scholarly journals Aetiology, clinical presentation and current treatment options of equine malignant melanoma – a review of the literature

2014 ◽  
Vol 30 (4) ◽  
pp. 455-460 ◽  
Author(s):  
J M V Cavalleri ◽  
K Mählmann ◽  
P Steinig ◽  
K Feige
2012 ◽  
Vol 21 (3) ◽  
pp. 75-84
Author(s):  
Venkata Vijaya K. Dalai ◽  
Jason E. Childress ◽  
Paul E Schulz

Dementia is a major public health concern that afflicts an estimated 24.3 million people worldwide. Great strides are being made in order to better diagnose, prevent, and treat these disorders. Dementia is associated with multiple complications, some of which can be life-threatening, such as dysphagia. There is great variability between dementias in terms of when dysphagia and other swallowing disorders occur. In order to prepare the reader for the other articles in this publication discussing swallowing issues in depth, the authors of this article will provide a brief overview of the prevalence, risk factors, pathogenesis, clinical presentation, diagnosis, current treatment options, and implications for eating for the common forms of neurodegenerative dementias.


1992 ◽  
Vol 26 (11) ◽  
pp. 1452-1455 ◽  
Author(s):  
Jeffrey T. Moss ◽  
James P. Wilson

OBJECTIVE: To review the epidemiology, clinical presentation, risk factors for transmission, and pathogenesis of leishmaniasis, as well as current treatment options for this disease. DATA SOURCES/DATA SELECTION: We reviewed unclassified medical-threat briefing material, subject-matter reviews, and case reports from the world's infectious disease literature. We concentrated on literature pertaining to the pathogenesis and management of leishmaniasis indigenous to Southwest Asia. DATA EXTRACTION: Data from subject reviews published in the English language were evaluated. Case reports and clinical trials provided supplemental data on evolving theories and management options. DATA SYNTHESIS: The clinical presentation of leishmaniasis is highly variable. Management relies heavily upon the use of parenteral antimonial drugs. Although these agents are effective in most cases, toxicity and the emergence of resistance limit the usefulness of standard therapies. Alternative treatment modalities include heat, surgical curettage, ketoconazole, metronidazole, pentamidine, rifampin, amphotericin B, aminoglycosides, allopurinol, and immunotherapy. CONCLUSIONS: Although the number of reported cases of leishmaniasis in the US has generally been low, there is a possibility that more cases may be reported in the future because of the large number of military personnel returning to this country from endemic areas. Medical personnel, particularly those working in governmental institutions, should be familiar with the pathogenesis of this unusual infection as well as potential treatment options.


2016 ◽  
Vol 2016 ◽  
pp. 1-9
Author(s):  
Noemi Cantone ◽  
Caterina Gulia ◽  
Vittorio Miele ◽  
Margherita Trinci ◽  
Vito Briganti

Wandering spleen and gastric volvulus are two rare entities that have been described in association with congenital diaphragmatic hernia. The diagnosis is difficult and any delay can result in ischemia and necrosis of both organs. We present a case of a 13-year-old girl, previously operated on for anterior diaphragmatic hernia and intrathoracic gastric volvulus, that presented to our service for a subdiaphragmatic gastric volvulus recurrence associated with a wandering spleen. In this report we reviewed the literature, analyzing the clinical presentation, diagnostic assessment, and treatment options of both conditions, in particular in the case associated with diaphragmatic hernia.


2007 ◽  
Vol 11 (1) ◽  
pp. 35-39 ◽  
Author(s):  
Nishi Varshney ◽  
Anwar Al Hammadi ◽  
Hakeem Sam ◽  
A. Kevin Watters

Background: Perifolliculitis capitis abscedens et suffodiens (PCAS) is a suppurative process that involves the scalp, eventually resulting in extensive scarring and irreversible alopecia. This condition often presents in males of African American origin. Objective: This article describes the clinical presentation, diagnosis, and treatment of an Aboriginal Canadian male suffering from PCAS. A literature review on the etiology, pathology, differential diagnosis, and management is also discussed. Conclusion: Careful analysis of the pathology and clinical presentation can aid in the timely diagnosis and management of this challenging condition. The clinician dealing with patients suffering from PCAS has several treatment options available to help successfully manage patients with straightforward or recalcitrant disease.


Cells ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 327
Author(s):  
Darina Kohoutova ◽  
Dominic Worku ◽  
Hala Aziz ◽  
Julian Teare ◽  
Justin Weir ◽  
...  

Malignant melanoma (MM) has become the fifth most frequent cancer in the UK. It is the most common carcinoma to metastasize to the gastrointestinal (GI) tract. MM particularly has an affinity to spread to the small bowel, which is followed by the involvement of the stomach and large intestine. Excellent endoscopic options including video capsule endoscopy and enteroscopy are available for a precise diagnosis of GI involvement by a metastatic MM. The complete surgical resection of GI metastatic MM in carefully selected patients not only provides symptom control, but has also been associated with an increase in overall survival. The approval of BRAF-targeted therapies and immune checkpoint inhibitors has transformed therapeutic approaches for patients with metastatic MM over the past decade. Currently, the overall survival of patients with advanced metastatic MM who have been treated with a combination of immunotherapeutic agents reaches 52% at five years. The role of surgery for patients with the metastatic involvement of the GI tract with MM is evolving in the era of effective systemic treatments.


2016 ◽  
Vol 21 (3) ◽  
pp. 271-277 ◽  
Author(s):  
Jadwiga Nowak-Sadzikowska ◽  
Tomasz Walasek ◽  
Jerzy Jakubowicz ◽  
Paweł Blecharz ◽  
Marian Reinfuss

2014 ◽  
Vol 81 (1) ◽  
pp. 83-90 ◽  
Author(s):  
Nitin Agarwal ◽  
Jacqueline C. Guerra ◽  
Nihar B. Gala ◽  
Prateek Agarwal ◽  
Alexandros Zouzias ◽  
...  

Drugs ◽  
1998 ◽  
Vol 55 (6) ◽  
pp. 791-799 ◽  
Author(s):  
Graham L. Cohen ◽  
Carla I. Falkson

2015 ◽  
Vol 122 (4) ◽  
pp. 933-938 ◽  
Author(s):  
Justin A. Dye ◽  
Colin C. Buchanan ◽  
Nestor R. Gonzalez

The authors report the treatment of a rare type of dural arteriovenous fistula of the paracavernous venous plexus. These fistulas can mimic carotid-cavernous fistulas in both imaging characteristics and clinical presentation, but the anatomical differences require differences in management. The authors describe an integrated open surgical and direct endovascular embolization approach and review of the literature pertaining to the anatomy of and treatment options for paracavernous fistulas.


2018 ◽  
Vol 89 (12) ◽  
pp. 711-715 ◽  
Author(s):  
Patrycja Wreczycka-Cegielny ◽  
Tomasz Cegielny ◽  
Marcin Oplawski ◽  
Wlodzimierz Sawicki ◽  
Zbigniew Kojs

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