scholarly journals K-5. Electron Microscopic Study of the ATPase Activity in the Human Brain Tumors

1971 ◽  
Vol 11 ◽  
pp. 328-328
Author(s):  
Mitsusuke MIYAGAMI ◽  
Saburo NAKAMURA ◽  
Nobuo MORIYASU
1962 ◽  
Vol 19 (9) ◽  
pp. 731-753 ◽  
Author(s):  
Anthony J. Raimondi ◽  
Sean Mullan ◽  
Joseph P. Evans

1973 ◽  
Vol 38 (4) ◽  
pp. 420-427 ◽  
Author(s):  
Saburo Nakamura ◽  
Mitsusuke Miyagami ◽  
Nobuo Moriyasu

✓ Ultrastructural localization of ATPase was demonstrated in 15 human brain tumors; ATPase activity in the tumor cell was outside the cell membrane and appeared in varying degrees according to the type of tumor. Nonglial tumors such as meningiomas and chromophobe pituitary adenomas showed more intense enzyme activity than gliomas; malignant tumors such as medulloblastoma and glioblastoma multiforme showed low activity. Blood vessels in the tumor showed poor ATPase activity in both endothelium and basement membrane; the lack of ATPase in the vascular wall may contribute to the breakdown of the blood-brain barrier.


1962 ◽  
Vol 15 (3) ◽  
pp. 451-462 ◽  
Author(s):  
Alex B. Novikoff ◽  
Guy de Thé ◽  
D. Beard ◽  
J. W. Beard

Thymus glands of chicks with leukemia induced by BAI strain A (myeloblastosis) virus were fixed in cold 4 per cent formaldehyde-sucrose. Frozen sections were incubated in the ATPase medium of Wachstein and Meisel and studied by light microscopy and electron microscopy. The ATPase activity of the virus is localized to the outermost membrane of the virus. The membrane of the blast-like cells of the thymus cortex from which the virus emerges, by budding, also possesses such activity. It appears likely that the outermost membrane of the virus is derived from the plasma membrane of these cells.


1975 ◽  
Vol 31 (3) ◽  
pp. 229-242 ◽  
Author(s):  
Jean-Jacques Hauw ◽  
Brigitte Berger ◽  
Raymond Escourolle

1970 ◽  
Vol 34 (1) ◽  
pp. 13-19 ◽  
Author(s):  
SEITOKU MIZUNO ◽  
SHIGERU TAKAMATSU ◽  
YUICHI TAMADA ◽  
KOHEI ARAYA ◽  
AKIHIKO TAKAHASHI ◽  
...  

2000 ◽  
Vol 68 (6) ◽  
pp. 3275-3279 ◽  
Author(s):  
Lars Greiffenberg ◽  
Werner Goebel ◽  
Kwang Sik Kim ◽  
Justin Daniels ◽  
Michael Kuhn

ABSTRACT Internalization of Listeria monocytogenes into human brain microvascular endothelial cells (HBMEC) has recently been demonstrated to be dependent upon the inlB gene. In the present scanning electron microscopic study we show that L. monocytogenes efficiently interacts with the surface of HBMEC in an inlB-independent manner which is also different from invasion. The inlB-dependent invasion of HBMEC by L. monocytogenes is accompanied by intracellular multiplication, movement, and production of bacterium-containing protrusions. These protrusions extend from the cell surface without perturbation of any adjacent cellular membrane.


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