scholarly journals Surgical Technique and Outcome of Extensive Frontal Lobectomy for Treatment of Intracable Non-lesional Frontal Lobe Epilepsy

2020 ◽  
Vol 60 (1) ◽  
pp. 17-25
Author(s):  
Sachiko HIRATA ◽  
Michiharu MORINO ◽  
Shunsuke NAKAE ◽  
Takahiro MATSUMOTO
Keyword(s):  
Surgical Technique ◽  
Frontal Lobe ◽  
Frontal Lobe Epilepsy ◽  
Frontal Lobectomy

scholarly journals Epilepsy Surgery in the Frontal Lobe: Terra Incognita or New Frontier?

2007 ◽  
Vol 7 (4) ◽  
pp. 98-99 ◽  
Author(s):  
John W. Miller
Keyword(s):  
Frontal Lobe ◽  
Epilepsy Surgery ◽  
Prognostic Indicators ◽  
P Value ◽  
Frontal Lobe Epilepsy ◽  
Seizure Outcome ◽  
Seizure Freedom ◽  
Ratio Test ◽  
Longitudinal Outcome ◽  
Frontal Lobectomy

Surgical Outcome and Prognostic Factors of Frontal Lobe Epilepsy Surgery. Jeha LE, Najm I, Bingaman W, Dinner D, Widdess-Walsh P, Luders H. Brain 2007;130(Pt 2):574–584. Epub 2007 Jan 5. Frontal lobe epilepsy (FLE) surgery is the second most common surgery performed to treat pharmacoresistant epilepsy. Yet, little is known about long-term seizure outcome following frontal lobectomy. The aim of this study is to investigate the trends in longitudinal outcome and identify potential prognostic indicators in a cohort of FLE patients investigated using modern diagnostic techniques. We reviewed 70 patients who underwent a frontal lobectomy between 1995 and 2003 (mean follow-up 4.1 ± 3 years). Data were analysed using survival analysis and multivariate regression with Cox proportional hazard models. A favourable outcome was defined as complete seizure-freedom, allowing for auras and seizures restricted to the first post-operative week. The estimated probability of complete seizure-freedom was 55.7% [95% confidence interval (CI) = 50–62] at 1 post-operative year, 45.1% (95% CI = 39–51) at 3 years, and 30.1% (95% CI = 21–39) at 5 years. Eighty per cent of seizure recurrences occurred within the first 6 post-operative months. Late remissions and relapses occurred, but were rare. After multivariate analysis, the following variables retained their significance as independent predictors of seizure recurrence: MRI-negative malformation of cortical development as disease aetiology [risk ratio (RR) = 2.22, 95% CI = 1.40–3.47], any extrafrontal MRI abnormality (RR = 1.75, 95% CI = 1.12–2.69), generalized/non-localized ictal EEG patterns (RR = 1.83, 95% CI = 1.15–2.87), occurrence of acute post-operative seizures (RR = 2.17, 95% CI = 1.50–3.14) and incomplete surgical resection (RR = 2.56, 95% CI = 1.66–4.05) (log likelihood-ratio test P-value < 0.0001). More than half of patients in favourable prognostic categories were seizure-free at 3 years, and up to 40% were seizure-free at 5 years, compared to <15% in those with unfavourable outcome predictors. These data underscore the importance of appropriate selection of potential surgical candidates.

scholarly journals Tailoring of Cortical Excisions for Frontal Lobe Epilepsy

1991 ◽  
Vol 18 (S4) ◽  
pp. 606-610 ◽  
Author(s):  
Theodore Rasmussen
Keyword(s):  
Frontal Cortex ◽  
Frontal Lobe ◽  
Marked Reduction ◽  
Temporal Cortex ◽  
Frontal Lobe Epilepsy ◽  
Frontal Lobectomy

ABSTRACT:Follow-up data of 2 to 49 years' duration are presented on 257 patients with cortical excisions for non-tumoral frontal lobe epilepsy. Twenty-six percent have become and remained seizure free. Another 30% have had a marked reduction of seizure tendency. Thus a total of 56% have had a long term complete or marked reduction of seizure tendency after the cortical resection. The cortical resections were classified into 5 regional categories. Forty-seven percent of patients with anterior frontal resections were in the seizure free category, as were 35% of patients with excisions limited to the convexity cortex and 32% of patients with maximal or near maximal frontal lobectomy. Only 18% of patients with frontal parasaggital excisions were in the seizure free category, and 10% of the patients who had excision of frontal cortex plus limited excision of adjacent central and/or temporal cortex.

Anterior Callosotomy Added to Frontal Lobectomy in Frontal Lobe Epilepsy

1995 ◽  
pp. 191-200
Author(s):  
N. Giard ◽  
I. Rouleau ◽  
A. Bouthillier ◽  
G. Bouvier ◽  
J. M. Saint-Hilaire
Keyword(s):  
Frontal Lobe ◽  
Frontal Lobe Epilepsy ◽  
Frontal Lobectomy

Frontal Lobe Decortication (Frontal Lobectomy with Ventricular Preservation) in Epilepsy—Part 1: Anatomic Landmarks and Surgical Technique

2017 ◽  
Vol 98 ◽  
pp. 347-364 ◽  
Author(s):  
Hung Tzu Wen ◽  
Leila Maria Da Róz ◽  
Albert L. Rhoton ◽  
Luiz Henrique Martins Castro ◽  
Manoel Jacobsen Teixeira
Keyword(s):  
Surgical Technique ◽  
Frontal Lobe ◽  
Anatomic Landmarks ◽  
Frontal Lobectomy

Presurgical Evaluation in Magnetic Resonance Image-Negative Frontal Lobe Epilepsy

2014 ◽  
Vol 45 (S 01) ◽  
Author(s):  
I. Borggräfe ◽  
C. Vollmar ◽  
A. Lösch ◽  
B. Ertl-Wagner ◽  
L. Gerstl ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Frontal Lobe ◽  
Magnetic Resonance Image ◽  
Frontal Lobe Epilepsy ◽  
Presurgical Evaluation

scholarly journals Mirror writing in a patient with frontal lobe epilepsy

2021 ◽  
Vol 9 (5) ◽  
Author(s):  
Yethindra Vityala ◽  
Tatiana Galako ◽  
Aliya Kadyrova ◽  
Elmira Mamytova ◽  
Anara Toktomametova ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Frontal Lobe Epilepsy ◽  
Mirror Writing

scholarly journals Different Effects of Antiepileptic Drugs on Initiation and Propagation of Ictal Discharges in a Case of Frontal Lobe Epilepsy

Epilepsia ◽  
1998 ◽  
Vol 39 (S5) ◽  
pp. 81-81
Author(s):  
Youji Takeda ◽  
Fumihiro Nakamura ◽  
Masumi Ito ◽  
Yuji Itaichi ◽  
Yoshirou Hayashi ◽  
...  
Keyword(s):  
Frontal Lobe ◽  
Antiepileptic Drugs ◽  
Frontal Lobe Epilepsy ◽  
Initiation And Propagation

scholarly journals Abnormal self-location and vestibular vertigo in a patient with right frontal lobe epilepsy

2010 ◽  
Vol 17 (2) ◽  
pp. 289-292 ◽  
Author(s):  
Christophe Lopez ◽  
Lukas Heydrich ◽  
Margitta Seeck ◽  
Olaf Blanke
Keyword(s):  
Frontal Lobe ◽  
Frontal Lobe Epilepsy ◽  
Vestibular Vertigo
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