scholarly journals Alergeny ziół kulinarnych i warzyw ważne dla pielęgniarki lub dietetyczki

2020 ◽  
Vol 5 (3) ◽  
pp. 117-136
Author(s):  
Krzysztof Buczyłko ◽  
Keyword(s):  
At Risk ◽  
Allergic Diseases ◽  
Cross Reactivity ◽  
Oral Allergy Syndrome ◽  
Molecular Allergology ◽  
Culinary Herbs

Introduction. New allergenic sources causing the oral allergy syndrome and other allergic diseases have been reported. Overview. The spices, vegetables and some culinary herbs allergenic mole-cules have been identified and presented with their cross-reactivity possibili-ties. Some of the molecules generally considered not to be at risk for severe reactions have been demonstrated to pose a threat for inducing generalized reactions. Conclusions. Molecular allergology basic rules are useful for nurses and dieti-tians as well.

scholarly journals Sublingual Reactivity to rBET V1 and rPHL P1 in Patients with Oral Allergy Syndrome

2006 ◽  
Vol 19 (1) ◽  
pp. 205873920601900 ◽  
Author(s):  
F. Marcucci ◽  
L. Sensi ◽  
G. DI Cara ◽  
G. Gidaro ◽  
C. Incorvaia ◽  
...  
Keyword(s):  
Specific Ige ◽  
Cross Reactivity ◽  
Oral Allergy Syndrome ◽  
Control Group ◽  
Recombinant Allergens ◽  
Natural Extracts ◽  
Target Organs ◽  
High Concentrations

Oral Allergy Syndrome (OAS) in patients with pollen-induced rhinoconjunctivitis is caused by specific IgE recognizing cross-reacting epitopes of fruits and plants, which were clearly shown in vitro, but failed to be demonstrated in vivo by cross-challenges in the target organs. Considering the hypothesis of degradation of such epitopes in natural extracts, challenges with recombinant pollen allergens were done to evaluate the reactivity of the oral mucosa in OAS patients. Seventeen patients with OAS and rhinitis from birch (10) and grass pollen (7) and 10 non-atopic controls were studied by skin prick tests (SPT), allergen specific nasal challenges (ASNC) and allergen specific sublingual challenges (ASSC) with birch and timothy extracts and with rBet v1 and rPhl p1 at increasing concentrations from 1 to 1000 mcg/ml. None of the healthy subjects in the control group had any positive test for birch and timothy extracts or for recombinant allergens. In the OAS group the following results were observed: SPTs with recombinant allergens were positive in all patients, mostly at 10 mcg/ml concentration; ASNC with rBet v1 were positive in all patients, mostly at 100 mcg/ml; ASSC with natural pollen extracts were positive in only 2 of 17 patients, but in 15 of 17 with rBet v1 and rPhl p1, mostly at 500 mcg/ml and 1000 mcg/ml. ASSC with rBet v1 and rPhl p1 were positive with a mean concentration of 677 and 533 mcg/ml, respectively. The results of sublingual challenges with rBet v1 and rPhl p1 showed the in vivo cross-reactivity between pollens and foods in patients with OAS, but high concentrations of the recombinant allergens were needed to reproduce oral symptoms, thus explaining the failure of challenges performed with natural extracts, which have concentrations of major allergens lower than 50 mcg/ml. This indicates that sublingual mucosa is much less reactive to allergens than other surfaces, such as skin and nasal mucosa, probably because of its anatomic and immunologic peculiarity.

scholarly journals Allergic diseases of the skin and drug allergies – 2012. Is there association between duration of seasonal alleric rhinitis and oral allergy syndrome?

