scholarly journals Radiation-Induced World Health Organization Grade II Meningiomas in Young Patients Following Prophylactic Cranial Irradiation for Acute Lymphoblastic Leukemia in Childhood

2012 ◽  
Vol 52 (4) ◽  
pp. 224-228 ◽  
Author(s):  
Keiko ODA ◽  
Taku SATO ◽  
Tadashi WATANABE ◽  
Masahiro ICHIKAWA ◽  
Eiji ITO ◽  
...  
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
World Health Organization ◽  
Lymphoblastic Leukemia ◽  
Young Patients ◽  
Cranial Irradiation ◽  
Prophylactic Cranial Irradiation ◽  
World Health ◽  
Radiation Induced ◽  
Grade Ii ◽  
Health Organization

scholarly journals BCR-ABL1–like B-Acute Lymphoblastic Leukemia/Lymphoma: A Comprehensive Review

2019 ◽  
Vol 144 (2) ◽  
pp. 150-155 ◽  
Author(s):  
Sarika Jain ◽  
Anu Abraham
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
World Health Organization ◽  
Kinase Inhibitors ◽  
Lymphoblastic Leukemia ◽  
World Health ◽  
Comprehensive Review ◽  
The World ◽  
Health Organization ◽  
Stimulating Factor

Context.— In the 2016 update of the World Health Organization (WHO) classification of hematopoietic neoplasms, BCR-ABL1–like B-acute lymphoblastic leukemia/lymphoma (B-ALL) is added as a new provisional entity that lacks the BCR-ABL1 translocation but shows a pattern of gene expression very similar to that seen in B-ALL with BCR-ABL1. Objective.— To review the kinase-activating alterations and the diagnostic approach for BCR-ABL1–like B-ALL. Data Sources.— We provide a comprehensive review of BCR-ABL1–like B-ALL based on recent literature and the 2016 update of the World Health Organization classification of hematopoietic neoplasms. Conclusions.— Several types of kinase-activating alterations (fusions or mutations) are identified in BCR-ABL1–like B-ALL. The main categories are alterations in the ABL class family of genes, encompassing ABL1, ABL2, PDGFRB, PDGFRA (rare), and colony-stimulating factor 1 receptor (CSF1R) fusions, or the JAK2 class family of genes, encompassing alterations in JAK2, CRLF2, EPOR, and other genes in this pathway. These alterations determine the sensitivity to tyrosine kinase inhibitors. As a wide variety of genomic alterations are included in this category, the diagnosis of BCR-ABL1–like B-ALL is extremely complex. Stepwise algorithms and comprehensive unbiased testing are the 2 ways to approach the diagnosis of BCR-ABL1–like B-ALL.

scholarly journals Acute Lymphoblastic Leukemia, Classification, Clinical features and Diagnosis

2020 ◽  
Vol 19 (2) ◽  
pp. 59-65
Author(s):  
Fatimah Kadhim Ibrahim AL- Mahdawi ◽  
◽  
Mazin Razooqi Mohammed
Keyword(s):  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
World Health Organization ◽  
Acute Lymphocytic Leukemia ◽  
Lymphoblastic Leukemia ◽  
White Blood Cells ◽  
Lymphocytic Leukemia ◽  
World Health ◽  
The World ◽  
Health Organization

Background: Leukemias are classified as lymphoid or myeloid, dependent on the type of stem cell that is affected. In addition, leukemia is classified as chronic or acute. Acute leukemia is a production of bone marrow-derived immature cells (blasts), include solid organs or peripheral blood. The FAB Cooperative Group original classification scheme proposed to divide1 ALL into three subtypes (L1 - L3). Currently, the world health organization (WHO), modify FAB classification depending on immunophenotype. Symptoms presence of anemia, splenomegaly, and thrombocytopenia, and those are naturally present at diagnosis, indicating the degree to which leukemic lymphoblasts have replaced the bone marrow and the first mark to an ALL diagnosis is typically an abnormal complete blood count result. Objective: To introduce causes of acute lymphocytic leukemia, recent classification methods, diagnosis, and symptoms and diagnosis. Conclusion: Acute lymphocytic leukemia occurs due to a defect in the bone marrow and is classified into several types. The most important classification by the World Health Organization is depending on immunophenotype. The main symptoms are the increase in white blood cells with anemia and thrombocytopenia. Keywords: Acute Lymphoblastic Leukemia, Blood

Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas

2006 ◽  
Vol 60 (3) ◽  
pp. 380-383 ◽  
Author(s):  
Johan Pallud ◽  
Emmanuel Mandonnet ◽  
Hugues Duffau ◽  
Michèle Kujas ◽  
Rémy Guillevin ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
World Health Organization ◽  
Growth Rates ◽  
Prognostic Value ◽  
World Health ◽  
Resonance Imaging ◽  
Grade Ii ◽  
Health Organization

Differentiating Diffuse World Health Organization Grade II and IV Astrocytomas With Ex Vivo Magnetic Resonance Spectroscopy

Neurosurgery ◽  
2013 ◽  
Vol 72 (2) ◽  
pp. 186-195 ◽  
Author(s):  
Riyas Vettukattil ◽  
Michel Gulati ◽  
Torill E. Sjøbakk ◽  
Asgeir S. Jakola ◽  
Nadja A.M. Kvernmo ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
World Health Organization ◽  
Ex Vivo ◽  
World Health ◽  
Resonance Spectroscopy ◽  
Grade Ii ◽  
Health Organization

Revisiting Adjuvant Radiotherapy After Gross Total Resection of World Health Organization Grade II Meningioma

2017 ◽  
Vol 103 ◽  
pp. 655-663 ◽  
Author(s):  
Christopher S. Graffeo ◽  
Heather E. Leeper ◽  
Avital Perry ◽  
Joon H. Uhm ◽  
Daniel J. Lachance ◽  
...  
Keyword(s):  
World Health Organization ◽  
Adjuvant Radiotherapy ◽  
World Health ◽  
Gross Total Resection ◽  
Total Resection ◽  
Grade Ii ◽  
Health Organization
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