scholarly journals State of Nonspecific Host Defense in Patients with Pyoinflammatory Diseases of Soft Tissues and Its Correction by Photomodification

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
N. Zheliba ◽  
S. Khimich ◽  
R. Chornopyshchuk ◽  
I. Oshovskyy ◽  
P. Shevnya

The results of research of performance factors of nonspecific defense of 116 patients with acute purulent inflammation of soft tissues were analyzed. The regularities of these parameters inhibition were detected depending on the severity of the inflammatory process. The use of the ultraviolet and laser radiation equally stimulates increase in the levels of factors of nonspecific host defense and promotes positive course of the disease.

2012 ◽  
Author(s):  
Mariusz Kastek ◽  
Tadeusz Piatkowski ◽  
Henryk Polakowski ◽  
Andrzej Zajac

1994 ◽  
Author(s):  
Victor N. Balin ◽  
Alexey S. Gook ◽  
Vladimir N. Koshelev ◽  
Sergey P. Kropotov ◽  
Tatyana A. Kusovkova ◽  
...  

2013 ◽  
Vol 20 (2) ◽  
pp. 12-19
Author(s):  
R. M Tikhilov ◽  
D. I Kutyanov ◽  
L. A Rodomanova ◽  
A. Yu Kochish

Potentialities of reconstructive and plastic microsurgery in patients with different pathology of large joints of the extremities were studied. Results of 265 microsurgical operations with pedicle flap (65.7%) and free tissue (34.3%) grafting were assessed. It was shown that use of microsurgical techniques provided reconstruction of full value para-articular soft tissues, increased range of joint movement and created the conditions for effective arrest of local inflammatory process. Besides, they possessed potentialities for the performance and increase of the efficacy in arthroplasty and some other high technology operations on large joints. The more distally the joint is located the higher is the need in reconstructive-plastic microsurgical operations and free tissue grafting on upper and lower extremities.


2021 ◽  
pp. 5-13
Author(s):  
E.M. Danko ◽  
Ye.Ya. Kostenko ◽  
S.B. Kostenko ◽  
V.V. Pantyo

Topic relevance. Periodontal tissue diseases currently take a significant place among infectious diseases, both in dentistry and in medicine in general. Traditional methods of treatment of inflammatorydystrophic periodontal diseases do not bring the desired results, so the question arises of finding alternative, non-drug treatments. Among such means, special attention is paid to the use of various types of low-intensity radiation, as well as the cumulative effect of light and photosensitizers. The aim of the study is to analyze literary sources regarding the use of various types of low-intensity radiation in the treatment of periodontal tissue diseases. Materials and methods. The research and analysis of scientific literature on the basis of Google Scholar, Research Gate, Wiley Online Library and Academia.edu on the use of various types of radiation in the treatment of periodontal tissue diseases was carried out. Results and discussion. Laser radiation shows anti-inflammatory, antimicrobial, immunomodulatory and desensitizing effect, stimulates tissue reparation, and also reduces histohemmatic barriers in the inflammatory process, reduces gum hyperemia, which indicates the high efficiency of this method in optimizing the processes of restoring periodontal structures. With wavelengths of 630 and 870 nm, laser radiation at certain parameters increases the sensitivity of S. aureus and P.aeruginosa to commonly used antibiotics. With long-term exposure, PILER (polychromatic polarized incoherent low-energy radiation) has a similar effect on soft tissues, which improves the results of treatment of chronic catarrhal gingivitis in complex therapy, activates regenerative processes, reduces the spread and pain, normalizes immune processes. Polychromatic and monochromatic PILER shows a pronounced antimicrobial effect against opportunistic pathogens, although complete data on its use in periodontology is not yet available. LED radiation, in turn, also increases the sensitivity of conditionally pathogenic microorganisms to some antibiotics, causes improvement of oral hygiene indicators, bleeding of gums and stabilization of tooth mobility, inhibits the activation of pro-inflammatory cytokins, has a biostimulating effect on gum fibroblast and antiinflammatory effect. Experimental studies show that the use of low-intensity radiation and photosensitizers for photodynamic treatment (PDT) show significant improvement of treatment outcomes in periodontal patients. Thus, PDT in combination with mechanical cleaning of periodontal pockets leads to a significant decrease in their depth compared to traditional treatment methods. Conclusion. Application of various methods of irradiation of periodontal tissues using a certain dose of low-intensity radiation, wavelength and exposure, both individually and in combination with photosensitizers, can be employed in the treatment of inflammatory and inflammatory-dystrophic periodontal diseases as an effective antimicrobial method.


2013 ◽  
Vol 17 (3 (67) p.1) ◽  
pp. 159-160
Author(s):  
V. K. Sokol

A search and improvement of the methods of a medicolegal examination in relation to the prescription of the origin of injuries of the soft tissues, in particular, the skin and muscles, stipulate a necessity of studing of new aspects in the dynamics of an inflammatory process for a substantiation and elaboration of the necessary criteria which will allow to solve questions about the prescription of injuries.


2021 ◽  
Vol 5 (5) ◽  
pp. 330-334
Author(s):  
N.A. Sholokhova ◽  
◽  
E.B. Olkhova ◽  
◽  
◽  
...  

