scholarly journals 11. In Some Aspect of Electrical Stimulation of the Ventrolateral Nucleus and the Centromedian of the Human Thalamus

1967 ◽  
Vol 9 ◽  
pp. 285b-286
Author(s):  
Akira NISHIMOTO ◽  
Keizo MATSUMOTO ◽  
Takashi OHMOTO
1992 ◽  
Vol 263 (1) ◽  
pp. H198-H207 ◽  
Author(s):  
J. H. Jiao ◽  
P. G. Guyenet ◽  
A. J. Baertschi

The purpose of these studies was to investigate whether the central nervous system (CNS) can modulate the plasma level of atrial natriuretic factor (ANF). In anesthetized, spontaneously breathing rats, electrical stimulation was stereotaxically applied bilaterally to four medullary nuclei: 1) the rostral nucleus of the solitary tract (rNTS), 2) the intermediate portion of the NTS (iNTS), 3) the ventrolateral nucleus ambiguus (NA) 0.3 mm rostral to obex, and 4) the rostral ventrolateral medulla (RVL). Electrical stimulation of the rNTS and RVL caused a 55 +/- 18% (P less than 0.025, n = 6) and 187 +/- 80% (P less than 0.001, n = 5) increase in plasma ANF, respectively, compared with baseline (56-88 pg/ml), whereas sham stimulations had no effect on plasma ANF release. In contrast, electrical stimulation of the iNTS and the NA elicited a 35 +/- 6 (P less than 0.01, n = 7) and 31 +/- 6% (P less than 0.05, n = 5) decrease in plasma ANF, respectively. In artificially ventilated rats, unilateral electrical stimulation of the RVL induced a 94 +/- 39 (left RVL, n = 6, P less than 0.01) and 186 +/- 68% (right RVL, P less than 0.01, n = 5) increase in plasma ANF over baseline. Unilateral microinjection of L-glutamate into RVL also resulted in a 81 +/- 23% (n = 9, P less than 0.01) increase in plasma ANF compared with baseline and vehicle control injections. These results suggest that activation of the central sympathetic system potently stimulates the secretion of cardiac ANF.


2019 ◽  
Author(s):  
Emilia Toth ◽  
Ganne Chaitanya ◽  
Sandipan Pati

AbstractDirect electrical stimulation (DES) of the cortex is a clinically indispensable brain mapping technique that provides reliable information about the distribution of eloquent cortex and its connectivity to the white matter bundles. Here we present a technical report on mapping the short latency cortical responses to stimulation of the ventral anterior nucleus of human thalamus. Reliable downstream responses were noted in the regions connected to the ventral anterior nucleus i.e. superior and inferior frontal gyri, supplementary motor area and limbic substructures (cingulate gyrus and hippocampus).


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