scholarly journals A randomized clinical study to evaluate the effect of Saptachakra in management of Madhumeha w.s.r. to type 2 diabetes mellitus

2020 ◽  
Vol 5 (02) ◽  
pp. 30-38
Author(s):  
Gargee RB ◽  
Gopalakrishna G ◽  
Sowmyashree UP

Background: Non-communicable diseases are posing major health and development threats. The Worldwide, approximately 200 million people currently have type 2 DM, a prevalence that has been predicted to increase to 366 million by 2030. Diabetes Mellitus comprises a group of common metabolic disorders that share the phenotype of hyperglycemia, with an increase incidence worldwide. The Indian subcontinent has a higher prevalence of DM than any other region in the world, and two to three times the reported prevalence in western countries. Recent surveys say that diabetes is affecting 10-16% of urban population. The disease Madhumeha described in Ayurveda bears close resemblance to Diabetes Mellitus. Objectives: To evaluate the effect of Saptachakra Choorna in the management of Madhumeha w.s.r. to type 2 DM and to compare it with drug taken in the control group. Materials and Method: In the present study, two groups were taken each comprising of 20 patients who fulfilled the diagnostic and inclusion criteria. Subjects of group A were administered Saptachakra Choorna 6gms twice daily and subjects of group B were administered tablet Metformin 500 mg one tablet twice daily, both before food and for a period of 45 days. Observation and Results: In the present study, majority of the symptoms showed clinically significant improvement by Saptachakra Choorna and metformin 500 mg, however it was not statistically significant. In the glycemic parameters like FBS, PPBS, FUS and PPUS within the group administered Saptachakra Choorna 6 gms only FBS and PPBS showed significant improvement where as parameters like FUS and PPUS there was no much improvement and within the group administered tablet Metformin 500 mg significant improvement in all the parameters were observed. On comparing the results between the two groups, the group administered tablet Metformin 500 mg showed a better result than the group administered Saptachakra Choorna. Conclusion: By seeing overall improvement and applying Chi Square Test, tablet Metformin 500 mg showed a better result than Saptachakra Choorna.

2021 ◽  
Vol 4 (2) ◽  
pp. 511-516
Author(s):  
Eka Anita ◽  
Muhammad Taufik Daniel Hasibuan

Indonesia is the 7th country with the highest incidence of diabetes mellitus (DM) with 8.5 million. Data obtained at Aminah Hospital in 2020 from January to December there were 192 Type 2 DM patients being treated and 3659 patients receiving outpatient treatment. The family has a very important role in the health status of family members who suffer from chronic diseases such as diabetes mellitus. Family support can have a positive impact on compliance with care management in DM patients. The purpose of this study was to determine whether there was a relationship between family support and blood sugar control in type 2 DM patients undergoing treatment at Aminah Hospital. This research method uses descriptive correlation and the sample involved is 48 and to analyze the data using the chi square test. The results of this study showed that there was a significant relationship between family support and blood sugar control in type 2 DM patients with p = 0.000 or p <0.005. Family support is very important to influence blood sugar control and it is hoped that families always provide support to sick family members.   Abstrak Indonesia  merupakan  negara dengan urutan ke 7 dengan kejadian diabetes  melitus (DM)  tertinggi  yaitu dengan  jumlah  8,5  juta. Data yang didapat di RS Aminah pada tahun 2020 dari bulan Januari sampai Desember terdapat 192 pasien DM Tipe 2 yang dirawat dan 3659 pasien yang berobat jalan. Keluarga memiliki peran yang sangat penting terhadap status kesehatan pada anggota keluarga yang mengidap penyakit kronis seperti diabetes mellitus. Dukungan keluarga dapat memberikan dampak positif terhadap kepatuhan manajemen perawatan pada pasien DM. Tujuan penelitian ini untuk melihat ada tidaknya hubungan dukungan keluarga dan kontrol gula darah pada pasien DM tipe 2 yang menjalani perawatan di rumah sakit aminah. Metode penelitian ini menggunakan deskriptif korelasi dan sampel yang terlibat sebanyak 48 serta untuk menganalisis data menggunakan uji chi square. Hasil penelitian ini menunjukan ada hubungan yang signifikan antara dukungan keluarga dengan kontrol gula darah pasien DM tipe 2 dengan nilai p = 0,000 atau p<0,005. Dukungan keluarga sangat penting untuk mempengaruhi kontrol gula darah dan diharapkan keluarga selalu memberikan dukungan kepada anggota keluarga yang sakit.


