Substrates, Inducers, Inhibitors and Structure-Activity Relationships of Human Cytochrome P450 2C9 and Implications in Drug Development

2009 ◽  
Vol 16 (27) ◽  
pp. 3480-3675 ◽  
Author(s):  
S.-F. Zhou ◽  
Z.-W. Zhou ◽  
L.-P. Yang ◽  
J.-P. Cai
Keyword(s):  
Cytochrome P450 ◽  
Drug Development ◽  
Cytochrome P450 2C9 ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Human Cytochrome

Amino Acid Residues Affecting the Activities of Human Cytochrome P450 2C9 and 2C19

2002 ◽  
Vol 30 (8) ◽  
pp. 931-936 ◽  
Author(s):  
Toshiro Niwa ◽  
Akira Kageyama ◽  
Kae Kishimoto ◽  
Yoshiyasu Yabusaki ◽  
Fumihide Ishibashi ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Amino Acid ◽  
Amino Acid Residues ◽  
Cytochrome P450 2C9 ◽  
Human Cytochrome

Effects of Pomegranate Juice on Human Cytochrome P450 2C9 and Tolbutamide Pharmacokinetics in Rats

2006 ◽  
Vol 35 (2) ◽  
pp. 302-305 ◽  
Author(s):  
Masashi Nagata ◽  
Muneaki Hidaka ◽  
Hiroshi Sekiya ◽  
Yohei Kawano ◽  
Keishi Yamasaki ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Pomegranate Juice ◽  
Cytochrome P450 2C9 ◽  
Human Cytochrome ◽  
Pharmacokinetics In Rats

Catalytic activities of human cytochrome P450 2C9*1, 2C9*3 and 2C9*13

Xenobiotica ◽  
2005 ◽  
Vol 35 (9) ◽  
pp. 853-861 ◽  
Author(s):  
Y. Guo ◽  
Y. Wang ◽  
D. Si ◽  
P. J. Fawcett ◽  
D. Zhong ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Cytochrome P450 2C9 ◽  
Catalytic Activities ◽  
Human Cytochrome
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