scholarly journals Biological detection and tagging using tailorable, reactive, highly fluorescent chemosensors.

2006 ◽  
Author(s):  
Timothy J Shepodd ◽  
Thomas Zifer ◽  
James Ross McElhanon ◽  
Larry A Rahn
Keyword(s):  
Fluorescent Chemosensors ◽  
Biological Detection

Importance of Bodipy-based Chemosensors for Cations and Anions in Bioimaging Applications

2020 ◽  
Vol 17 ◽  
Author(s):  
Ahmed Nuri Kursunlu ◽  
Elif Bastug ◽  
Ersin Guler
Keyword(s):  
Photophysical Properties ◽  
Direct Determination ◽  
Spectroscopic Properties ◽  
Selective Detection ◽  
Fluorescent Chemosensors ◽  
Design Strategies ◽  
Online Activity ◽  
Fluorescence Studies ◽  
Bio Imaging ◽  
Living Organisms

Background: Chemosensor compounds are useful for sensitive selective detection of cations and anions with fluorophore groups in an attempt to develop the effective selectivity of the sensors. Although familiar fluorescent sensors utilizing inter-molecular interactions with the cations and anions, an extraordinary endeavor was executed the preparation of fluorescent-based sensor compounds. 4,4-difluoro-4- bora-3a,4a-diaza-s-indacene (Bodipy) and its derivatives were firstly used as an agent in the imaging of biomolecules due to their interesting structures, complexation, and fluorogenic properties. Among the fluorescent chemosensors used for cations and anions, Bodipy-based probes stand out owing to the excellent properties such as sharp emission profile, high stability, etc. In this review, we emphasize the Bodipy-based chemosensor compounds, which have been used to image cations and anions in living cells, because of as well as the biocompatibility and spectroscopic properties. Methods: Research and online content related to chemosensor online activity is reviewed. The advances, sensing mechanisms and design strategies of the fluorophore exploiting selective detection of some cation and anions with Bodipy-based chemosensors are explained. It could be claimed that the using of Bodipy-based chemosensors is very important for cations and anions in bio-imaging applications. Results: Molecular sensors or chemosensors are molecules that show a change can be detected when affected by the analyte. They are capable of producing a measurable signal when they are selective for a particular molecule. Molecular and ion recognition that it is important in biological systems such as enzymes, genes, environment, and chemical fields. Due to the toxic properties of many heavy metal ions, it is of great importance to identify these metals due to their harmful effects on living metabolism and the pollution they create in the environment. This process can be performed with analytical methods based on atomic absorption and emission. The fluorescence methods among chemosensor systems have many advantages such as sensitivity, selectivity, low price, simplicity of using the instrument and direct determination in solutions. The fluorescence studies can be applied at nanomolar concentrations. Conclusion: During a few decades, a lot of Bodipy-based chemosensors for the detection of cations & anions have been investigated in bio-imaging applications. For the Bodipy-based fluorescent chemosensors, the Bodipy derivatives were prepared by different ligand groups for the illumination of the photophysical and photochemical properties. The synthesized Bodipy-based chemosensors have remarkable photophysical properties, such as a high quantum yield, strong molar absorption coefficient etc. Moreover, these chemosensors were successfully implemented on living organisms for the detection of analytes.

Various Sensing Mechanisms for the Design of Naphthalimide based Chemosensors Emerging in Recent Years

2020 ◽  
Vol 13 (4) ◽  
pp. 262-289
Author(s):  
Duraisamy Udhayakumari
Keyword(s):  
Metal Ions ◽  
Intramolecular Charge Transfer ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Intramolecular Proton Transfer ◽  
Biological Applications ◽  
Fluorescent Chemosensors ◽  
The Past ◽  
Photo Induced Electron Transfer ◽  
Displacement Approach