Aim: to study the possibilities of diagnostic radiology methods for changes in metaphyses and epiphyses at an early stage of the inflammatory process in children aged 1 and older and adolescents. Patients and Methods: 76 emergency patients with a diagnosis of acute metaepiphysial hematogenous osteomyelitis were examined using standard radiography (SR), ultrasonography (US), magnetic resonance imaging (MRI) and computed tomography (CT). The age of the patients ranged from 1 to 18 years. All patients in the admission department underwent US and SR with a mandatory examination of the contralateral region. After analyzing the obtained data, additional examination algorithms were formed using MRI and CT. Results and Discussion: US of the targeted area was descriptive concerning the soft tissue pathological component: paraosseous soft tissues edema was determined in 75%, structural changes of the joint, in particular, synovitis — in 78.9%, joint effusion — in 57.9%. X-ray examination had a limited opportunity to detect destructive changes in bone tissue at the early stages of the pathological process (6.6%). At the same time, MRI revealed the maximum number of semiotic signs of acute hematogenous osteomyelitis, the most significant of which were: trabecular bone marrow edema (100%), periosteal changes (96.1%) and extraosseous changes (98.5%). CT was performed in 26 patients with multifocal disease, as well as in the late stage of the inflammatory process for preoperative planning. Bone destruction at an early stage occurred in 32.7% of patients, a change in the growth area — in 81.0 % of cases. Along with these semiotic signs, sequesters (55.3 %) and fistula tracts (31.3%) were visualized. Conclusion: the obtained results made it possible to systematize information on the diagnostic radiology efficacy for acute metaphyseal and epiphyseal lesions in the early stage of the inflammatory process in children aged 1 and older and adolescents. KEYWORDS: osteomyelitis, epiphysis, metaphysis, diagnostic radiology, pediatrics. FOR CITATION: Sholokhova N.A., Olkhova E.B. On the issue of complex diagnostic radiology of inflammatory bone diseases in children at an early stage. Russian Medical Inquiry. 2021;5(5):330–334 (in Russ.). DOI: 10.32364/2587-6821-2021-5-5-330-334.


2021 ◽  
Vol 26 (2) ◽  
pp. 26-32
Author(s):  
A.Ye. Demkovych ◽  
Yu.I. Bondarenko ◽  
O.O. Fastovets ◽  
A.O. Hrad ◽  
P.A. Hasiuk ◽  
...  

The article presents an assessment of the dynamics of changes in the content of the marker of collagenolysis – free oxyproline in the homogeniate of soft tissues and bone in experimental bacterial-immune periodontitis and elucidation of the effect of flavonol quercetin on these indicators. The aim of this study was to determine the role of cytokinogenesis and the effect of flavonol on it in the pathogenesis, development and course of experimental periodontitis. During the experiment, a fragment of the mandible was taken from the animals, from which the soft tissues and bone were carefully separated. The state of collagen was determined by the content of free oxyproline in the soft and bone tissues. The concentration was determined according to the calibration graph and expressed in μmol/g. The results of studies of the indicators of the state of biopolymers of connective tissue structures of periodontium on the 7th, 14th and 30th day of experimental bacterial-immune periodontitis and after its correction with flavonol (from the 7th to the 14th day of the experiment) are presented. The data on the nature of changes in the content of collagen monomers in the process of formation of the inflammatory focus in the periodontal complex are given. During the acute phase of the inflammatory process in rats there was revealed a slight increase in blood free oxyproline in bone homogenate and homogenate of soft periodontal tissues, on the 14th day the dynamics continued to increase, at a later stage of the experiment, namely on the 30th day, increase in bone resorption continued  as compared to the 7th and 14th day. During the correction of disorders resulted from  the development of this pathological process there was a decrease in the level of free oxyproline in the bone homogenate and homogenate of soft tissues of mandibular periodontium, as compared to the same indicators of animals who did not receive quercetin on the 14th day. The use of flavonol quercetin, which, by affecting immune processes, limited the inflammatory response in periodontal tissues and stabilized collagenolysis processes in periodontal tissues was manifested by a decrease in free oxyproline in bone and soft tissue homogenates of experimental animals.


2020 ◽  
Vol 16 (2) ◽  
pp. 64-72
Author(s):  
Yevgenia Durnovo ◽  
Artem Fedorichev ◽  
Andrey Klochkov ◽  
Ekaterina Galkina ◽  
Irina Shalenkova

Subject. The article presents the results of a comprehensive method for the treatment of acute perforated maxillary sinusitis using the developed surgical method for eliminating perforation with a subepithelial vascular palatal flap with simultaneous use of PRF. The effectiveness of the proposed method of treatment was confirmed by x-ray data characterizing the intensity of the inflammatory reaction caused by surgery, morphological parameters of soft tissues in the alveolar process of the upper jaw in the area of intervention and the state of the maxillary sinus before and 3 months after surgery. The aim of the study was to evaluate the effectiveness of the use of subepithelial vascular palatal flap and PRF in the complex treatment of acute odontogenic perforated maxillary sinusitis. Methodology. An assessment and comparative analysis of the activity of the inflammatory process caused by surgery, as well as the study and comparison of the morphological parameters of the alveolar ridge (the depth of the vestibule of the oral cavity, the width of the keratinized gums, and the thickness of the mucous membrane), the X-ray data evaluating the state of the maxillary sinus, before and after 3 months were carried out. after surgical procedures. The study involved 50 patients with acute perforated maxillary sinusitis (J01.0), who were divided into two groups: the main and comparisons. In the main group (25 people), a new developed method of surgical treatment was used (a method of subepithelial vascularized palatal flap with simultaneous use of PRF), in the comparison group (25 people), the traditional method of complex treatment, including a mobilized mucoperiosteal cheek flap to eliminate perforation of the maxillary sinus . Results. Based on the analysis of the data, pronounced manifestations of the inflammatory process of the postoperative period and negative treatment results using the traditional technique, which were absent in the treatment of patients with the developed surgical method, were revealed. Findings. An analysis of the results obtained during the study revealed the high efficiency of the developed method in comparison with the traditional one.


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