scholarly journals 37. On the Relationship between the Mode of Stimulation of Cortical Motor Area and Spinal Reflex Activity

1963 ◽  
Vol 5 (0) ◽  
pp. 69a-69
Author(s):  
Jiro TATSUNO ◽  
Utaka MATSUMOTO
Brain ◽  
1886 ◽  
Vol 9 (1) ◽  
pp. 144-144
Author(s):  
VICTOR HORSLEY

1999 ◽  
Vol 110 (5) ◽  
pp. 806-812 ◽  
Author(s):  
M Oliveri ◽  
F Brighina ◽  
V La Bua ◽  
D Buffa ◽  
A Aloisio ◽  
...  

2014 ◽  
Vol 34 (1) ◽  
pp. 93-98 ◽  
Author(s):  
Chun-yong Li ◽  
Xue-zhu Song ◽  
Li-xin Han ◽  
Qi Xie ◽  
Jun Wang ◽  
...  

2014 ◽  
Vol 41 (1) ◽  
pp. 97-108 ◽  
Author(s):  
Yoko Yazaki-Sugiyama ◽  
Shin Yanagihara ◽  
Patrick M. Fuller ◽  
Michael Lazarus

2016 ◽  
Vol 29 (3) ◽  
pp. 395-404 ◽  
Author(s):  
Elisa Kallioniemi ◽  
Petro Julkunen

Neurosurgery ◽  
2019 ◽  
Vol 85 (2) ◽  
pp. E294-E303 ◽  
Author(s):  
Josue M Avecillas-Chasin ◽  
Fernando Alonso-Frech ◽  
Cristina Nombela ◽  
Clara Villanueva ◽  
Juan A Barcia

Abstract BACKGROUND Although deep brain stimulation (DBS) of the dorsolateral subthalamic nucleus (STN) is a well-established surgical treatment for patients with Parkinson disease (PD), there is still controversy about the relationship between the functional segregation of the STN and clinical outcomes. OBJECTIVE To correlate motor and neuropsychological (NPS) outcomes with the overlap between the volume of activated tissue (VAT) and the tractography-defined regions within the STN. METHODS Retrospective study evaluating 13 patients with PD treated with STN-DBS. With the aid of tractography, the STN was segmented into 4 regions: smaSTN (supplementary motor area STN), m1STN (primary motor area STN), mSTN (the sum of the m1STN and the smaSTN segments), and nmSTN (non-motor STN). We computed the overlap coefficients between these STN regions and the patient-specific VAT. The VAT outside of the STN was also calculated. These coefficients were then correlated with motor (Unified Parkinson's Disease Rating Scale, UPDRS III) and NPS outcomes. RESULTS Stimulation of the mSTN segment was significantly correlated with UPDRS III and bradykinesia improvement. Stimulation of the smaSTN segment, but not the m1STN one, had a positive correlation with bradykinesia improvement. Stimulation of the nmSTN segment was negatively correlated with the improvement in rigidity. Stimulation outside of the STN was correlated with some beneficial NPS effects. CONCLUSION Stimulation of the tractography-defined motor STN, mainly the smaSTN segment, is positively correlated with motor outcomes, whereas stimulation of the nmSTN is correlated with poor motor outcomes. Further validation of these results might help individualize and optimize targets prior to STN-DBS.


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