Hyperdynamic Therapy for Cerebral Vasospasm

1990 ◽  
Vol 30 (5) ◽  
pp. 317-323 ◽  
Author(s):  
Hiromu HADEISHI ◽  
Makoto MIZUNO ◽  
Akifumi SUZUKI ◽  
Nobuyuki YASUI
Keyword(s):  
Cerebral Vasospasm ◽  
Hyperdynamic Therapy

scholarly journals Persistent Autoregulatory Disturbance after Angioplasty for Cerebral Vasospasm

2002 ◽  
Vol 8 (4) ◽  
pp. 409-415 ◽  
Author(s):  
D.K. Song ◽  
M.R. Harrigan ◽  
J.P. Deveikis ◽  
J.E. McGillicuddy
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Systolic Blood Pressure ◽  
Cerebral Vasospasm ◽  
Artery Aneurysm ◽  
Response To Therapy ◽  
Large Artery ◽  
Xenon Ct ◽  
Symptomatic Vasospasm ◽  
Hyperdynamic Therapy

Hyperdynamic therapy, consisting of hypervolemia, haemodilution, and hypertension, is an established treatment for cerebral vasospasm following subarachnoid haemorrhage. Angioplasty has emerged as an additional, effective treatment for symptomatic vasospasm. Loss of autoregulation, however, can occur despite effective angioplasty, underscoring the need for treatment with hyperdynamic therapy in combination with angioplasty. A 43-year-old woman underwent endovascular coiling of a ruptured left posterior communicating artery aneurysm. The patient went on to develop symptomatic vasospasm and was treated with hyperdynamic therapy and angioplasty. Autoregulation was assessed with xenon CT cerebral blood flow (CBF) measurement. An initial CBF study was obtained when the patient received dopamine and dobutamine infusions to maintain systolic blood pressure at 160 mmHg. The vasopressor drips were then temporarily held for twenty minutes, allowing the patient's systolic blood pressure to drop to 140 mmHg, and a repeat CBF study was obtained. Several days after angioplasty, CBF decreased significantly when the patient was taken off vasopressors, indicating impaired autoregulation. Hyperdynamic therapy was continued, and another CBF study one week later showed a return of autoregulation and normalization of CBF without induced hypertension. Autoregulation is disturbed during vasospasm. Although angioplasty can improve large artery blood flow during vasospasm, hyperdynamic therapy is also needed to maintain cerebral perfusion, particularly in the face of impaired autoregulation. Quantitative CBF measurement permits the maintenance of optimal CBF and monitoring of response to therapy.

scholarly journals The Effects of Hyperdynamic Therapy Using Dobutamine on Cerebral Circulation in Patients with Cerebral Vasospasm

1991 ◽  
Vol 19 (2) ◽  
pp. 203-209
Author(s):  
Hiromu HADEISHI ◽  
Nobuyuki YASUI ◽  
Akifumi SUZUKI ◽  
Makoto MIZUNO
Keyword(s):  
Cerebral Vasospasm ◽  
Cerebral Circulation ◽  
Hyperdynamic Therapy

Rapid Evolution and Rupture of an Incidental Aneurysm During Hyperdynamic Therapy for Cerebral Vasospasm

2021 ◽  
Vol 145 ◽  
pp. 205-209
Author(s):  
Gustavo Chagoya ◽  
Arsalaan Salehani ◽  
B. Ethan Tabibian ◽  
Nicholas M.B. Laskay ◽  
Brandon M. Fox ◽  
...  
Keyword(s):  
Cerebral Vasospasm ◽  
Rapid Evolution ◽  
Hyperdynamic Therapy

scholarly journals Effect of hyperdynamic therapy by albumin infusion on patients with neurological deficits associated with cerebral vasospasm

Nosotchu ◽  
1982 ◽  
Vol 4 (1) ◽  
pp. 44-53 ◽  
Author(s):  
Takeshi Saito ◽  
Takamaru Tanabe ◽  
Seiji Morii ◽  
Hiroshi Takagi ◽  
Kenzoh Yada
Keyword(s):  
Cerebral Vasospasm ◽  
Neurological Deficits ◽  
Albumin Infusion ◽  
Hyperdynamic Therapy

scholarly journals Hyperdynamic Therapy for Cerebral Vasospasm

2004 ◽  
Vol 13 (9) ◽  
pp. 636-645
Author(s):  
Hiromu Hadeishi ◽  
Akifumi Suzuki ◽  
Nobuyuki Yasui
Keyword(s):  
Cerebral Vasospasm ◽  
Hyperdynamic Therapy

scholarly journals Effects of albumin-hyperdynamic therapy on the cerebral vasospasm and hemodynamic parameters in the canine two-hemorrhage model

1990 ◽  
Vol 52 ◽  
pp. 80
Author(s):  
Hiroshi Shinyama ◽  
Toshiaki Akira ◽  
Masahiro Watanabe ◽  
Toru Matsui ◽  
Takao Asano
Keyword(s):  
Cerebral Vasospasm ◽  
Hemodynamic Parameters ◽  
Hyperdynamic Therapy
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