In the design of novel fluorescent chemosensors, investigation of new sensing mechanisms between recognition and signal reporting units is of increasing interest. In recent years, a smart chemosensor probe containing a 1,8-naphthalimide moiety could be developed as a fluorescent and colorimetric sensor for toxic anions, metal ions, biomolecules, nitroaromatics, and acids and be further applied to monitor the relevant biological applications. In this field, several problems and challenges still exist. This critical review is mainly focused on various sensing mechanisms that have emerged in the past few years, such as Photo-Induced Electron Transfer (PET), Intramolecular Charge Transfer (ICT), Fluorescence Resonance Energy Transfer (FRET), Excited-State Intramolecular Proton Transfer (ESIPT), hydrogen bonding and displacement approach. The review concludes with some current and future perspectives, including the use of the naphthalimides for sensing anions, metal ions, biomolecules, nitroaromatics and acids and their potential uses in various fields.

Hybrid nanoparticle based fluorescence switch for recognition of ketoprofen in aqueous media

2020 ◽  
Vol 5 (8) ◽  
pp. 1428-1436
Author(s):  
Anu Saini ◽  
Manpreet Kaur ◽  
Mayank ◽  
Anil Kuwar ◽  
Navneet Kaur ◽  
...  
Keyword(s):  
Aqueous Media ◽  
Fluorescent Chemosensors ◽  
Fluorescence Switch ◽  
Nanomolar Detection ◽  
Hybrid Nanoparticle

Hybrid nanoassembly, fluorescent chemosensors, selective response to ketoprofen, and nanomolar detection.

Resonant acoustic profiling for biological detection and diagnostics

2008 ◽  
Author(s):  
W. Chiu ◽  
C.J. Hammond ◽  
R. Hammond ◽  
L. Harding ◽  
E. Hawkins ◽  
...  
Keyword(s):  
Biological Detection ◽  
Acoustic Profiling

Biological detection and analysis of mercury toxicity to alfalfa (Medicago sativa) plants

Chemosphere ◽  
2008 ◽  
Vol 70 (8) ◽  
pp. 1500-1509 ◽  
Author(s):  
Zhao Sheng Zhou ◽  
Shao Jing Wang ◽  
Zhi Min Yang
Keyword(s):  
Medicago Sativa ◽  
Mercury Toxicity ◽  
Biological Detection

scholarly journals Characterization of Airborne Bacteria at an Underground Subway Station

2012 ◽  
Vol 78 (6) ◽  
pp. 1917-1929 ◽  
Author(s):  
Marius Dybwad ◽  
Per Einar Granum ◽  
Per Bruheim ◽  
Janet Martha Blatny
Keyword(s):  
Real Life ◽  
Performance Criteria ◽  
Anthropogenic Sources ◽  
Subway Station ◽  
Airborne Bacteria ◽  
Surveillance Systems ◽  
Operational Environment ◽  
Biological Detection ◽  
Content Type ◽  
Subway Stations

ABSTRACTThe reliable detection of airborne biological threat agents depends on several factors, including the performance criteria of the detector and its operational environment. One step in improving the detector's performance is to increase our knowledge of the biological aerosol background in potential operational environments. Subway stations are enclosed public environments, which may be regarded as potential targets for incidents involving biological threat agents. In this study, the airborne bacterial community at a subway station in Norway was characterized (concentration level, diversity, and virulence- and survival-associated properties). In addition, a SASS 3100 high-volume air sampler and a matrix-assisted laser desorption ionization–time of flight mass spectrometry-based isolate screening procedure was used for these studies. The daytime level of airborne bacteria at the station was higher than the nighttime and outdoor levels, and the relative bacterial spore number was higher in outdoor air than at the station. The bacterial content, particle concentration, and size distribution were stable within each environment throughout the study (May to September 2010). The majority of the airborne bacteria belonged to the generaBacillus,Micrococcus, andStaphylococcus, but a total of 37 different genera were identified in the air. These results suggest that anthropogenic sources are major contributors to airborne bacteria at subway stations and that such airborne communities could harbor virulence- and survival-associated properties of potential relevance for biological detection and surveillance, as well as for public health. Our findings also contribute to the development of realistic testing and evaluation schemes for biological detection/surveillance systems by providing information that can be used to mimic real-life operational airborne environments in controlled aerosol test chambers.

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