2013 ◽  
Vol 6 ◽  
pp. P99
Author(s):  
Reza Faridhosseini ◽  
Farahzad Jabbari ◽  
Afshin Shirkani ◽  
Mohammad Reza Zandkarimi ◽  
Hadis Yousefzadeh
Keyword(s):  
Allergic Diseases ◽  
Oral Allergy Syndrome

scholarly journals Molecular allergology approach to allergic diseases in the paediatric age

2009 ◽  
Vol 35 (1) ◽  
pp. 29 ◽  
Author(s):  
Claudia Alessandri ◽  
Danila Zennaro ◽  
Alessandra Zaffiro ◽  
Adriano Mari
Keyword(s):  
Allergic Diseases ◽  
Molecular Allergology ◽  
Paediatric Age

Evaluation of food-pollen cross-reactivity by nose-mouth cross-challenge in pollinosis with oral allergy syndrome

Allergy ◽  
2005 ◽  
Vol 60 (4) ◽  
pp. 501-505 ◽  
Author(s):  
F. Marcucci ◽  
F. Frati ◽  
L. Sensi ◽  
G. D. Cara ◽  
E. Novembre ◽  
...  
Keyword(s):  
Cross Reactivity ◽  
Oral Allergy Syndrome

Food-pollen cross-reactivity in oral allergy syndrome and rhinitis

2003 ◽  
Vol 111 (2) ◽  
pp. S103
Author(s):  
F. Marcucci ◽  
G.W. Canonica ◽  
F. Frati ◽  
L. Sensi ◽  
A. Riccio ◽  
...  
Keyword(s):  
Cross Reactivity ◽  
Oral Allergy Syndrome

Lipid Transfer Protein Sensitization: Risk of Anaphylaxis and Molecular Sensitization Profile in Pru p 3-Sensitized Patients

2020 ◽  
pp. 1-8
Author(s):  
Maria Ruano-Zaragoza ◽  
Maria Luisa Somoza ◽  
Teodorikez Wilfox Jiménez-Rodriguez ◽  
Victor Soriano-Gomis ◽  
Purificación González-Delgado ◽  
...  
Keyword(s):  
Lipid Transfer Protein ◽  
Allergic Diseases ◽  
Specific Ige ◽  
Oral Allergy Syndrome ◽  
Skin Tests ◽  
Food Allergies ◽  
Lipid Transfer ◽  
Cross Sectional ◽  
Positive Skin ◽  
Pru P 3

<b><i>Background:</i></b> Component-resolved diagnosis reveals the IgE response to many inhaled, food, and other allergens, improving the understanding and diagnosis of allergic diseases. <b><i>Objective:</i></b> The aims of the study are to study the recognition of different lipid transfer proteins (LTPs) and other allergen families in a large group of people sensitized to Pru p 3 and to analyze the relationship between the clinical entities and the allergens. <b><i>Methods:</i></b> This cross-sectional study included a large cohort of patients with positive skin tests to peach fruit and Pru p 3 specific IgE antibodies. Respiratory and food allergy symptoms were collected, and we performed prick tests with pollen, plant food, and other allergens plus the ImmunoCAP ISAC assay. <b><i>Results:</i></b> Our sample consisted of 421 people with a mean age of 33.25 years (range 16–68); 54.6% were women. Clinical entities included anaphylaxis (37.1%), urticaria (67.9%), and oral allergy syndrome (59.1%). Rhinitis, rhinoconjunctivitis, and/or asthma were diagnosed in 71.8% of the participants. The most pronounced correlation existed between sensitization to Pru p 3 and to Jug r 3, Pla a 3, Ara h 9, and Cor a 8. We found a higher incidence of anaphylaxis in people with 5 or more recognized LTPs. No association was observed between inhaled and food allergies. <b><i>Conclusion:</i></b> Most Pru p 3-sensitized participants were sensitized to additional allergens from the same family and, to a lesser extent, to other allergens, mainly in the profilin and PR-10 protein families. Anaphylaxis occurred in more than a third of the cases evaluated, and almost three-quarters of them had respiratory symptoms. Respiratory and food allergies involving LTPs do not seem to be associated.

scholarly journals Identification of B Cell Epitopes of Blo t 13 Allergen and Cross-Reactivity with Human Adipocytes and Heart Fatty Acid Binding Proteins

