scholarly journals Hypergravity induces vertebrae and otolith deformation in medaka fish

2019 ◽  
Vol 33 (0) ◽  
pp. 12-17
Author(s):  
Masahiro Chatani ◽  
Aiko Mitsuhashi ◽  
Yusuke Dodo ◽  
Nobuhiro Sakai ◽  
Masamichi Takami
Keyword(s):  
Medaka Fish

Developmental and bone development indexes of medaka fish at 11 and 16 days of age

2018 ◽  
Vol 60 (4) ◽  
pp. 52-58 ◽  
Author(s):  
Thi Kieu Oanh Pham ◽  
Van Cuong Pham ◽  
Thi Thuy Lai ◽  
Duc Long Tran ◽  
Thanh Thuy To ◽  
...  
Keyword(s):  
Bone Development ◽  
Medaka Fish

Sex-Linked Inheritance of thelfLocus in the Medaka Fish (Oryzias latipes)

1998 ◽  
Vol 15 (1) ◽  
pp. 123-126 ◽  
Author(s):  
Hironori Wada ◽  
Atsuko Shimada ◽  
Shoji Fukamachi ◽  
Kiyoshi Naruse ◽  
Akihiro Shima
Keyword(s):  
Oryzias Latipes ◽  
Medaka Fish

Differentiation of nucleated erythrocytes using gata1 reporter medaka fish

2013 ◽  
Vol 41 (8) ◽  
pp. S25
Author(s):  
Shun Maekawa ◽  
Ayumi Hirano ◽  
Yuta Uchida ◽  
Shungo Konno ◽  
Sakiko Hosozawa ◽  
...  
Keyword(s):  
Medaka Fish

scholarly journals MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma

2015 ◽  
Vol 112 (25) ◽  
pp. E3236-E3245 ◽  
Author(s):  
Ivan Conte ◽  
Kristen D. Hadfield ◽  
Sara Barbato ◽  
Sabrina Carrella ◽  
Mariateresa Pizzo ◽  
...  
Keyword(s):  
Developmental Disorders ◽  
Retinal Pigment ◽  
Retinal Dystrophy ◽  
In Vitro Assays ◽  
Heterozygous Mutation ◽  
Seed Region ◽  
Medaka Fish ◽  
Inherited Retinal Dystrophies

Ocular developmental disorders, including the group classified as microphthalmia, anophthalmia, and coloboma (MAC) and inherited retinal dystrophies, collectively represent leading causes of hereditary blindness. Characterized by extreme genetic and clinical heterogeneity, the separate groups share many common genetic causes, in particular relating to pathways controlling retinal and retinal pigment epithelial maintenance. To understand these shared pathways and delineate the overlap between these groups, we investigated the genetic cause of an autosomal dominantly inherited condition of retinal dystrophy and bilateral coloboma, present in varying degrees in a large, five-generation family. By linkage analysis and exome sequencing, we identified a previously undescribed heterozygous mutation, n.37C > T, in the seed region of microRNA-204 (miR-204), which segregates with the disease in all affected individuals. We demonstrated that this mutation determines significant alterations of miR-204 targeting capabilities via in vitro assays, including transcriptome analysis. In vivo injection, in medaka fish (Oryzias latipes), of the mutated miR-204 caused a phenotype consistent with that observed in the family, including photoreceptor alterations with reduced numbers of both cones and rods as a result of increased apoptosis, thereby confirming the pathogenic effect of the n.37C > T mutation. Finally, knockdown assays in medaka fish demonstrated that miR-204 is necessary for normal photoreceptor function. Overall, these data highlight the importance of miR-204 in the regulation of ocular development and maintenance and provide the first evidence, to our knowledge, of its contribution to eye disease, likely through a gain-of-function mechanism.

DNA-based transposable elements with nucleotide sequence similar to Tol2 from medaka fish are prevalent in cyprinid fishes

Gene Reports ◽  
2017 ◽  
Vol 9 ◽  
pp. 37-45 ◽  
Author(s):  
Suzutaro Ishiyama ◽  
Kentaro Yamazaki ◽  
Fumiya Kurihara ◽  
Daisuke Yamashita ◽  
Kentaro Sao ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Transposable Elements ◽  
Medaka Fish ◽  
Cyprinid Fishes

scholarly journals Medaka Fish Parkinson's Disease Model

2012 ◽  
Vol 21 (3) ◽  
pp. 94-100 ◽  
Author(s):  
Hideaki Matsui ◽  
Roberto Gavinio ◽  
Ryosuke Takahashi
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Disease Model ◽  
Medaka Fish

Hox Gene Complexity in Medaka Fish May Be Similar to That in Pufferfish Rather Than Zebrafish

1999 ◽  
Vol 260 (1) ◽  
pp. 66-70 ◽  
Author(s):  
Gene Kurosawa ◽  
Kouji Yamada ◽  
Hiroshi Ishiguro ◽  
Hiroshi Hori
Keyword(s):  
Medaka Fish ◽  
Hox Gene
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