scholarly journals An open label single arm prospective clinical study in the management of Pakshaghata (CVA due to infarct) with Maharasnadi Kashaya and Shunti Churna

2020 ◽  
Vol 5 (05) ◽  
pp. 59-64
Author(s):  
Rohan Mohandas ◽  
Muttappa Totad ◽  
Vasantha B ◽  
Sphoorthi Narasimhan
Keyword(s):  
Clinical Study ◽  
Outcome Measures ◽  
Sampling Method ◽  
Primary Outcome ◽  
Tertiary Hospital ◽  
P Value ◽  
Prospective Clinical Study ◽  
Open Label ◽  
Scale Parameters ◽  
Maximum Improvement

Pakshaghata is one among 80 Vata Namathmaja Vyadhi. In Pakshaghata vitiated Vata resides in one half of body and causes Vishoshana of Sira and Snayu leading to loosening of joints results into manifestation of symptoms like Cheshta Nivrutti, Ruja and Vakstambha. Pakshaghata can be correlated to stroke or CVA. The study aims to evaluate the combined effectiveness of Maharasnadi Kashaya with Shunti Churna as Anupana in management of Pakshaghata (CVA due to infarct). The open label prospective clinical study was conducted among the 32 patients of Pakshaghata by convenient sampling method at a tertiary Hospital Sri Dharmasthala Manjunatheshwara College of Ayurveda and Hospital, Hassan, Karnataka from December 2018 to December 2019. The effectiveness of the drug showed improvement in primary outcome measures such as Cheshta Nivrutti, Vakstambha and Ruk in subjects of Pakshaghata with p value less than 0.05. In this study, maximum improvement was found in “Ruk” followed by “Cheshta Nivrutti” and then “Vak Stambha”. Hence this drug is more effective in “Saruja Pakshaghata” hence; it showed improvement in the NIH stroke scale parameters with p value less than 0.05. The combined effectiveness of Maharasnadi Kashaya with Shunti Churna as Anupana in management of Pakshaghata (CVA due to Infarct) is proved.

scholarly journals An open label single arm prospective clinical study on Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana in Pakshaghata (CVA due to Infarct)

2019 ◽  
Vol 4 (06) ◽  
Author(s):  
Yadu Gopan ◽  
Totad Muttappa ◽  
Vasantha B. ◽  
Kiran K.
Keyword(s):  
Clinical Study ◽  
Outcome Measures ◽  
Ordinal Data ◽  
Secondary Outcome ◽  
Prospective Clinical Study ◽  
Rank Tests ◽  
Open Label ◽  
Signed Rank ◽  
Non Parametric

Background: Pakshaghata is one among the 80 vataja nanatmaja vikara and is a roga of madhyama roga marga. Vatavyadhi is considered to be one among the ashta mahagadas. Vatagajankusha rasa is a combination of vyosha, bhasmas, vatsanabha, karkatasringi, haritaki etc. It has vatakaphahara, vikasi, vyavayi, rasayana etc properties. It is said to be effective in treating pakshaghata in 7 days if given along with Pippali churna and Manjishta kwatha. Aims and Objectives: To evaluate the efficacy of Vatagajankusha rasa with Pippali churna and Manjishta kwatha as anupana in the management of pakshaghata (CVA due to infarct). Methodology: Among 32 registered patients, 30 completed the course of treatment. They were administered with Vatagajankusha rasa 1 tablet (125 mg) after food with anupana 3gm Pippali churna and 15 ml Manjishta kwatha twice daily (morning and evening) for a period of 7 days. Nominal and ordinal data were analysed using non parametric tests like McNemar and Wilcoxon’s signed rank tests respectively. Result: There was statistically significant improvement in the primary and secondary outcome measures (p less than 0.05 was observed). Conclusion: Vatagajankusha rasa with Pippali churna and Manjishta kwatha as anupana is effective in the management of Pakshaghata (CVA due to infarct).