2019 ◽  
Vol 20 (24) ◽  
pp. 6107 ◽  
Author(s):  
Marlon Múnera ◽  
Dalgys Martínez ◽  
Alexis Labrada ◽  
Luis Caraballo ◽  
Leonardo Puerta
Keyword(s):  
Fatty Acid ◽  
B Cell ◽  
Immunoglobulin E ◽  
Allergic Diseases ◽  
Cross Reactivity ◽  
Fatty Acid Binding Proteins ◽  
Serum Samples ◽  
Fatty Acid Binding ◽  
B Cell Epitopes ◽  
Human Sera

Cross-reactivity between allergens and human proteins could have a clinical impact in allergic diseases. Blo t 13 is an allergen from the mite Blomia tropicalis, which belongs to the fatty acid binding protein (FABP) family and has structural homology with human FABPs. This work aimed to map B cell epitopes on Blo t 13 and to identify epitopes involved in cross-reactivity with human heart FABP (FABP3) and adipocyte FABP (FABP4). Sera from 25 patients with house dust mite (HDM) allergy that were sensitized to Blo t 13 were used for testing the reactivity of immunoglobulin E (IgE) and IgG to FABP. The epitope mapping of Blo t 13 was performed using overlapping peptides, and cross-reactivity between Blo t 13 and human FABP was analyzed using human sera and anti-Blo t 13 monoclonal antibodies. IgE antibodies to all FABPs were detected in 14/25 serum samples, and IgG was detected in 25/25 serum samples. The cross-reactivity of Blo t 13 was 42% with FABP3 and 48% with FABP4. Two IgE-binding regions were identified in Blo t 13; one between residues 54 and 72 (the main cross-reacting region) and another between residues 111 to 129. Our results suggest that exposure to the Blo t 13 allergen could induce an auto-reactive response to endogenous FABP in allergic patients sensitized to Blo t 13.

scholarly journals Oral allergy syndrome in children with pollen sensitization in Tomsk region

2016 ◽  
Vol 13 (6) ◽  
pp. 58-62
Author(s):  
M M Fedotova ◽  
O S Fedorova ◽  
L M Ogorodova ◽  
T A Evdokimova
Keyword(s):  
Skin Prick Testing ◽  
Clinical Stage ◽  
Specific Ige ◽  
Cross Sectional Study ◽  
Cross Reactivity ◽  
Oral Allergy Syndrome ◽  
Pollen Allergens ◽  
Cross Sectional ◽  
Bet V 1 ◽  
Tomsk Region

Background. Oral allergy syndrome (OAS) is defined as immediate IgE-mediated allergic reaction localized in the oral mucosa and developing after consuming raw fruits, vegetables, nuts, legumes in pollen sensitized patients. Objective. To study the prevalence of OAS in children in the Tomsk region. Material. The cross-sectional study in random groups of primary schoolchildren aged 7-10 years (n=13 010) from the Tomsk region, Russia, was performed in frames of (EuroPrevall, № FP6-2006-TTC-TU-5 Proposal 045879). During the screening phase a survey with standardized questionnaire was carried out. Clinical stage (n=1288) included clinical interviewing with parents/guardians, the clinical examination of patients, skin prick testing with extracts of food and pollen allergens (ALK-Abello, Spain), measurement of specific IgE level in serum to food and pollen allergens, component resolved diagnostics (ImmunoCAP, Phadia, Sweden). Results. OAS registered in 13,71% of children with pollen sensitization. The main triggers were apples, carrots, peaches, peanuts. Main cause of OAS in the Tomsk region was cross-reactivity to Bet v 1 - homologues belonging to PR-10 family: to apple - Mal d 1 (r=0,92; p=0,01); to peach - Pru p1 (r=0,87; p=0,01); to peanut - Ara h 8 (r=0,74; p=0,01); to hazelnut - Cor a 1 (r=0,76; p=0,01); to carrot - Dau c 1 (r=0,54; p=0,01). Conclusion. OAS was observed in 13,71% of children with pollen sensitization and was developesed due to crossreactivity to the birch allergen Bet v 1.

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