scholarly journals Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation

2021 ◽  
Author(s):  
Tsukasa HIRANO ◽  
Takeshi MIKAMI ◽  
Shoto YAMADA ◽  
Hiroshi NAGAHAMA ◽  
Rei ENATSU ◽  
...  
Keyword(s):  
Carotid Ligation ◽  
Early Seizure

scholarly journals A Long-term Follow-up Study of Common Carotid Ligation for Posterior Communicating Aneurysms

1982 ◽  
Vol 22 (1) ◽  
pp. 43-50
Author(s):  
Ryuzo SHIOBARA ◽  
Shigeo TOYA ◽  
Youichi IISAKA ◽  
Kiyoshi ICHIKIZAKI ◽  
Shigemaru MIKOUCHI ◽  
...  
Keyword(s):  
Follow Up Study ◽  
Carotid Ligation ◽  
Long Term Follow Up

scholarly journals Strain-Related Differences in Mouse Neonatal Hypoxia-Ischemia

2018 ◽  
Vol 40 (5-6) ◽  
pp. 490-496 ◽  
Author(s):  
R. Ann Sheldon ◽  
Christine Windsor ◽  
Donna M. Ferriero
Keyword(s):  
Brain Injury ◽  
Mouse Model ◽  
Strain Differences ◽  
Artery Occlusion ◽  
Carotid Artery Occlusion ◽  
Cresyl Violet ◽  
Posterior Cortex ◽  
Carotid Ligation ◽  
Hypoxia Ischemia ◽  
Cd1 Mice

Neonatal hypoxic-ischemic brain injury is commonly studied by means of the Vannucci procedure in mice or rats (unilateral common carotid artery occlusion followed by hypoxia). Previously, we modified the postnatal day 7 (P7) rat procedure for use in mice, and later demonstrated that genetic strain strongly influences the degree of brain injury in the P7 mouse model of hypoxia-ischemia (HI). Recently, the P9 or P10 mouse brain was recognized as the developmental equivalent of a term neonatal human brain, rather than P7. Consequently, the Vannucci procedure has again been modified, and a commonly used protocol employs 10% oxygen for 50 min in C57Bl/6 mice. Strain differences have yet to be described for the P9/P10 mouse model. In order to determine if the strain differences we previously reported in the P7 mouse model are present in the P9 model, we compared 2 commonly used strains, CD1 and C57Bl/6J, in both the P7 (carotid ligation [in this case, right] followed by exposure to 8% oxygen for 30 min) and P9 (carotid ligation [in this case left] followed by exposure to 10% oxygen) models of HI. Experiments using the P7 model were performed in 2001–2012 and those using the P9 model were performed in 2012–2016. Five to seven days after the HI procedure, mice were perfused with 4% paraformaldehyde, their brains were sectioned on a Vibratome (50 µm) and alternate sections were stained with Perl’s iron stain or cresyl violet. Brain sections were examined microscopically and scored for the degree of injury. Since brains in the P7 group had been scored previously with a slightly different system, they were reanalyzed using our current scoring system which scores injury in 11 regions: the anterior, middle, and posterior cortex; the anterior, middle, and posterior striatum; CA1, CA2, CA3, and the dentate gyrus of the hippocampus and thalamus, on a scale from 0 (none) to 3 (cystic infarct) for a total score of 0–33. Brains in the P9 group were scored with the same system. Given the same insult, the P7 CD1 mice had greater injury than the C57Bl/6J mice, which agrees with our previous findings. The P9 CD1 mice also had greater injury than the C57Bl/6J mice. This study confirms that CD1 mice are more susceptible to injury than C57Bl/6J mice and that strain selection is important when using mouse models of HI.

Aneurysm-induced third nerve palsy

1972 ◽  
Vol 36 (5) ◽  
pp. 548-551 ◽  
Author(s):  
Iftikhar A. Raja
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Functional Recovery ◽  
Poor Prognosis ◽  
Nerve Palsy ◽  
Nerve Function ◽  
Content Type ◽  
Third Nerve Palsy ◽  
Carotid Ligation ◽  
Third Nerve ◽  
Fine Print

✓ Forty-two patients with aneurysm-induced third nerve palsy are described. After carotid ligation, 58% showed satisfactory and 42% unsatisfactory functional recovery. In some patients the deficit continued to increase even after carotid ligation. Early ligation provided a better chance of recovery of third nerve function. Patients in whom third nerve palsy began after subarachnoid hemorrhage had a poor prognosis. No relationship was noted between the size of the aneurysm and the recovery of third nerve function.

Arterial spin-labeling magnetic resonance imaging for diagnosis of early seizure after stroke

2015 ◽  
Vol 354 (1-2) ◽  
pp. 127-128 ◽  
Author(s):  
Yosuke Miyaji ◽  
Yuichi Kawabata ◽  
Hideto Joki ◽  
Shunsuke Seki ◽  
Kentaro Mori ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Arterial Spin Labeling ◽  
Spin Labeling ◽  
Resonance Imaging ◽  
Early Seizure

scholarly journals Blunt innominate artery trauma requiring repair and carotid ligation

2017 ◽  
Vol 12 ◽  
pp. 24-27 ◽  
Author(s):  
Kathryn L. Howe ◽  
Mina Guirgis ◽  
Grant Woodman ◽  
F. Victor Chu ◽  
M.J. Cooper ◽  
...  
Keyword(s):  
Innominate Artery ◽  
Carotid Ligation

On the Influence of a Monolateral Carotid Ligation Upon the Formation of Radiation Cataract in Rats (With Colour Plate I)

1974 ◽  
Vol 6 (2-4) ◽  
pp. 175-182 ◽  
Author(s):  
H.-R. Koch ◽  
F. Kremer ◽  
E. Linnér ◽  
O. Hockwin ◽  
H. Kaufmann ◽  
...  
Keyword(s):  
Carotid Ligation ◽  
Colour Plate ◽  
Radiation Cataract

Early Seizure Detection

Epilepsy ◽  
2010 ◽  
pp. 573-588
Author(s):  
Christophe Jouny ◽  
Piotr Franaszczuk ◽  
Gregory Bergey
Keyword(s):  
Seizure Detection ◽  
Early Seizure

Non-parametric early seizure detection in an animal model of temporal lobe epilepsy

2008 ◽  
Vol 5 (1) ◽  
pp. 85-98 ◽  
Author(s):  
Sachin S Talathi ◽  
Dong-Uk Hwang ◽  
Mark L Spano ◽  
Jennifer Simonotto ◽  
Michael D Furman ◽  
...  
Keyword(s):  
Animal Model ◽  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Seizure Detection ◽  
Early Seizure ◽  
Non Parametric
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