scholarly journals An open label single arm prospective clinical study on Vatagajankusharasa with Pippali Churna and Manjishta Kwatha as Anupana in Viswachi (cervical spondylosis)

2020 ◽  
Vol 5 (01) ◽  
pp. 73-80
Author(s):  
Moh Gulfam ◽  
Totad Muttappa ◽  
Neelam Bisht ◽  
Vishnu M L ◽  
Yadu Gopan
Keyword(s):  
Clinical Study ◽  
Ordinal Data ◽  
Cervical Spondylosis ◽  
Signs And Symptoms ◽  
Upper Extremities ◽  
Secondary Outcome ◽  
Prospective Clinical Study ◽  
Rank Tests ◽  
Open Label ◽  
Signed Rank

Background: Viswachi is one among the 80 Nanatmaja Vata Vyadhi. This disease affects the neck and upper extremities with the signs and symptoms like Ruk, Stambha, Toda, Bahu Karmakshaya. Vatagajankusha Rasa is a combination of Vyosha, Bhasmas, Vatsanabha, Karkatasringi, Haritaki etc. It has Vatakaphahara, Vikasi, Vyavayi, Rasayana etc. properties. It is said to be effective in treating Visawachi in 7 days if given along with Pippali Churna and Manjishta Kwatha. Aims and Objectives: To evaluate the efficacy of Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana in the management of Viswachi (Cervical spondylosis). Methodology: Among 35 registered patients, 30 completed the course of treatment. They were administered with Vatagajankusha Rasa 1 tablet (125 mg) after food with Anupana 3gm Pippali Churna and 15 ml Manjishta Kwatha twice daily (morning and evening) for a period of 7 days. Nominal and ordinal data were analysed using non parametric tests like McNemar and Wilcoxon’s signed rank tests respectively. Result: Assessment parameters like Ruk, Toda, Sthambha and Bahukarma Kshya. There was statistically significant improvement in the primary and secondary outcome measures (p less than 0.05 was observed). Conclusion: Vatagajankusha Rasa with Pippali Churna and Manjishta Kwatha as Anupana is effective in the management of Viswachi (Cervical spondylosis).

scholarly journals Douching With Water Works Device for Perceived Vaginal Odor With or Without Complaints of Discharge in Women With No Infectious Cause of Vaginitis: A Pilot Study

2006 ◽  
Vol 2006 ◽  
pp. 1-4 ◽  
Author(s):  
Ashwin J. Chatwani ◽  
Sarmina Hassan ◽  
Salma Rahimi ◽  
Stacey Jeronis ◽  
Vani Dandolu
Keyword(s):  
Pilot Study ◽  
Outcome Measures ◽  
Primary Outcome ◽  
Secondary Outcome ◽  
Open Label ◽  
Significant Change

Objective. To determine if douching with Water Works device for 1 month can (1) lower or eliminate perceived vaginal odor by subject; (2) have any effects on vaginal ecosystem.Methods. Ten women with perceived vaginal odor with or without discharge, douched every day for 4 weeks in an open-label, nonrandomized pilot study. Primary outcome measures included perceived vaginal odor by subject, lactobacilli score from Nugent slide, and acceptance of the Water Works douching system. Secondary outcome included the safety of using this douching device.Results. At week 4, there was improvement in vaginal odor (P=.0006) and there was no significant change in lactobacilli score.Conclusion. Douching with Water Works device is associated with reduction or elimination of vaginal odor without adversely affecting the vaginal ecosystem.

scholarly journals Redefining face contour with a novel anti-aging cosmetic product: an open-label, prospective clinical study

2017 ◽  
Vol Volume 10 ◽  
pp. 473-482 ◽  
Author(s):  
Aurora Garre ◽  
Gemma Martinez-Masana ◽  
Jaime Piquero-Casals ◽  
Corinne Granger
Keyword(s):  
Clinical Study ◽  
Prospective Clinical Study ◽  
Open Label ◽  
Cosmetic Product ◽  
Face Contour
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