scholarly journals Virus shedding after H9N2 strain challenge of SPF Chickens immunized by an experimental Nano-Adjuvant and commercial oil emulsion avian influenza (H9N2) vaccines

2015 ◽  
Vol 9 (4) ◽  
pp. 18-23
Author(s):  
Zohreh Mojahedi ◽  
Mahdi Vasfi Marandi ◽  
Khosrow Aghaipour ◽  
Hamid Mahdavi ◽  
Seyed Ali Ppourbakhsh ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Virus Shedding ◽  
Oil Emulsion ◽  
Avian Influenza H9n2 ◽  
Commercial Oil

scholarly journals RETRACTED: Mycoplasma synoviae vaccine modifies virus shedding and immune responses of avian influenza (H9N2) infection in commercial layers

2017 ◽  
Vol 96 (9) ◽  
pp. 3086-3095 ◽  
Author(s):  
Sajid Umar ◽  
Muhammad Tanweer ◽  
Mudassar Iqbal ◽  
Asad Shahzad ◽  
Farooq Hassan ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Immune Responses ◽  
Mycoplasma Synoviae ◽  
Virus Shedding ◽  
Avian Influenza H9n2

scholarly journals Combined H5ND inactivated vaccine protects chickens against challenge by different clades of highly pathogenic avian influenza viruses subtype H5 and virulent Newcastle disease virus

2019 ◽  
Vol 12 (1) ◽  
pp. 97-105 ◽  
Author(s):  
Ahmed Ali ◽  
Marwa Safwat ◽  
Walid H. Kilany ◽  
Abdou Nagy ◽  
Awad A. Shehata ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Newcastle Disease ◽  
Highly Pathogenic Avian Influenza ◽  
Highly Pathogenic ◽  
Virus Shedding ◽  
Oil Emulsion ◽  
Pathogenic Avian Influenza ◽  
Clinical Protection ◽  
Hpai H5n1 ◽  
Antibody Titers

Aim: The aim of the current study was to evaluate the efficacy of a trivalent-inactivated oil-emulsion vaccine against challenge by different clades highly pathogenic avian influenza (HPAI) viruses including HPAI-H5N8 and the virulent genotype VII Newcastle disease virus (NDV) (vNDV). Materials and Methods: The vaccine studied herein is composed of reassortant AI viruses rgA/Chicken/Egypt/ ME1010/2016 (clade 2.2.1.1), H5N1 rgA/Chicken/Egypt/RG-173CAL/2017 (clade 2.2.1.2), and "NDV" (LaSota NDV/ CK/Egypt/11478AF/11); all used at a concentration of 108 EID50/bird and mixed with Montanide-ISA70 oil adjuvant. Two-week-old specific pathogen free (SPF) chickens were immunized subcutaneously with 0.5 ml of the vaccine, and hemagglutination inhibition (HI) antibody titers were monitored weekly. The intranasal challenge was conducted 4 weeks post-vaccination (PV) using 106 EID50/0.1 ml of the different virulent HPAI-H5N1 viruses representing clades 2.2.1, 2.2.1.1, 2.2.1.2, 2.3.4.4b-H5N8, and the vNDV. Results: The vaccine induced HI antibody titers of >6log2 against both H5N1 and NDV viruses at 2 weeks PV. Clinical protection against all HPAI H5N1 viruses and vNDV was 100%, except for HPAI H5N1 clade-2.2.1 and HPAI H5N8 clade- 2.3.4.4b viruses that showed 93.3% protection. Challenged SPF chickens showed significant decreases in the virus shedding titers up to <3log10 compared to challenge control chickens. No virus shedding was detected 6 "days post-challenge" in all vaccinated challenged groups. Conclusion: Our results indicate that the trivalent H5ND vaccine provides significant clinical protection against different clades of the HPAI viruses including the newly emerging H5N8 HPAI virus. Availability of such potent multivalent oil-emulsion vaccine offers an effective tool against HPAI control in endemic countries and promises simpler vaccination programs.

Vaccination with CpG-Adjuvanted Avian Influenza Virosomes Promotes Antiviral Immune Responses and Reduces Virus Shedding in Chickens

2012 ◽  
pp. 120418071632002 ◽  
Author(s):  
Amirul I. Mallick ◽  
Raveendra R. Kulkarni ◽  
Michael St. Paul ◽  
Payvand Parvizi ◽  
Éva Nagy ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Immune Responses ◽  
Virus Shedding

scholarly journals Insights into genetic diversity and biological propensities of potentially zoonotic avian influenza H9N2 viruses circulating in Egypt

Virology ◽  
2017 ◽  
Vol 511 ◽  
pp. 165-174 ◽  
Author(s):  
Mahmoud M. Naguib ◽  
Abdel-Satar Arafa ◽  
Rokshana Parvin ◽  
Martin Beer ◽  
Thomas Vahlenkamp ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Avian Influenza ◽  
Avian Influenza H9n2

scholarly journals Avian influenza H9N2 virus isolated from air samples in LPMs in Jiangxi, China

2017 ◽  
Vol 14 (1) ◽  
Author(s):  
Xiaoxu Zeng ◽  
Mingbin Liu ◽  
Heng Zhang ◽  
Jingwen Wu ◽  
Xiang Zhao ◽  
...  
Keyword(s):  
Avian Influenza ◽  
H9n2 Virus ◽  
Air Samples ◽  
Avian Influenza H9n2

scholarly journals Protection and Virus Shedding of Falcons Vaccinated against Highly Pathogenic Avian Influenza A Virus (H5N1)

2007 ◽  
Vol 13 (11) ◽  
pp. 1667-1674 ◽  
Author(s):  
Michael Lierz ◽  
Hafez M. Hafez ◽  
Robert Klopfleisch ◽  
Dörte Lüschow ◽  
Christine Prusas ◽  
...  
Keyword(s):  
Avian Influenza ◽  
Influenza A Virus ◽  
Influenza A ◽  
Highly Pathogenic Avian Influenza ◽  
Highly Pathogenic ◽  
Virus Shedding ◽  
Pathogenic Avian Influenza ◽  
Virus H5n1 ◽  
Avian Influenza A Virus
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