scholarly journals Osteomas of the Skull: Comparison of Magnetic Resonance Imaging and Histological Findings

1995 ◽  
Vol 35 (1) ◽  
pp. 13-16
Author(s):  
Yasushi SHIBATA ◽  
Akira MATSUMURA ◽  
Yoshihiko YOSHII ◽  
Tadao NOSE
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Histological Findings ◽  
Resonance Imaging

scholarly journals Effect of Cerebrospinal Fluid Shunting on Experimental Syringomyelia: Magnetic Resonance Imaging and Histological Findings

1999 ◽  
Vol 39 (9) ◽  
pp. 668-676 ◽  
Author(s):  
Ayumi TAKAHASHI ◽  
Norihiko TAMAKI ◽  
Hiromitsu KURATA ◽  
Tatsuya NAGASHIMA ◽  
Etsuko FUJIMOTO
Keyword(s):  
Magnetic Resonance Imaging ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Histological Findings ◽  
Resonance Imaging ◽  
Cerebrospinal Fluid Shunting

Determining the Signal Source in Magnetic Resonance Imaging of Myelofibrotic Bone Marrow

Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 3140-3140
Author(s):  
Shinobu Matsuura ◽  
Shenia Patterson ◽  
Hector Lucero ◽  
Aaron Grant ◽  
Victoria L. M. Herrera ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Mouse Model ◽  
Conflicts Of Interest ◽  
Integrative Approach ◽  
Histological Findings ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Lipid Signal

Abstract Magnetic resonance imaging (MRI) is a promising diagnostic method for evaluation of bone marrow myelofibrosis for offering non-invasive, wider-area coverage over conventional histology. Although the most striking feature in histology of myelofibrotic bone marrow is the proliferation of reticulin fibers, the spectrum of findings involves abnormalities in cell number and composition, vessel proliferation, as well as possible pre-fibrotic abnormalities in matrix such as inflammation/edema. Correlation of MRI observations with such histological findings to accurately define the pathogenic phases of myelofibrosis has been challenging. Here, we present the first MRI analysis of myelofibrosis in a mouse model (Gata-1low mice) in an attempt to correlate MRI signal observations with histological findings. T2-weighted MRI images of femur bone marrow of Gata-1low animals at different ages (12 to 46 weeks) showed high MR signal intensity, absent in age-matched wild-type controls, that is detected as early as 12 weeks of age, before onset of histologically-defined fibrosis in this mouse model. MRI acquisitions employing fat suppression, a technique that suppresses signals from lipids, together with the absence of chemical shift artifacts in the images, excluded the possibility of lipids as the source of the prominent MR signal. To determine the source of this prominent non-lipid signal in Gata-1low bone marrow, cellular composition, vascularization and vascular permeability were tested. Our findings demonstrate a multi-source nature of MRI signals in bone marrow, which evolves from young (12 weeks) to old (40 weeks) Gata-1low bone marrow consistent with the pathologic progression of myelofibrosis. Data support the importance of an integrative approach to further the development of this non-invasive modality for following the dynamics and progression of this multifactorial pathology in humans. Disclosures No relevant conflicts of interest to declare.

scholarly journals Magnetic resonance imaging findings compared with histological findings of the labrum in hip osteoarthritis

2015 ◽  
Vol 44 (6) ◽  
pp. 767-775 ◽  
Author(s):  
Shiho Kanezaki ◽  
Asako Yamamoto ◽  
Shigeru Nakamura ◽  
Marie Osawa ◽  
Takashi Matsushita
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Hip Osteoarthritis ◽  
Imaging Findings ◽  
Histological Findings ◽  
Resonance Imaging
Sign in / Sign up

Export Citation Format

Share Document