scholarly journals Monitoring of arsenic in groundwater of adjoining areas of Gorakhpur District (U.P.), India.

2018 ◽  
Vol 7 (4) ◽  
pp. 2205
Author(s):  
Vira Tripathi ◽  
Anil K. Dwivedi
Keyword(s):  
High Risk ◽  
Arsenic Contamination ◽  
Asian Countries ◽  
Major Health Problem ◽  
Major Health ◽  
Risk Zone ◽  
Arsenic In Groundwater ◽  
Groundwater Arsenic ◽  
Risk Areas ◽  
Study Sites

Arsenic contamination is an enormous worldwide problem. Groundwater arsenic contamination and sufferings of people have been reported in 20 countries in different parts of the world. The magnitude is considered highest in 5 Asian countries and the severity is in order of Bangladesh> India> Mangolia > China> Taiwan. The contamination of drinking water supplies with natural Occurring arsenic is major health problem. The paper deals estimation of arsenic in groundwater of Gorakhpur district. For this purpose, total 36 study sites were selected in urban as well as in rural area of the district, further the samples were collected from shallow bore well as from the deep bore wells. It was concluded that 5 areas are under high risk zone of arsenic, 5 areas are at the low risk and 26 areas which are monitored are in the safe zone of arsenic. High risk areas are crossing the permissible level of arsenic consumption according to WHO.

scholarly journals Obesity in achondroplasia patients: from evidence to medical monitoring

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Celine Saint-Laurent ◽  
Laura Garde-Etayo ◽  
Elvire Gouze
Keyword(s):  
High Risk ◽  
Genetic Disease ◽  
Patient Management ◽  
Bone Growth ◽  
Medical Monitoring ◽  
Metabolic Complications ◽  
Major Health Problem ◽  
Major Health ◽  
Short Limb ◽  
Growth Abnormalities

AbstractAchondroplasia is a rare genetic disease representing the most common form of short-limb dwarfism. It is characterized by bone growth abnormalities that are well characterized and by a strong predisposition to abdominal obesity for which causes are unknown. Despite having aroused interest at the end of the 20 h century, there are still only very little data available on this aspect of the pathology. Today, interest is rising again, and some studies are now proposing mechanistic hypotheses and guidance for patient management. These data confirm that obesity is a major health problem in achondroplasia necessitating an early yet complex clinical management. Anticipatory care should be directed at identifying children who are at high risk to develop obesity and intervening to prevent the metabolic complications in adults. In this review, we are regrouping available data characterizing obesity in achondroplasia and we are identifying the current tools used to monitor obesity in these patients.

Potential for arsenic contamination of rice in Bangladesh: spatial analysis and mapping of high risk areas

2006 ◽  
Vol 6 (4/5/6) ◽  
pp. 298 ◽  
Author(s):  
Zev Ross ◽  
John M. Duxbury ◽  
Stephen D. DeGloria ◽  
Debi Narayan Rudra Paul
Keyword(s):  
Spatial Analysis ◽  
High Risk ◽  
Arsenic Contamination ◽  
Risk Areas

scholarly journals Fire hazard zonation of Bardia National Park, Nepal: A disaster preparedness approach

2014 ◽  
Vol 2 ◽  
pp. 27-33
Author(s):  
B. Ghimire ◽  
K. Bhujel ◽  
K. Rijal
Keyword(s):  
High Risk ◽  
National Park ◽  
Fire Hazard ◽  
Fire Risk ◽  
Hazard Zonation ◽  
Validation Process ◽  
Risk Zone ◽  
Active Fire ◽  
Risk Areas ◽  
Park Area

This study was focused to prepare fire hazard map of Bardia National Park (BNP) through fire hazard zonation model. BNP is located at western Terai (lowland plains) of Nepal. The model was prepared by using four sub-models. The sub-models were prepared by considering nine parameters selected on the basis of their significance in fire risk assessments and their data availability. Remotely sensed data and Geographic Information System (GIS) were used during model preparation and validation process. The output map from the model was validated using Moderate Resolution Imaging Spectroradiometer (MODIS) active fire points (2001- May 2014) within BNP. Very high fire risk areas were identified along southern boundary; Northeast and Northwest part of the park covering about 5% of the park area. Similarly, about 31% of the park area was identified as high risk zone and 31.43% area of BNP was identified as medium risk zone. MODIS active fire data was very useful for validation process that showed proportionate result with the area coverage of predicted risk classes. The validation result suggests that this prepared model can be used to prepare fire hazard zonation maps and preparedness plans of areas similar to BNP. The plans to prevent and control wildfire in BNP should be focused on high risk areas through preparedness initiatives, awareness activities and capacity building of fire fighting team. Reducing surface fuel load and fuel continuity during pre-fire season (Dec-Feb) in general and particularly during February shall reduce fire occurrences and its damage to a great extent.

