scholarly journals 87. Cerebrospinal Fluid Enzyme Studies in Experimental Brain Edema

1962 ◽  
Vol 4 (0) ◽  
pp. 207b-208
Author(s):  
S. AWAZU ◽  
M. EBARA ◽  
K. AKASHI ◽  
Y. KUSHIDA ◽  
S. MORIMOTO
Keyword(s):  
Cerebrospinal Fluid ◽  
Brain Edema ◽  
Experimental Brain Edema

Resolution of brain edema in severe brain injury at controlled high and low intracranial pressures

1984 ◽  
Vol 61 (4) ◽  
pp. 707-712 ◽  
Author(s):  
Meihong Cao ◽  
He Lisheng ◽  
Sun Shouzheng
Keyword(s):  
Cerebrospinal Fluid ◽  
Brain Injury ◽  
Brain Edema ◽  
External Ventricular Drainage ◽  
Blue Dye ◽  
Severe Brain Injury ◽  
Content Type ◽  
Intracranial Pressures ◽  
Low Levels ◽  
Cerebrospinal Fluid Protein

✓ A series of 87 patients with severe brain injury were studied. Intracranial pressure (ICP) monitoring and external ventricular drainage were used to control ICP at high and low levels. Clearance of ytterbium-169-labeled diethylenetriaminepentaacetic acid (169Yb-DTPA), Evans blue dye, and ventricular cerebrospinal fluid protein was measured at the two ICP levels over consecutive periods of 4 hours to confirm clearance of brain edema. The results support the hypothesis that brain edema is in part absorbed in the cerebrospinal fluid via transventricular flow.

The effects of glucosteroids on experimental cold-induced brain edema.

1971 ◽  
Vol 34 (4) ◽  
pp. 477-487 ◽  
Author(s):  
Robert E. Maxwell ◽  
Don M. Long ◽  
Lyle A. French
Keyword(s):  
Vascular Permeability ◽  
Brain Edema ◽  
Gray Matter ◽  
Dry Weight ◽  
Content Type ◽  
Beneficial Effects ◽  
Primary Reduction ◽  
Wet Weight ◽  
Experimental Brain Edema ◽  
Fine Print

✓ Although the beneficial effects of glucosteroids on brain edema are well documented and generally accepted clinically, investigations into their effects on experimental brain edema have been somewhat contradictory. In this study brain edema was produced by local cortical freezing in animals pretreated with glucosteroids and in untreated animals. Gross estimation of edema, wet weight-dry weight determination, and mechanical planimetry of areas of extravasated dye indicated a statistically significant reduction in edema of both white and gray matter at 24, 48, and 72 hours. Gross estimation of edema indicated a persisting effect with resolution of edema at 5 days in treated animals and from 7 to 12 days in untreated animals. These studies substantiate initial investigations and indicate a primary reduction in brain edema by glucosteroids. At least one of the effects of the glucosteroids appears to be reduction of the abnormal vascular permeability causing brain edema.

Acute dimethyl sulfoxide therapy in experimental brain edema

Neurosurgery ◽  
1981 ◽  
Vol 9 (1) ◽  
pp. 28???33 ◽  
Author(s):  
P E Camp ◽  
H E James ◽  
R Werner
Keyword(s):  
Dimethyl Sulfoxide ◽  
Brain Edema ◽  
Experimental Brain Edema

Acute dimethyl sulfoxide therapy in experimental brain edema

Neurosurgery ◽  
1982 ◽  
Vol 10 (3) ◽  
pp. 355???9 ◽  
Author(s):  
J Tsuruda ◽  
H E James ◽  
P E Camp ◽  
R Werner
Keyword(s):  
Dimethyl Sulfoxide ◽  
Brain Edema ◽  
Experimental Brain Edema

EFFECT OF MANNITOL ON CEREBROSPINAL FLUID DYNAMICS AND BRAIN EDEMA

1992 ◽  
Vol 77 (Supplement) ◽  
pp. A782 ◽  
Author(s):  
Y. Shapira ◽  
A. Artru ◽  
T. Donato ◽  
K. Powers ◽  
A. Lam
Keyword(s):  
Fluid Dynamics ◽  
Cerebrospinal Fluid ◽  
Brain Edema ◽  
Cerebrospinal Fluid Dynamics

Composition of isolated edema fluid in cold-induced brain edema

1979 ◽  
Vol 51 (1) ◽  
pp. 70-77 ◽  
Author(s):  
Jurjen Gazendam ◽  
K. Gwan Go ◽  
Annie K. van Zanten
Keyword(s):  
Cerebrospinal Fluid ◽  
White Matter ◽  
Brain Edema ◽  
Vasogenic Edema ◽  
Colloid Osmotic Pressure ◽  
Freezing Damage ◽  
Content Type ◽  
Edema Fluid ◽  
The Brain ◽  
Fine Print

✓ Edema fluid isolated from cats with cold-induced brain edema was subjected to analysis of electrolyte content, enzyme activities, colloid osmotic pressure and the radioactivity of intravenously injected 99mTc-labeled albumin. The findings corroborate the essential features of vasogenic edema, such as its origin from the blood plasma, its rapid propagation into the white matter of the brain as contrasted with the delayed spread into gray matter, and its contribution to composition of cerebrospinal fluid. Moreover, the elevated activities of cellular enzymes and K+ content of edema fluid point to the admixture with cellular contents due to the freezing damage.

scholarly journals 62. Experimental Brain Edema using Intensed Ultrasoud, especially on Effects of Urea, 20% Mannitol, Adreno-cortico-Steroids and Chimotripsin

1965 ◽  
Vol 7 ◽  
pp. 197a-197a
Author(s):  
Hirotoshi NONAKA ◽  
Kazufumi ITO ◽  
Shigeru ISHIKAWA ◽  
Kunio YUKISHITA
Keyword(s):  
Brain Edema ◽  
Experimental Brain Edema
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