2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Reza Ekatama Rajasa ◽  
Afriwardi Afriwardi ◽  
Setia Budi Zein

AbstrakAda banyak faktor yang mempengaruhi komplikasi pada pasien DM tipe 2, salah satunya adalah keteraturan berolahraga. Aktivitas fisik yang kurang akan  berisiko terjadinya hiperglikemia. Kondisi ini lambat laun akan menyebabkan kerusakan mikrovaskular dan makrovaskular. Olahraga yang teratur dapat membuat normal gula darah. Tujuan penelitian ini adalah meneliti lebih lanjut tentang hubungan keteraturan berolahraga terhadap komplikasi DM tipe 2. Penelitian ini dilakukan pada masyarakat yang berkunjung ke poliklinik RSUP Dr. M. Djamil Padang. Ini merupakan studi retrospektif dengan jumlah subjek 73 orang. Pengumpulan data responden dilakukan dengan wawancara dan rekam medis. Analisis statistik yang digunakan adalah uji chi-square.Hasil penelitian ini menunjukkan bahwa 65,8% responden menderita 3 atau lebih komplikasi (banyak), sedangkan 34,2% menderita kurang dari 3 komplikasi (sedikit). Kesimpulan studi ini adalah terdapat hubungan antara keteraturan berolahraga dengan komplikasi DM tipe 2.Kata kunci: keteraturan berolahraga, komplikasi DM tipe 2AbstractThere are many factors correlate to complications in  type 2 diabetes mellitus (DM) patients, one of them is exercise regularity. Lack of physical activity can lead to the hiperglycemia condition. It  could be the cause of  micovascular and macrovascular injuries. Exercise regularity can lead blood glucose toward normal. The objective of this study was to investigate the correlation of exercise regularity to the type 2 DM complications.The research was conducted to the  people who visit polyclynic of M. Djamil Hospital. It is a retrospective study with 73 subjek. Data collection was performed through interviews and using medical records. The statistical analysis was performed chi-square test.The result of this research found that 65.8% of respondent had many complication ( three or more), whereas 34.2% of had less than three complications. Analysis by chi square test, concluded that there was a significant relation between exercise regularity and complications of type 2 DM.Keywords: exercise regularity, complication of type II DM


2020 ◽  
Vol 8 (E) ◽  
pp. 574-577
Author(s):  
Rina Amelia ◽  
Juliandi Harahap ◽  
Novita Sari Harahap ◽  
Hendri Wijaya ◽  
Reni Asmara Ariga ◽  
...  

BACKGROUND: Sleep disturbance is one of the problems complained by diabetes mellitus (DM) patients. The decrease in sleep quality has an impact on not controlling blood glucose levels (BGL). AIM: The aim of the study was to analyze the effect of sleep quality on control BGLs of type 2 DM patients in Medan. METHODS: This study is analytic with a cross-sectional design. The study population was type 2 DM patients who came to the Medan Labuhan Primary Health Care with a total sample of 83 people, sample collection by consecutive sampling method (inclusion and exclusion criteria). Management data using the SPSS computer program and data analysis using the Chi-square test. RESULTS: The majority of patients were female (57.8%), the most age group was above 50 years (98.8%), with the highest duration of illnesses being above 5 years (77.1%), family history of suffering from DM was mothers with DM (36.1%), and mean of BGL was 215 mg/dl. The Chi-square test results showed a significant relationship between sleep quality and BGL of type 2 DM patients in Medan (p < 0.05), with an odds ratio of 4.3. CONCLUSION: Sleep quality affects blood sugar control in type 2 DM patients. The risk of increasing blood sugar due to sleep disorders is 4.3 times compared to DM patients who do not experience sleep disorders.


2020 ◽  
Vol 20 (4) ◽  
pp. 584-590 ◽  
Author(s):  
Shima Fathi ◽  
Shiva Borzouei ◽  
Mohammad Taghi Goodarzi ◽  
Jalal Poorolajal ◽  
Fatemeh Ahmadi-Motamayel

Background: Diabetes Mellitus (DM) is a progressive metabolic disorder. Objective: The aim of this study was to investigate the relationship between antioxidant and oxidative stress markers in the saliva of patients with type 2 DM and a healthy control group. Methods: In this study, 20 patients with diabetes and 20 healthy individuals were evaluated. Salivary antioxidants markers consisted of total antioxidant capacity (TAC), uric acid (UA), peroxidase and catalase. Oxidative stress markers included total oxidant status (TOS), malondealdehyde (MDA) and total thiol (SH). Sialochemical analysis was performed with spectrophotometric assay. All the statistical analyses were conducted using STATA software. Results: TAC decreased significantly in patients with diabetes. Although salivary UA and peroxidase were lower in patients with diabetes compared to the control group, the difference was not significant. Salivary catalase in patients with diabetes was significantly lower than that in the control group. MDA and TOS exhibited significantly higher levels in type 2 DM. SH levels were slightly higher in DM. Conclusions: According to the results of the present study, there were some changes in the salivary levels of some antioxidants and oxidative stress markers in patients with type 2 DM and could be measured as an indicator of serum changes..


