Improving Workflow of the Ambient Ionization Mass Spectrometry Lipid Analysis by Utilizing a Pulse Ionizing Gas Enabled Direct Analysis in Real Time (DART) Source

2021 ◽  
Author(s):  
Brian Musselman ◽  
Frederick Li ◽  
Scott Campbell
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Lipid Analysis ◽  
Direct Analysis ◽  
Ambient Ionization ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Ambient Ionization Mass Spectrometry ◽  
Ionizing Gas

scholarly journals Characterizing the Dyes of Pre-Columbian Andean Textiles: Comparison of Ambient Ionization Mass Spectrometry and HPLC-DAD

Heritage ◽  
2021 ◽  
Vol 4 (3) ◽  
pp. 1639-1660
Author(s):  
Jennifer Campos Ayala ◽  
Samantha Mahan ◽  
Brenan Wilson ◽  
Kay Antúnez de Mayolo ◽  
Kathryn Jakes ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
High Performance ◽  
Direct Analysis ◽  
Ambient Ionization ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
South American ◽  
Flight Mass Spectrometry ◽  
Ambient Ionization Mass Spectrometry

The complex and colorful textiles of ancient Peru have long been a focus of technical study, particularly to characterize the sources of the wide variety of dyes utilized by these Andean artisans. This manuscript describes the characterization of the dyes of both primary (red, blue, and yellow) and secondary (purple, orange, and green) colors sampled from textiles spanning five major civilizations: the Paracas Necropolis, the Nazca, the Wari, the Chancay, and the Lambayeque, all from Peru. All but the Paracas Necropolis samples were part of technical conservation studies of the ancient South American textiles collections of the Michael C. Carlos Museum. Analysis of the dyes was carried out utilizing direct analysis in real time time-of-flight mass spectrometry (DART-MS) and paper spray MS. To validate these ambient ionization MS methods, the samples were further investigated using high-performance liquid chromatography (HPLC) with ultraviolet-visible diode array detection (DAD). These results show that ambient ionization MS methods are simple and fast for characterization of the general classes of dyes, e.g., plant reds vs. insect reds, and indigoids in blues and greens. Due to the myriad possible sources of yellow dyes and their tendency to undergo oxidative decomposition, positively identifying those components in these yarns was difficult, though some marker compounds and flavonoid decomposition products were readily identified by ambient ionization mass spectrometry.

More than just heat: ambient ionization mass spectrometry for determination of the species of origin of processed commercial products—application to psychoactive pepper supplements

2016 ◽  
Vol 8 (7) ◽  
pp. 1646-1658 ◽  
Author(s):  
Ashton D. Lesiak ◽  
Rabi A. Musah
Keyword(s):  
Mass Spectrometry ◽  
Statistical Analysis ◽  
Real Time ◽  
Plant Species ◽  
Direct Analysis ◽  
Ambient Ionization ◽  
Ionization Mass ◽  
Commercial Products ◽  
Ambient Ionization Mass Spectrometry

Direct analysis in real time mass spectrometry coupled with statistical analysis tools were applied to deduce the plant species from which a variety of commercial products were derived.

Mechanisms of Real-Time, Proximal Sample Processing during Ambient Ionization Mass Spectrometry

2013 ◽  
Vol 86 (1) ◽  
pp. 233-249 ◽  
Author(s):  
Andre R. Venter ◽  
Kevin A. Douglass ◽  
Jacob T. Shelley ◽  
Gregg Hasman ◽  
Elahe Honarvar
Keyword(s):  
Mass Spectrometry ◽  
Real Time ◽  
Ambient Ionization ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Sample Processing ◽  
Ambient Ionization Mass Spectrometry

scholarly journals Review of Recent Advances in Lipid Analysis of Biological Samples via Ambient Ionization Mass Spectrometry

Metabolites ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 781
Author(s):  
Haiyan Lu ◽  
Hua Zhang ◽  
Shuling Xu ◽  
Lingjun Li
Keyword(s):  
Mass Spectrometry ◽  
Biological Samples ◽  
Lipid Analysis ◽  
Sample Pretreatment ◽  
Ambient Ionization ◽  
Structural Elucidation ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Ambient Ionization Mass Spectrometry

The rapid and direct structural characterization of lipids proves to be critical for studying the functional roles of lipids in many biological processes. Among numerous analytical techniques, ambient ionization mass spectrometry (AIMS) allows for a direct molecular characterization of lipids from various complex biological samples with no/minimal sample pretreatment. Over the recent years, researchers have expanded the applications of the AIMS techniques to lipid structural elucidation via a combination with a series of derivatization strategies (e.g., the Paternò–Büchi (PB) reaction, ozone-induced dissociation (OzID), and epoxidation reaction), including carbon–carbon double bond (C=C) locations and sn-positions isomers. Herein, this review summarizes the reaction mechanisms of various derivatization strategies for C=C bond analysis, typical instrumental setup, and applications of AIMS in the structural elucidation of lipids from various biological samples (e.g., tissues, cells, and biofluids). In addition, future directions of AIMS for lipid structural elucidation are discussed.

Ambient ionization mass spectrometry: real-time, proximal sample processing and ionization

2017 ◽  
Vol 9 (34) ◽  
pp. 4896-4907 ◽  
Author(s):  
R. Javanshad ◽  
A. R. Venter
Keyword(s):  
Mass Spectrometry ◽  
Sample Preparation ◽  
Real Time ◽  
Ambient Ionization ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Sample Analysis ◽  
Sample Processing ◽  
Ambient Ionization Mass Spectrometry

A review of ambient ionization mass spectrometry highlighting the central role of sample preparation immediate to and during sample analysis.

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