scholarly journals Outcomes of Preserving the Hypertrophic Arachnoid Membrane in the Brain–meningioma Interface: Long-term Follow-up

Author(s):  
Yoko NAKASU ◽  
Koichi MITSUYA ◽  
Satoshi NAKASU ◽  
Shoichi DEGUCHI ◽  
Nakamasa HAYASHI
2012 ◽  
Vol 114 (9) ◽  
pp. 1217-1221 ◽  
Author(s):  
Yoshiko Okita ◽  
Yoshitaka Narita ◽  
Yasuji Miyakita ◽  
Makoto Ohno ◽  
Shintaro Fukushima ◽  
...  

CHEST Journal ◽  
1992 ◽  
Vol 101 (1) ◽  
pp. 278-279 ◽  
Author(s):  
Charlotte Malasky ◽  
Lee B. Reichman

CNS Oncology ◽  
2016 ◽  
Vol 5 (1) ◽  
pp. 31-40 ◽  
Author(s):  
Natalie Pulenzas ◽  
Saurabh Ray ◽  
Liying Zhang ◽  
Rachel McDonald ◽  
David Cella ◽  
...  

1994 ◽  
Vol 6 (2) ◽  
pp. 97-106 ◽  
Author(s):  
M. Ząbek ◽  
W. Mazurowski ◽  
J. Dymecki ◽  
J. Stelmachów ◽  
E. Zawada

2006 ◽  
Vol 105 (5) ◽  
pp. 736-738 ◽  
Author(s):  
Pasquale Gallina ◽  
Anna Maria Buccoliero ◽  
Furio Mariotti ◽  
Pasquale Mennonna ◽  
Nicola di Lorenzo

Object Oncocytic meningioma has recently been recognized as a distinct morphological variant of intracranial meningothelial neoplasms, and only a few cases have been reported in the literature. The first description of this lesion, which was based on data in six cases, revealed a potentially aggressive nature with a tendency to infiltrate the brain and to recur. However, the true behavior of, and the long-term follow-up data for, such lesions must still be outlined. Methods The authors report on five cases of intracranial oncocytic meningiomas. On neuroimaging, the lesions showed the characteristic features of common meningiomas. All patients underwent gross-total removal of the mass together with the adjacent dura mater. No additional treatments were administered. Histologically, the tumors were composed of sheets, nests, and cords of large polygonal neoplastic cells with finely granular cytoplasm. Necrosis was absent in all cases. Mitosis was also absent or exceedingly rare, and no brain cortex infiltration was observed. The follow up ranged from 6 to 54 months (mean 32.4 months). At the last follow-up evaluation, all patients were asymptomatic and magnetic resonance imaging examinations demonstrated no evidence of tumor recurrence. Conclusions Data in the presented cases did not confirm a previously described propensity to aggressiveness in this meningioma subtype. In fact, the histological features as well as the long-term favorable clinical course may suggest benign behavior of such neoplasms, as in the common forms of meningiomas.


1982 ◽  
Vol 22 (2) ◽  
pp. 125-132 ◽  
Author(s):  
Hideaki NUKUI ◽  
Osamu MIYAGI ◽  
Junpei TAMADA ◽  
Shigeru MITSUKA ◽  
Jun-ichi KAWAFUCHI

2012 ◽  
Vol 35 (6) ◽  
pp. 1332-1337 ◽  
Author(s):  
Vít Herynek ◽  
Dita Wagnerová ◽  
Irena Hejlová ◽  
Monika Dezortová ◽  
Milan Hájek

2013 ◽  
Vol 11 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Amit Singla ◽  
Jill E. Brace O'Neill ◽  
Edward Smith ◽  
R. Michael Scott

Object The authors undertook this study to determine the clinical course and long-term outcomes in pediatric patients who developed cavernous malformations of the brain following treatment for acute lymphocytic leukemia (ALL). Methods They reviewed the senior author's database of surgically treated cavernous malformations of the brain to identify those patients whose cavernous malformations developed after cranial radiation during treatment for ALL. The medical records of these patients were reviewed to determine their clinical presentation, radiological findings, and outcome at long-term follow-up. Results Five patients fulfilled the specified criteria over a 23-year period. At the time of ALL diagnosis, they were all 4–5 years old. The cerebral cavernous malformations developed 2–8 years after cranial radiation, and 4 of the 5 patients presented with neurological symptoms, which ranged from focal deficits to seizures. Two patients required a second craniotomy, one from lesion recurrence possibly due to incomplete resection, and another for a second cavernous malformation, which developed at another site 6 years after the initial malformation was excised. Long-term follow-up of 2, 10, 11, 11, and 17 years has revealed no additional lesion development or recurrence. Conclusions Symptomatic cavernous malformations of the brain may develop several years after chemotherapy and cranial radiation treatment for ALL, and the clinical course of these cavernous malformations may be more aggressive than that of the typical post-radiation lesions seen in other conditions. Long-term clinical and imaging monitoring is recommended for children who have undergone treatment for ALL. Craniotomy for excision of the malformations appears to convey long-term protection from repeat hemorrhage and accumulating neurological deficits.


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