An Overview of Peptide and Protein Absorption

2021 ◽  
Author(s):  
Toshiro Matsui
Keyword(s):  
Protein Absorption

Open-air synthesis of oligo(ethylene glycol)-functionalized polypeptides from non-purified N-carboxyanhydrides

2021 ◽  
Author(s):  
Zhengzhong Tan ◽  
Ziyuan Song ◽  
Tianrui Xue ◽  
Lining Zheng ◽  
Lei Jiang ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Protein Absorption ◽  
New Class

With PEG-like properties, such as hydrophilicity and stealth effect against protein absorption, oligo(ethylene glycol) (OEG)-functionalized polypeptides have emerged as a new class of biomaterials alternative to PEG with polypeptide-like properties....

(B) Mechanisms of peptide and protein absorption

1991 ◽  
Vol 7 (3) ◽  
pp. 365-385 ◽  
Author(s):  
Philip S. Burton ◽  
Robert A. Conradi ◽  
Allen R. Hilgers
Keyword(s):  
Protein Absorption

Clathrin‐dependent endocytosis predominantly mediates protein absorption by fat body from the hemolymph in Bombyx mori

2019 ◽  
Vol 27 (4) ◽  
pp. 675-686
Author(s):  
Yu‐Jie Wang ◽  
Shu‐Yan Li ◽  
Jia‐Ye Zhao ◽  
Kang Li ◽  
Jing Xu ◽  
...  
Keyword(s):  
Bombyx Mori ◽  
Fat Body ◽  
Protein Absorption

Tilapia protein hydrolyzate improves growth performance, protein absorption and antioxidant status in Silver catfish ( Rhamdia quelen )

2019 ◽  
Vol 50 (11) ◽  
pp. 3192-3201 ◽  
Author(s):  
Juliano Uczay ◽  
Eduardo Kelm Battisti ◽  
Rafael Lazzari ◽  
Marcos Luiz Pessatti ◽  
Thamara Luiza Schneider ◽  
...  
Keyword(s):  
Growth Performance ◽  
Antioxidant Status ◽  
Protein Absorption ◽  
Protein Hydrolyzate ◽  
Silver Catfish ◽  
Rhamdia Quelen

scholarly journals PROTEIN ABSORPTION BY RENAL CELLS

1973 ◽  
Vol 59 (1) ◽  
pp. 213-222 ◽  
Author(s):  
Samuel James Davidson
Keyword(s):  
Renal Cells ◽  
Protein Absorption

scholarly journals Impact of habituated dietary protein intake on fasting and postprandial whole-body protein turnover and splanchnic amino acid metabolism in elderly men: a randomized, controlled, crossover trial

2020 ◽  
Vol 112 (6) ◽  
pp. 1468-1484 ◽  
Author(s):  
Grith Højfeldt ◽  
Jacob Bülow ◽  
Jakob Agergaard ◽  
Ali Asmar ◽  
Peter Schjerling ◽  
...  
Keyword(s):  
Amino Acid ◽  
Protein Turnover ◽  
Protein Intake ◽  
Amino Acid Metabolism ◽  
Acid Metabolism ◽  
High Protein ◽  
Whole Body ◽  
Body Protein ◽  
Protein Absorption ◽  
Fasted State

ABSTRACT Background Efficacy of protein absorption and subsequent amino acid utilization may be reduced in the elderly. Higher protein intakes have been suggested to counteract this. Objectives We aimed to elucidate how habituated amounts of protein intake affect the fasted state of, and the stimulatory effect of a protein-rich meal on, protein absorption, whole-body protein turnover, and splanchnic amino acid metabolism. Methods Twelve men (65–70 y) were included in a double-blinded crossover intervention study, consisting of a 20-d habituation period to a protein intake at the RDA or a high amount [1.1 g · kg lean body mass (LBM)−1 · d−1 or >2.1 g · kg LBM−1 · d−1, respectively], each followed by an experimental trial with a primed, constant infusion of D8-phenylalanine and D2-tyrosine. Arterial and hepatic venous blood samples were obtained after an overnight fast and repeatedly 4 h after a standardized meal including intrinsically labeled whey protein concentrate and calcium-caseinate proteins. Blood was analyzed for amino acid concentrations and phenylalanine and tyrosine tracer enrichments from which whole-body and splanchnic amino acid and protein kinetics were calculated. Results High (compared with the recommended amount of) protein intake resulted in a higher fasting whole-body protein turnover with a resultant mean ± SEM 0.03 ± 0.01 μmol · kg LBM−1 · min−1 lower net balance (P < 0.05), which was not rescued by the intake of a protein-dense meal. The mean ± SEM plasma protein fractional synthesis rate was 0.13 ± 0.06%/h lower (P < 0.05) after habituation to high protein. Furthermore, higher fasting and postprandial amino acid removal were observed after habituation to high protein, yielding higher urea excretion and increased phenylalanine oxidation rates (P < 0.01). Conclusions Three weeks of habituation to high protein intake (>2.1 g protein · kg LBM−1 · d−1) led to a significantly higher net protein loss in the fasted state. This was not compensated for in the 4-h postprandial period after intake of a meal high in protein. This trial was registered at clinicaltrials.gov as NCT02587156.

Surface roughness influences the protein corona formation of glycosylated nanoparticles and alter their cellular uptake

Nanoscale ◽  
2019 ◽  
Vol 11 (48) ◽  
pp. 23259-23267 ◽  
Author(s):  
Alberto Piloni ◽  
Chin Ken Wong ◽  
Fan Chen ◽  
Megan Lord ◽  
Andreas Walther ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Cellular Uptake ◽  
Protein Corona ◽  
Biological Behavior ◽  
Protein Absorption ◽  
Corona Formation

Patterned nanoparticle surfaces can repel protein absorption and prevent the formation of a protein corona, which alters the biological behavior and therefore the fate of the nanoparticle.

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