scholarly journals Preparation and characterization of ferromagnetic mitomycin C microcapsules as a means of magnetic control of anticancer drugs.

1979 ◽  
Vol 55 (9) ◽  
pp. 470-475 ◽  
Author(s):  
Tetsuro KATO ◽  
Ryosuke NEMOTO ◽  
Hisashi MORI ◽  
Katsuo UNNO ◽  
Akio GOTO ◽  
...  
Keyword(s):  
Mitomycin C ◽  
Anticancer Drugs ◽  
Magnetic Control

scholarly journals Synthesis, Characterization and Antiproliferative Evaluation of Pt(II) and Pd(II) Complexes with a Thiazine-Pyridine Derivative Ligand

2021 ◽  
Vol 14 (5) ◽  
pp. 395
Author(s):  
Silvia Gutiérrez-Tarriño ◽  
Javier Espino ◽  
Francisco Luna-Giles ◽  
Ana B. Rodríguez ◽  
José A. Pariente ◽  
...  
Keyword(s):  
Cell Lines ◽  
Anticancer Drugs ◽  
Platinum Complexes ◽  
Chemotherapeutic Agents ◽  
Pyridine Derivative ◽  
Cervix Carcinoma ◽  
Multinuclear Complexes ◽  
Histiocytic Lymphoma ◽  
Ovary Adenocarcinoma

Chemical, pharmacological, and clinical research on anticancer coordination complexes has led to noteworthy anticancer drugs such as cisplatin, carboplatin and oxaliplatin. Although these compounds are effective chemotherapeutic agents in the treatment of different tumors, they are associated with high toxicity and numerous side effects. Several studies have shown that the range of platinum complexes with antitumor activity is not limited to structural analogs of cisplatin. Therefore, the development of convenient anticancer drugs that can be effectively used for the treatment of human tumors has become the main goal of most research groups in this field. In this sense, active platinum complexes without NH groups, transplatinum complexes, multinuclear complexes, cationic complexes, and several classes of palladium(II) complexes have emerged. Herein, the synthesis and characterization of two Pt(II) or Pd(II) complexes with PyTz (2-(2-pyridyl)iminotetrahydro-1,3-thiazine), a thiazine derivative ligand, with the formula [MCl2(PyTz)]·C2H6O (M = Pt(II) or Pd(II)) were reported. The potential anticancer ability of both complexes was evaluated in epithelial cervix carcinoma HeLa, human ovary adenocarcinoma SK-OV-3, human histiocytic lymphoma U-937, and human promyelocytic leukemia HL-60 cell lines. Interestingly, the Pt(II) complex showed great cytotoxic potential against all tumor cell lines tested, whereas the Pd(II) complex displayed slight antitumor actions.

scholarly journals cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339

2017 ◽  
Vol 46 (35) ◽  
pp. 11925-11941 ◽  
Author(s):  
Gabriel E. Büchel ◽  
Susanne Kossatz ◽  
Ahmad Sadique ◽  
Peter Rapta ◽  
Michal Zalibera ◽  
...  
Keyword(s):  
Anticancer Drugs ◽  
Synthesis And Characterization ◽  
Cis Isomer ◽  
The Way

The synthesis and characterization of cis-[OsIVCl4(κN2-1H-indazole)2] and its 1e-reduced analog are reported.

Characterization of mitomycin C-induced gastrointestinal damage: changes in the gastric absorption of drugs in rats

1986 ◽  
Vol 38 (9) ◽  
pp. 663-667 ◽  
Author(s):  
Masayuki Mizuno ◽  
Shigeki Kawabata ◽  
Mitsuru Hashida ◽  
Hitoshi Sezaki
Keyword(s):  
Mitomycin C ◽  
Gastrointestinal Damage

Isolation and characterization of mitomycin-C-sensitive mouse lymphoma cell mutants

1983 ◽  
Vol 108 (1-3) ◽  
pp. 405-416 ◽  
Author(s):  
Hiroko Hama-Inaba ◽  
Naoko Hieda-Shiomi ◽  
Tadahiro Shiomi ◽  
Koki Sato
Keyword(s):  
Mitomycin C ◽  
Lymphoma Cell ◽  
Isolation And Characterization ◽  
Mouse Lymphoma

Characterization of mitomycin C-induced gastrointestinal damage

1989 ◽  
Vol 97 (3) ◽  
pp. 415-423 ◽  
Author(s):  
Masayuki Mizuno ◽  
Shigeki Kawabata ◽  
Takeshi Hamaura ◽  
Mitsuru Hashida ◽  
Hitoshi Sezaki
Keyword(s):  
Mitomycin C ◽  
Gastrointestinal Damage

Characterization of Liposomes and an Emulsion Containing Mitomycin C or Lipophilic Mitomycin C Prodrugs

1986 ◽  
Vol 75 (12) ◽  
pp. 1166-1170 ◽  
Author(s):  
Hitoshi Sasaki ◽  
Toshiyuki Kakutani ◽  
Mitsuru Hashida ◽  
Hitoshi Sezaki
Keyword(s):  
Mitomycin C

Preparation and characterization of Mitomycin-C loaded chitosan-coated alginate microspheres for chemoembolization

2005 ◽  
Vol 22 (2) ◽  
pp. 167-178 ◽  
Author(s):  
Y. Misirli ◽  
E. Öztürk ◽  
H. Kurşaklioğlu ◽  
E. B. Denkbaş
Keyword(s):  
Mitomycin C
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