2021 ◽  
Vol 45 (5) ◽  
pp. 312-316
Author(s):  
Mishra Neha Sanjeev ◽  
Harsimran Kaur ◽  
Sandeep Singh Mayall ◽  
Rishika ◽  
Ramakrishna Yeluri

Objective: To evaluate the effectiveness of placing a resorbable collagen barrier in impeding the extrusion of obturation material in primary molars undergoing resorption. Study design: All the 94 canals in 47 mandibular molars were allocated to 2 groups- Group ‘A’- 47 canals with collagen barrier (Test group) and Group ‘B’- 47 canals without collagen barrier (Control group) based on randomization protocol. Pulpectomy was performed and obturation of both test and control canals were radiographically assessed. Pearson’s chi – square test was applied to analyze the results. The significance level was predetermined at p &lt; 0.05. Results: Among the test group, 93.6% of the canals showed no extrusion while, 6.4% showed visible extrusion of the material outside the apex. In the control group, 83% showed no extrusion whereas 17% of the canals showed visible extrusion outside the apex. But no significant difference was noted (p&gt;0.05). Conclusion: The placement of resorbable collagen barrier in the apical third of the canal prevented the extrusion of obturating material beyond the apex in resorbing primary molars.


2005 ◽  
Vol 11 (3) ◽  
pp. 177-180 ◽  
Author(s):  
L. A. Lohankova ◽  
Yu. V. Kotovskaya ◽  
A. S. Milto ◽  
Zh. D. Kobalava

The structural and functional features of the microcirculatory heel (MCB) were studied in patients with arterial hypertension (AH) in relation to the presence or absence of type 1 diabetes mellitus (DM). Two hundred and twelve patients were examined. These included 110 patients with grades 1 and 2 arterial hypertension (AH) and type 2 DM, 82 patients with AH without type 2 DM, and 20 apparently healthy individuals. Laser Doppler flowmetry (LDF) was used to estimate basal blood flow, the loading test parameters characterizing the structural and functional status of MCB, and the incidence of hemodynamic types of microcirculation. Patients with AH concurrent with type 1 DM were found to have the following microcirculatory features: an increase in perfusion blood flow (microcirculation index, 8,8±1,8 perf. units versus 4,9±0,8 perf, units in patients with AH without DM and 6,7±0,9 perf. units in the control group), a drastic reduction in myogenic activity to 13,2±5,7 % versus 16,7±6,8 and 25,2±6,4 %, respectively, a decrease in vascular resistance, impairment of autoregulation, and low reserve capacities (reserve capillary blood flow was 197,8±31,6 % versus 429,9±82,01 % in the group of AH without DM and 302,8±50,1 % in the control group), a predominance of the hyperemic hemodynamic type (58,8 % in patients with AH and DM, 20,9 % in those with AH without DM, and 20,0 % in the controls). The specific features of the altered microcirculatory bed in patients with AH concurrent with type 2 DM were ascertained. These included the predominance of hyperemic microcirculation, impaired autoregulation. diminished microvascular resistance, and the low reserve capacities of the microcirculatory bed.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Rosliana Dewi ◽  
Fanny Dwi Agustina ◽  
Johan Budhiana ◽  
Syiva Dwi Fatmala

Diabetes mellitus (DM) can cause physical and psychological changes for sufferers. Psychological changes include changes in self-concept and depression. Psychological changes can be treated with nonpharmacological therapies, one of which is five-finger relaxation technique. The research aimed to reveal the effect of five-finger relaxation technique on depression experienced by type 2 DM patients. The five-finger relaxation technique is one of the generalist relaxation techniques by recalling pleasant experiences. This research is a quasi-experiment. Samples of this research were 34 respondents whom were selected using purposive sampling.  The intervention was carried out once a day for 3 consecutive days.  In order to measure depression, a valid and reliable questionnaire of Indonesian version of the Beck Depression Inventory (BDI) was employed.  Data were analyzed using the Wilcoxon Test and the Mann-Whitney Test. The results showed the was a decrease in depression in the control group (p-value of 0.008) and the intervention group (p-value of 0.000) and there were differences in depression in the control group and the intervention group (p-value of 0.000). It can be concluded that there is an effect of five-finger relaxation technique on depression in type 2 DM patients<em>.</em>


