scholarly journals Diffuse Axonal Injury manifested as Corpus Callosum Damage on Magnetic Resonance Imaging

1989 ◽  
Vol 29 (6) ◽  
pp. 525-527
Author(s):  
Hiroshi TOMITA ◽  
Norihiko TAMAKI ◽  
Naoya TAKEDA ◽  
Shizuo OI ◽  
Satoshi MATSUMOTO
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Corpus Callosum ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Resonance Imaging

scholarly journals Role of magnetic resonance imaging in prediction of outcome in traumatic diffuse axonal injury: A single-centre observational study

2021 ◽  
Vol 18 (3) ◽  
pp. 39-43
Author(s):  
Suraj Thulung ◽  
Nikunj Yogi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Observational Study ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Resonance Imaging ◽  
Unfavourable Outcome ◽  
Neurological Assessment ◽  
Mri Findings

Introduction: Incidence of diffuse axonal injury has been estimated at 40-50% of hospitalizations. Recently, much interest has been directed towards the potential of newer imaging sequences of magnetic resonance imaging to investigate diffuse axonal injury (DAI) and to prognosticate the outcome. In this study, we correlated the magnetic resonance imaging grades of diffuse axonal injury with clinical outcome in terms of Glasgow Outcome Scale (GOS). Methods and Materials: A hospital based observational study was carried out at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences, Kathmandu in 69 patients of diffuse axonal injury between November 2017 to November 2018. Data was collected on patient and trauma characteristics, as well as neurological assessment and MRI findings. Outcome was assessed as favourable and unfavourable GOS for various MRI grades of diffuse axonal injury. Results: There were 21.74%, 42.03% and 36.23% of cases with grade I, II and III diffuse axonal injury respectively. There were 0 (0%), 2 (11.8%) and 15 (88.2%) cases of MRI grade I, II and III diffuse axonal injury in favourable GOS group and 15 (28.8%), 27 (51.9%) and 10 (19.2%) cases of MRI grade I, II and III diffuse axonal injury in unfavourable GOS group (p=0.00). Conclusion: This study showed that there was a significantly higher chance of unfavourable outcome with increasing MRI grades of diffuse axonal injury.

Role of Magnetic Resonance Imaging in Unconscious Patients due to Diffuse Axonal Injury and Its Prognostic Value

2017 ◽  
Vol 14 (01) ◽  
pp. 015-020
Author(s):  
Devendra Purohit ◽  
Virendra Sinha ◽  
Y. Karthikeyan
Keyword(s):  
Magnetic Resonance Imaging ◽  
Basal Ganglia ◽  
Magnetic Resonance ◽  
Prognostic Value ◽  
Axonal Injury ◽  
Diffuse Axonal Injury ◽  
Resonance Imaging ◽  
Gradient Recall Echo ◽  
The Mean ◽  
Unconscious Patients

Aim To study the long-term prognostic value of early magnetic resonance imaging (MRI) in unconscious patients with traumatic brain injury with findings of NCCT of the brain suggestive of diffuse axonal injury (DAI). Background Studies addressing the correlation of MRI with the pattern and duration of loss of consciousness due to DAI are few. The utility of MRI in predicting the functional outcome has not been reported in the Indian population. Materials and Methods In patients with DAI, MRI sequences including T1, T2*GRE (gradient recall echo), fluid-attenuated inversion recovery (FLAIR), diffusion-weighted imaging (DWI), and susceptibility-weighted imaging (SWI) were obtained. Glasgow coma scale (GCS) and Glasgow outcome scale (GOS) scores were documented at admission, on discharge, and at 3 months. Results A total of 54 patients (53 males, 1 female) were included in the study. The mean age was 27 ± 11.7 years. The mean GCS score on admission and at follow-up were 9.14 ± 2.3 and 11.7 ± 2.3, respectively. The mean GOS score on discharge and at 3 months were 2.6 ± 0.8 and 3.18 ± 1.02, respectively. SWI sequence detected maximum number of lesions followed by GRE and DWI. Patients with lesions in brainstem and basal ganglia were found to have a less favorable outcome as assessed by GCS and GOS at 3 months. There was no correlation between the total lesion load and outcome at 3 months. Conclusion In patients with DAI, SWI was found to be the most sensitive MRI sequence detecting maximum number of lesions. Patients with lesions in the brainstem and basal ganglia appear to have longer duration of unconsciousness and poorer outcome at 3 months.

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