scholarly journals Successful haemofiltration therapy in severe phenobarbital overdose

2018 ◽  
Vol 11 (2) ◽  
Author(s):  
Elizabeth Wei Tan ◽  
Maximilian Moser ◽  
Graeme Duke
2013 ◽  
Vol 2013 (nov21 1) ◽  
pp. bcr2013010011-bcr2013010011 ◽  
Author(s):  
K. Hoyland ◽  
M. Hoy ◽  
R. Austin ◽  
M. Wildman

1982 ◽  
Vol 16 (7-8) ◽  
pp. 613-614 ◽  
Author(s):  
Todd J. Brown ◽  
Larry A. Bauer ◽  
H. Richard Miyoshi

A case that utilizes a pharmacokinetic approach to evaluate the need for withdrawal prophylaxis after a phenobarbital overdose is presented. To date, the practitioner has had to rely on an accurate drug-use history to predict which patients may be at risk for withdrawal symptoms. Since this information is often difficult to obtain, some other means of identifying potential withdrawal-syndrome patients would be useful. This case describes the successful use of kinetically determined parameters, the elimination rate constant and half-life, in predicting withdrawal potential. This easily used kinetic approach may provide practitioners with a useful tool for predicting those patients at risk for withdrawal symptoms following phenobarbital overdose.


JAMA ◽  
1982 ◽  
Vol 247 (17) ◽  
pp. 2400-2401 ◽  
Author(s):  
M. J. Goldberg

2016 ◽  
Vol 45 (5) ◽  
pp. 223
Author(s):  
V Lily Limantara ◽  
Made Widia ◽  
Ketut Suwitra ◽  
Endah Ardjana

This report describes a patient with life-threat-ening phenobarbital overdose, treated successfullywith hemodialysis, using a high-flux, high-efficiencydialyzer and high blood flow rates. The rapid fall inphenobarbital levels and the dramatic clinical re-sponse noted during the procedure supports thistechnique as an effective therapy in such patients.


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