2021 ◽  
Vol 8 (1) ◽  
pp. 14-19
Author(s):  
Lukatul Khoiriyah ◽  
Ramli Effendi ◽  
Thia Oktiany

The level of family knowledge is a very important factor in the actions of families of people with Diabetes Mellitus, behavior based on knowledge will be easier to carry out than those not based on knowledge. Diabetes Mellitus is a disease that requires proper and immediate treatment efforts because it can cause complications such as heart disease, kidney failure, and damage to the nervous system. One way to overcome the effects of Type 2 Diabetes Mellitus is by applying a diet. This study aims to determine the relationship between the level of family knowledge with efforts to prevent complications of type 2 diabetes mellitus in the work area of Babakan Puskesmas, Cirebon Regency. This research method uses descriptive correlational, this research uses cross section research. The population is all families with type 2 Diabetes Mellitus in the work area of Babakan Puskesmas in Cirebon Regency as many as 144 respondents and sampling using Purposive Sampling obtained 60 respondents. The instruments used were questionnaire sheets, and data analysis using chi-square test that is the significance value α = 0.1. The results of the above study indicate between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in getting p-value = 0.04, because the p-value of 0.04 <0.1 then Ho is rejected and Ha is accepted which means there is a relationship between the level of family knowledge and prevention of complications of type 2 diabetes mellitus in the work area of Babakan Health Center, Cirebon Regency.


2012 ◽  
Vol 56 (5) ◽  
pp. 285-290 ◽  
Author(s):  
Serdal Korkmaz ◽  
Abdulkerim Yilmaz ◽  
Gürsel Yildiz ◽  
Fatih Kiliçli ◽  
Serhat Içağasioğlu

OBJECTIVE: The rate of reduction of nocturnal blood pressure (NBP) is lesser than normal in patients with type 2 diabetes mellitus (type 2 DM). Hyperhomocysteinemia (HHC) disrupts vascular structure and function, no matter the underlying causes. The risk of development of vascular disease is greater in diabetic patients with hyperhomocysteinemia than in patients with normal homocystein levels. The aim of the study was to investigate whether there are differences of homocystein levels in dipper and non-dippers patients with type 2 DM. SUBJECTS AND METHODS: We compared 50 patients (33 females, 17 males) with type 2 DM and 35 healthy individuals (18 females, 17 males ) in a control group. Ambulatory blood pressure monitoring (ABPM) was performed and homocysteine levels were measured in all patients. RESULTS: We found that the percentage of non-dipper pattern was 72% in patients with type 2 DM and 57% in control group. In diabetic and control individuals, homocystein levels were higher in non-dipper (respectively 13.4 ± 8.1 µmol/L and 11.8 ± 5 µmol/L) than in dipper subjects (respectively, 11.8 ± 5.8 µmol/L and 10.1 ± 4.2 µmol/L), but there was no significant difference between the two groups (respectively, p = 0.545, p = 0.294). CONCLUSION: In both groups, homocystein levels were higher in non-dipper than in dipper participants, but there was no significant difference between the groups. High homocystein levels and the non-dipper pattern increases cardiovascular risk. Therefore, the relationship between nocturnal blood pressure changes and homocystein levels should be investigated in a larger study.


2016 ◽  
Vol 26 (2) ◽  
pp. 241-253 ◽  
Author(s):  
Mahdi Moshki ◽  
Atefeh Dehnoalian ◽  
Ali Alami

This study sought to assess the effect of precede–proceed model on preventive behaviors for type 2 diabetes mellitus (DM) in high-risk individuals. In this semi-experimental study, 164 high-risk individuals for type 2 DM were selected and were randomly divided into two groups of intervention and control ( n = 85). Educational intervention was performed as a single session face-to-face instruction for 1.5 hr for the intervention group participants. Data were collected before (baseline) and immediately and 1 month after the intervention in the two groups. The mean score of predisposing (knowledge) factors ( p = .001), reinforcing factors ( p = .001), and enabling factors ( p = .02) were significantly different at baseline and 1 month after the intervention in the intervention group compared with the control group ( p < .05). A significant improvement occurred in the nutritional habits of high-risk participants in the intervention group at 1 month after the intervention compared with controls ( p = .001). The precede–proceed model can be effective for promoting the preventive behaviors for type 2 DM in high-risk individuals.


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