scholarly journals Incidence of Progression into Ménière Disease from Idiopathic Sudden Sensorineural Hearing Loss: Midterm Follow-up Study

2018 ◽  
Vol 17 (3) ◽  
pp. 95-101
Author(s):  
Byeong Min Lee ◽  
Jin Hyun Seo ◽  
Hyun Woo Park ◽  
Hyun Jin Lee ◽  
Dong Gu Hur ◽  
...  
2019 ◽  
Vol 46 (3) ◽  
pp. 353-359 ◽  
Author(s):  
So Young Kim ◽  
Mi Kyung Kim ◽  
Jae-Sung Lim ◽  
Il Gyu Kong ◽  
Hyo Geun Choi

2019 ◽  
Vol 16 (4) ◽  
pp. 324-327 ◽  
Author(s):  
Hsin-Chien Chen ◽  
Chi-Hsiang Chung ◽  
Chieh-Hua Lu ◽  
Wu-Chien Chien

Background: The risk of sudden sensorineural hearing loss associated with metformin use in patients with diabetes mellitus has not been fully examined. Study design: It is a retrospective matched-cohort study. Subjects and methods: We examined the medical records of patients with diabetes mellitus over 18 years old in Taiwan’s National Health Insurance Research Database for the period between 1 January 2000 and 31 December 2013, to establish matched cohorts (14,109 with and 42,327 without metformin use) at a ratio of 1:3 by sex, age and index year. Results: We used a Cox regression hazard model to identify risk factors of sudden sensorineural hearing loss during 14 years of follow-up, and the results indicate that a significantly lower percentage of diabetes mellitus patients with metformin use ( p = 0.033) developed sudden sensorineural hearing loss compared with those without metformin use (0.21%, 29/14,109 vs 0.32%, 136/42,327). After adjustment for age and other variables [adjusted hazard ratio: 0.630 (95% confidence interval: 0.422–0.941, p = 0.024)], this study also demonstrated that metformin use appeared to reduce the risk of developing sudden sensorineural hearing loss. Conclusion: This study demonstrated an association between metformin use and lower incidence of sudden sensorineural hearing loss among patients with diabetes mellitus.


1994 ◽  
Vol 37 (4) ◽  
pp. 310-315
Author(s):  
Eiji Chida ◽  
Nobukiyo Satoh ◽  
Mitsugu Kawanami ◽  
Masaaki Kashiwamura ◽  
Satoshi Fukuda ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document