron microscope must have the scanning function. In cases where the STEM functionality – to record scanning images using a variety of STEM detectors – is not used, but only x-ray mapping is intended, a significant investment must still be made in the scanning system: electronics that drive the beam, detectors for generating the scanning images, and monitors for displaying and recording the images.


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