Detection of Mycobacterium tuberculosis in smear negative sputum by PCR

2012 ◽  
Vol 6 (2) ◽  
pp. 2-6 ◽  
Author(s):  
Mohammad Jobayer ◽  
SM Shamsuzzaman ◽  
Kazi Zulfiquer Mamun
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Accurate Method ◽  
Major Health Problem ◽  
Major Health ◽  
Tuberculosis Patients ◽  
Diagnostic Potential ◽  
Total Death ◽  
Smear Negative ◽  
Negative Sputum

Pulmonary tuberculosis is a major health problem in Bangladesh that is responsible for about 7% of total death in a year. This study was conducted to isolate and identify Mycobacterium tuberculosis from sputum and to evaluate the efficacy of PCR as a modern diagnostic tool, for diagnosis of pulmonary tuberculosis, especially in the smear negative cases. One hundred and fifty suspected pulmonary TB patients (male/ female: 97/53) were included in this study. Single morning sputum was collected from each patient and diagnostic potential of PCR was compared with staining and culture. Twenty five (16.7%) sputum were positive by ZN stained smear. Among 125 smear negative samples, 13 (10.4%) yielded growth in culture in LJ media and 21 (16.8%) samples were positive by PCR. The sensitivity and specificity of PCR in smear negative cases was 100% and 92.9% respectively. Mean detection time in PCR was 24 hours. PCR detected M. tuberculosis in 21 smear negative and 9 culture negative samples. For diagnosis of tuberculosis in smear negative cases, PCR directly from sputum was a very sensitive and accurate method. In conclusion, PCR may be done, especially in clinically suspected pulmonary tuberculosis patients who remain negative by conventional methods.DOI: http://dx.doi.org/10.3329/bjmm.v6i2.19368 Bangladesh J Med Microbiol 2012; 06(02): 2-6

Prevention and Treatment of Early Childhood Caries (ECC)

2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Jeffrey .
Keyword(s):  
Early Childhood ◽  
Health Problem ◽  
Early Childhood Caries ◽  
Health Providers ◽  
Missing Teeth ◽  
Optimal Basis ◽  
Major Health Problem ◽  
Major Health ◽  
Childhood Caries

Early Childhood Caries (ECC) is a chronic disease that can be prevented. It commonlyaffects children involving in one or more decayed (with lesions or not) teeth, missing teeth (dueto caries), or teeth with fillings in children aged under 71 months. The disease is sometimesoverlooked, but this condition usually affects the general health of children. Early detection ofEarly Childhood Caries (ECC) can prevent problems which are harmful to children. Therefore,the ECC must be prevented and for teeth that have had dental caries they should be givenproper treatment so as not to worsen and affect the quality of life in children. Prevention of thisdisease is a significant component in any health program to prepare for the optimal basis forthe oral health of children. This condition will become a serious health problem if not handledproperly, and it is a major health problem for health providers throughout the world.Primarypreventive must be initiated since a woman getting pregnant.Keywords: Early Childhood Caries (ECC), prevention, treatment

Salivary and Serum Biochemical Alterations in Patients with Acute Viral Hepatitis

2018 ◽  
Vol 69 (3) ◽  
pp. 747-751 ◽  
Author(s):  
Daniela Gabriela Badita ◽  
Iulia Ioana Stanescu ◽  
Andra Balcangiu Stroescu ◽  
Dan Piperea Sianu ◽  
Daniela Miricescu ◽  
...  
Keyword(s):  
Viral Hepatitis ◽  
Hepatitis A ◽  
Hepatitis A Virus ◽  
World Population ◽  
Major Health Problem ◽  
Major Health ◽  
Biochemical Alterations ◽  
B Virus ◽  
Serum Biochemical ◽  
Viral Hepatitis A

Viral hepatitis represents a major health problem worldwide. Approximately 1.4 million people are infected with hepatitis A virus every year, although given that most of the cases evolve asymptomatically the real number could be even higher. At the same time, hepatitis B virus affects up to 30% of the world population and represents one of the main causes of cirrhosis and hepatocellular carcinoma. Thus, it is very important to understand the physiopathology of viral hepatitis A and B not only for the diagnosis, but also for the therapeutic protocol. The present research aimed to determine if HAV and HBV can alter serum and salivary levels of total protein and of 2 important electrolytes: calcium and potassium.

