scholarly journals Test Plan for Tank 241-AZ-101 Solubility Screening Tests

1999 ◽  
Author(s):  
J.C. PERSON
Keyword(s):  
Screening Tests ◽  
Test Plan

Experimental Activity on the Tubular SOFC CHP100 kWe Field Unit in Italy: Factor Significance, Effects and Regression Model Analysis

2006 ◽  
Author(s):  
M. Cali` ◽  
G. Orsello ◽  
M. Santarelli ◽  
P. Leone
Keyword(s):  
Regression Models ◽  
Thermal Power ◽  
Sensitivity Coefficient ◽  
Factorial Analysis ◽  
Screening Tests ◽  
Combined Effects ◽  
Test Plan ◽  
Utilization Factor ◽  
Independent Variables ◽  
Field Unit

The CHP 100 kWe tubular SOFC plant built by Siemens is operating at the Gas Turbine Technologies (GTT) in Turin. The generator started up on the June 2005 and produces electric and thermal power used in the factory. A first period of the activity was needed to lead the operation of the SOFC plant at the nominal condition and to reach the complete conditioning of the SOFC tubular fuel cells. Then, in order to characterize the operation of the generator and of the cogenerative system a first experimental campaign was designed by using the factorial analysis. With these methods, the effect of some independent variables (factors) on the plant operation is analyzed in form of screening tests: the analysis allows one to estimate the significance of the main and combined effects of each considered factor through an analysis of variance (ANOVA) on the experimental data. Moreover, the test plan has been designed by using a simple 2k factorial and a 2k factorial with spherical central composite design (CCD); these approaches allow to obtain respectively first-order and second-order regression models for some chosen dependent variables (i.e. DC and AC electric power, generator voltage, recovered heat etc...). The test plan has been performed at the fixed generator current of 500 Amps with two repetitions for each designed treatment. The factorial analysis has been applied considering two factors (22 factorial analysis): setup temperature of the generator and fuel utilization factor. First, the significance of the main and combined effects of the two considered factor has been evaluated. Then, the obtained data have been analyzed by using the Response Surface Methodology analysis (RSM). Finally, the regression models have been obtained for every dependent variable analyzed, with an outline of the sensitivity coefficient linking the dependent and the independent variables.

Early Development of Drug-Induced Hepatic Necrosis

1971 ◽  
Vol 29 ◽  
pp. 576-577
Author(s):  
F. G. Zaki ◽  
E. Detzi ◽  
C. H. Keysser
Keyword(s):  
Early Development ◽  
Hepatic Necrosis ◽  
Screening Tests ◽  
Dense Matrix ◽  
Sprague Dawley ◽  
Electron Microscopic ◽  
Drug Induced ◽  
Hepatocellular Damage ◽  
Sprague Dawley Rats ◽  
Microscopic Studies

This study represents the first in a series of investigations carried out to elucidate the mechanism(s) of early hepatocellular damage induced by drugs and other related compounds. During screening tests of CNS-active compounds in rats, it has been found that daily oral administration of one of these compounds at a dose level of 40 mg. per kg. of body weight induced diffuse massive hepatic necrosis within 7 weeks in Charles River Sprague Dawley rats of both sexes. Partial hepatectomy enhanced the development of this peculiar type of necrosis (3 weeks instead of 7) while treatment with phenobarbital prior to the administration of the drug delayed the appearance of necrosis but did not reduce its severity.Electron microscopic studies revealed that early development of this liver injury (2 days after the administration of the drug) appeared in the form of small dark osmiophilic vesicles located around the bile canaliculi of all hepatocytes (Fig. 1). These structures differed from the regular microbodies or the pericanalicular multivesicular bodies. They first appeared regularly rounded with electron dense matrix bound with a single membrane. After one week on the drug, these vesicles appeared vacuolated and resembled autophagosomes which soon developed whorls of concentric lamellae or cisterns characteristic of lysosomes (Fig. 2). These lysosomes were found, later on, scattered all over the hepatocytes.

Kognition und Motorik

2015 ◽  
Vol 72 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Stephanie A. Bridenbaugh
Keyword(s):  
Dual Task ◽  
Screening Tests ◽  
Kognitive Defizite ◽  
Ältere Erwachsene

Es gibt eine starke Assoziation zwischen Kognition und Mobilität. Ältere Erwachsene mit Gangdefiziten haben ein erhöhtes Risiko, kognitive Defizite, sogar eine Demenz, zu entwickeln. Kognitive Defizite wiederum sind mit einer Verschlechterung des Gehens assoziiert. Sowohl kognitive als auch Mobilitätsdefizite sind mit einem erhöhten Sturzrisiko verbunden. Untersuchungen der Kognition, vor allem der Exekutivfunktionen, und die funktionale Mobilität sollen daher ein wesentlicher Bestandteil jedes umfassenden geriatrischen Assessments sein. Einige schnelle Screening-Tests können in der Hausarztpraxis durchgeführt werden, um Mobilitätsprobleme zu erfassen. Falls diese pathologisch ausfallen, sollten genauere Ganguntersuchungen veranlasst werden. Bei Untersuchungen des Ganges sind Dual-Task Paradigmen (Gehen und gleichzeitig eine andere Aufgaben ausführen) besonders aussagekräftig in der Früherkennung von Mobilitäts- und auch Hirnleistungsdefiziten. Die Früherkennung erlaubt eine frühzeitige Implementierung von gezielten Interventionen, um die Gangsicherheit und möglicherweise auch gewisse Hirnleistungen zu verbessern.

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