A Quantitative Structure-Activity Relationship Study on Some Na+ and K+ Channel Blockers: Role of Molecular Connectivity Index

S. Gupta; Anitha Paleti; S. Mekapati; A. Nagappa; S. Kumaran

doi:10.2174/1570180054038422

A Quantitative Structure-Activity Relationship Study on Some Na+ and K+ Channel Blockers: Role of Molecular Connectivity Index

Letters in Drug Design & Discovery ◽

10.2174/1570180054038422 ◽

2005 ◽

Vol 2 (4) ◽

pp. 287-290 ◽

Cited By ~ 1

Author(s):

S. Gupta ◽

Anitha Paleti ◽

S. Mekapati ◽

A. Nagappa ◽

S. Kumaran

Keyword(s):

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

K Channel ◽

Channel Blockers ◽

Quantitative Structure ◽

Molecular Connectivity ◽

Molecular Connectivity Index ◽

Structure Activity ◽

Relationship Study

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Synthesis and Quantitative Structure-Activity Relationship of Dequalinium Analogs as K+ Channel Blockers: Investigations on the Role of the Substituent at Position 4 of the Quinoline Ring

Journal of Medicinal Chemistry ◽

10.1021/jm00018a013 ◽

1995 ◽

Vol 38 (18) ◽

pp. 3536-3546 ◽

Cited By ~ 16

Author(s):

Dimitrios Galanakis ◽

Julie A. D. Calder ◽

C. Robin Ganellin ◽

Clive S. Owen ◽

Philip M. Dunn

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

K Channel ◽

Channel Blockers ◽

Quinoline Ring ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of

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A quantitative structure–activity relationship study on some HIV-1 protease inhibitors using molecular connectivity index

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(01)00210-3 ◽

2001 ◽

Vol 9 (11) ◽

pp. 3059-3063 ◽

Cited By ~ 26

Author(s):

P. Gayathri ◽

V. Pande ◽

R. Sivakumar ◽

S.P. Gupta

Keyword(s):

Protease Inhibitors ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Molecular Connectivity ◽

Molecular Connectivity Index ◽

Structure Activity ◽

Relationship Study ◽

Hiv 1

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Molecular Connectivity in Quantitative Structure-Activity Relationship Study of Anesthetic and Toxic Activity of Aliphatic Hydrocarbons, Ethers, and Ketones

Journal of Pharmaceutical Sciences ◽

10.1002/jps.2600670437 ◽

1978 ◽

Vol 67 (4) ◽

pp. 566-568 ◽

Cited By ~ 35

Author(s):

Thérèse Di Paolo

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Aliphatic Hydrocarbons ◽

Activity Relationship ◽

Quantitative Structure ◽

Molecular Connectivity ◽

Toxic Activity ◽

Structure Activity ◽

Relationship Study

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Synthesis and Quantitative Structure−Activity Relationship of a Novel Series of Small Conductance Ca2+-Activated K+Channel Blockers Related to Dequalinium

Journal of Medicinal Chemistry ◽

10.1021/jm950520i ◽

1996 ◽

Vol 39 (2) ◽

pp. 359-370 ◽

Cited By ~ 19

Author(s):

Dimitrios Galanakis ◽

Carole A. Davis ◽

C. Robin Ganellin ◽

Philip M. Dunn

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

K Channel ◽

Channel Blockers ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of ◽

Small Conductance

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A Quantitative Structure-Activity Relationship Study on Some Series of Potassium Channel Blockers

Medicinal Chemistry ◽

10.2174/157340609787049244 ◽

2009 ◽

Vol 5 (1) ◽

pp. 87-92 ◽

Cited By ~ 4

Author(s):

V. Kumar Satuluri ◽

Jyostna Seelam ◽

S. Gupta

Keyword(s):

Potassium Channel ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Channel Blockers ◽

Quantitative Structure ◽

Structure Activity ◽

Potassium Channel Blockers ◽

Relationship Study

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Support Vector Machine-Based Quantitative Structure-Activity Relationship Study of Cholesteryl Ester Transfer Protein Inhibitors

Chemical Biology & Drug Design ◽

10.1111/j.1747-0285.2009.00800.x ◽

2009 ◽

Vol 73 (5) ◽

pp. 558-571 ◽

Cited By ~ 12

Author(s):

Siavash Riahi ◽

Eslam Pourbasheer ◽

Mohammad Reza Ganjali ◽

Parviz Norouzi

Keyword(s):

Support Vector Machine ◽

Cholesteryl Ester ◽

Cholesteryl Ester Transfer Protein ◽

Quantitative Structure Activity Relationship ◽

Activity Relationship ◽

Support Vector ◽

Quantitative Structure ◽

Transfer Protein ◽

Structure Activity ◽

Relationship Study

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Outliers in SAR and QSAR: 3. Importance of considering the role of water molecules in protein–ligand interactions and quantitative structure–activity relationship studies

Journal of Computer-Aided Molecular Design ◽

10.1007/s10822-021-00377-7 ◽

2021 ◽

Author(s):

Ki Hwan Kim

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Water Molecules ◽

Quantitative Structure ◽

Protein Ligand Interactions ◽

Structure Activity ◽

Ligand Interactions

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Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo(1,4)oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.45.1975 ◽

1997 ◽

Vol 45 (12) ◽

pp. 1975-1983 ◽

Cited By ~ 3

Author(s):

Takeshi YAMAMOTO ◽

Manabu HORI ◽

Ikuo WATANABE ◽

Hisayoshi TSUTSUI ◽

Kengo HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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A quantitative structure-activity relationship study on a series of 10 para-substituted toluenes binding to cytochrome P4502B4 (CYP2B4), and their hydroxylation rates

Biochemical Pharmacology ◽

10.1016/0006-2952(95)00188-6 ◽

1995 ◽

Vol 50 (5) ◽

pp. 619-625 ◽

Cited By ~ 24

Author(s):

David F.V. Lewis ◽

Costas Ioannides ◽

Dennis V. Parke

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Substituted Toluenes ◽

Relationship Study

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Acute toxicity of substituted biphenyls todaphnia magnaand quantitative structure‐activity relationship study

Toxicological and Environmental Chemistry ◽

10.1080/02772249909358661 ◽

1999 ◽

Vol 68 (3-4) ◽

pp. 267-273

Author(s):

C. M. Zhu ◽

L. R. Kong ◽

H. Hong ◽

Q. G. Huang ◽

L. S. Wang

Keyword(s):

Acute Toxicity ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Study

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