Imaging of Bacteria: Is there Any Hope for the Future Based on Past Experience?

2018 ◽  
Vol 24 (7) ◽  
pp. 772-786 ◽  
Author(s):  
Thomas Ebenhan ◽  
Elena Lazzeri ◽  
Olivier Gheysens
Keyword(s):  
Clinical Practice ◽  
Sterile Inflammation ◽  
Ageing Population ◽  
Major Health Problem ◽  
Major Health ◽  
Number Of Patients ◽  
Implanted Medical Devices ◽  
Neutropenic Patients ◽  
Socio Economic Impact ◽  
Made In

Infectious diseases remain a major health problem and cause of death worldwide. It is expected that the socio-economic impact will further intensify due to escalating resistance to antibiotics, an ageing population and an increase in the number of patients under immunosuppressive therapy and implanted medical devices. Even though radiolabeled probes and leukocytes are routinely used in clinical practice, it might still be difficult to distinguish sterile inflammation from inflammation caused by bacteria. Moreover, the majority of these probes are based on the attraction of leukocytes which may be hampered in neutropenic patients. Novel approaches that can be implemented in clinical practice and allow for swift diagnosis of infection by targeting the microorganism directly, are posing an attractive strategy. Here we review the current strategies to directly image bacteria using radionuclides and we provide an overview of the preclinical efforts to develop and validate new approaches. Indeed, significant progress has been made in the past years, but very few radiopharmaceuticals (that were promising in preclinical studies) have made it into clinical practice. We will discuss the challenges that remain to select good candidates for imaging agents targeting bacteria.

Wogonin Alleviates Hyperglycemia Through Increased Glucose Entry into Cells Via AKT/GLUT4 Pathway

2019 ◽  
Vol 25 (23) ◽  
pp. 2602-2606 ◽  
Author(s):  
Shahzad Khan ◽  
Mohammad A. Kamal
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Modern World ◽  
Major Health Problem ◽  
Major Health ◽  
Chronic Hyperglycemia ◽  
Main Factor

: Insulin resistance and type 2 Diabetes mellitus resulting in chronic hyperglycemia is a major health problem in the modern world. Many drugs have been tested to control hyperglycemia which is believed to be the main factor behind many of the diabetes-related late-term complications. Wogonin is a famous herbal medicine which has been shown to be effective in controlling diabetes and its complications. In our previous work, we showed that wogonin is beneficial in many ways in controlling diabetic cardiomyopathy. In this review, we mainly explained wogonin anti-hyperglycemic property through AKT/GLUT4 pathway. Here we briefly discussed that wogonin increases Glut4 trafficking to plasma membrane which allows increased entry of glucose and thus alleviates hyperglycemia. Conclusion: Wogonin can be used as an anti-diabetic and anti-hyperglycemic drug and works via AKT/GLUT4 pathway.

Management of Prameha with Mustadi Kwatha - A Case Study

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Dr. Akshay H. Malshikare ◽  
Dr. Sharada Chikurte
Keyword(s):  
Type Ii Diabetes ◽  
Single Case ◽  
Type Ii Diabetes Mellitus ◽  
Ayurvedic Medicine ◽  
Type Ii ◽  
Single Case Study ◽  
Major Health Problem ◽  
Major Health ◽  
Uncontrolled Diabetes

Diabetes is a major health problem in whole world. In spite of many drugs available, uncontrolled diabetes remains a challenge. Moreover, some anti-diabetic drugs are on the verge of withdrawal due to its adverse effects. So, there is an acute need for a new effective and safe drug. So in this case study we used Ayurvedic medicine ‘Mustadi Kwatha’ mentioned in Bhaishajya Ratnawali in Prameha Chikitsa. A single case study was done on use of Mustadi Kwatha on Type II Diabetes Mellitus. Significant reduction was seen in blood sugar level fasting and post-prandial.

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