scholarly journals Predictive Factors of Antiparkinsonian Drug Reduction after Subthalamic Stimulation for Parkinson’s Disease

2019 ◽  
Vol 59 (9) ◽  
pp. 331-336
Author(s):  
Kazuhiro SAMURA ◽  
Yasushi MIYAGI ◽  
Minako KAWAGUCHI ◽  
Fumiaki YOSHIDA ◽  
Tsuyoshi OKAMOTO ◽  
...  
Brain ◽  
2002 ◽  
Vol 125 (3) ◽  
pp. 575-583 ◽  
Author(s):  
M. L. Welter ◽  
J. L. Houeto ◽  
S. Tezenas du Montcel ◽  
V. Mesnage ◽  
A. M. Bonnet ◽  
...  

2004 ◽  
Vol 31 (S 1) ◽  
Author(s):  
B Haslinger ◽  
K Kalteis ◽  
F Alesch ◽  
H Boecker ◽  
AO Ceballos-Baumann

Motor Control ◽  
2004 ◽  
Vol 8 (4) ◽  
pp. 484-499 ◽  
Author(s):  
Jay L. Alberts ◽  
Christopher M. Elder ◽  
Michael S. Okun ◽  
Jerrold L. Vitek

2018 ◽  
Vol 11 (4) ◽  
pp. 867-874 ◽  
Author(s):  
Haidar Salimi Dafsari ◽  
Luisa Weiß ◽  
Monty Silverdale ◽  
Alexandra Rizos ◽  
Prashanth Reddy ◽  
...  

2020 ◽  
Author(s):  
Yvan Vachez ◽  
Marie Bahout ◽  
Robin Magnard ◽  
Pierre-Maxime David ◽  
Carole Carcenac ◽  
...  

ABSTRACTApathy is frequently reported in Parkinson’s disease (PD) patients under subthalamic nucleus deep brain stimulation (STN-DBS). The prevailing clinical view for apathy following STN-DBS is the reduction of dopaminergic medication. However, few clinical reports and recent experimental data suggested the pathogenicity of bilateral STN-DBS on motivation, challenging the leading opinion. Here, we investigate whether bilateralism of STN-DBS influences apathy outcome after STN-DBS, combining pre-clinical and clinical approaches. We assess the motivational effects of chronic unilateral STN-DBS in rats in the exact same conditions having highlighted a loss of motivation under bilateral STN-DBS. Clinical data are obtained by the follow-up of a cohort of parkinsonian patients undergoing unilateral STN-DBS and coming from the clinical center that described apathy related to bilateral STN-DBS itself. Despite an acute effect, which fades rapidly, unilateral STN-DBS did not induce a loss of motivation reminiscent to apathy in rats. In patients, apathy did not increase between the preoperative and the post-operative assessment. Together, those data demonstrate that bilateral but not unilateral STN-DBS can induce a loss of motivation in both rats and patients. This constitutes another evidence of the role of STN-DBS itself for apathy in PD.


2020 ◽  
Vol 7 (06) ◽  
pp. 4832-4836
Author(s):  
M. Kovacheva Slavova ◽  
Magdalena Aleksieva ◽  
Victoria Ilieva ◽  
Plamen Gecov ◽  
Borislav Vladimirov

Benign esophageal strictures are uncommon and their management remains challenging. Herein, we present a rare both functional and organic esophageal stricture in a patient with Parkinson’s disease and reflux esophagitis. The patient was diagnosed with severe complex stricture in the distal part of the esophagus, requiring surgical treatment. We performed subtotal esophageal resection and Ivor-Lewis gastroesophagoplasty. The successful management of antiparkinsonian drug therapy with adequate parenteral substitution in the early postoperative period is of great importance to avoid any further complications.


2013 ◽  
Vol 6 (5) ◽  
pp. 740-745 ◽  
Author(s):  
Tereza Serranová ◽  
Tomáš Sieger ◽  
Petr Dušek ◽  
Filip Růžička ◽  
Dušan Urgošík ◽  
...  

2014 ◽  
Vol 4 (3) ◽  
pp. 413-420 ◽  
Author(s):  
Agnès Annic ◽  
Caroline Moreau ◽  
Julia Salleron ◽  
David Devos ◽  
Arnaud Delval ◽  
...  

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