scholarly journals Industrial applications study. Volume V. Bibliography of relevant literature. Final report

1976 ◽  
Author(s):  
Harry L. Brown ◽  
Bernard B. Hamel ◽  
Som Karamchetty ◽  
William H. Steigelmann ◽  
Birur C. Gajanana ◽  
...  
Keyword(s):  
Relevant Literature ◽  
Industrial Applications ◽  
Final Report

scholarly journals Industrial applications study. Volume III. Technology data base evaluation of waste recovery systems. Final report

1977 ◽  
Author(s):  
Harry L. Brown ◽  
Bernard B. Hamel ◽  
Som Karamchetty ◽  
William H. Steigelmann ◽  
Birur C. Gajanana ◽  
...  
Keyword(s):  
Data Base ◽  
Industrial Applications ◽  
Final Report ◽  
Waste Recovery

scholarly journals Development of CVD Diamond for Industrial Applications Final Report CRADA No. TC-2047-02

2017 ◽  
Author(s):  
M. Caplan ◽  
R. Olstad ◽  
H. Jory ◽  
A. L. Vikharov
Keyword(s):  
Cvd Diamond ◽  
Industrial Applications ◽  
Final Report

scholarly journals Industrial applications study. Volume IV. Industrial plant surveys. Final report. [Waste heat recovery and utilization]

1977 ◽  
Author(s):  
Harry L. Brown ◽  
Bernard B. Hamel ◽  
Som Karamchetty ◽  
William H. Steigelmann ◽  
Birur C. Gajanana ◽  
...  
Keyword(s):  
Heat Recovery ◽  
Waste Heat Recovery ◽  
Waste Heat ◽  
Industrial Applications ◽  
Industrial Plant ◽  
Final Report

scholarly journals DESIGN OF BEACH NOURISHMENT SCHEME

1986 ◽  
Vol 1 (20) ◽  
pp. 107
Author(s):  
K.W. Pilarczyk ◽  
J. Van Overeem ◽  
W.T. Bakker
Keyword(s):  
Relevant Literature ◽  
Beach Nourishment ◽  
Coastal Engineering ◽  
Beach Erosion ◽  
Public Works ◽  
Task Group ◽  
Maintenance Cost ◽  
Final Report ◽  
Coastal Morphology ◽  
Optimum Solution

An artificial beach nourishment used to replenish an eroding part of a coast may seem expensive and the need for repetition may discourage coastal managers. However, careful considerations of capital and maintenance cost frequently prove that it may be, in fact, the optimum solution. An added advantage is that the recreational function of the beach is preserved. In spite of a great number of research-reports and publications on coastal processes and beach nourishment, the practical applicability of this knowledge is still in an initial stage, i.e. formulating the general concepts and trying to test their validity and practical applicability. On the other hand, the solution of many practical coastal engineering problems cannot wait until complete understanding of these processes and the existing knowledge on this subject (though limited) should be made available for designers and managers involved in coastal engineering. This was the main reason for the Rijkswaterstaat (Dutch Public Works Department) to prepare a manual on artificial beach nourishment. In 1983, this Department established the task-group 'Profile Formation of Beaches', with the aim to study the relevant aspects of beach nourishment. These aspects concern among other things the influence of a beach fill on the coastal morphology and the environment, and the design and execution of a beach nourishment scheme. The members of the task-group originate from various governmental departments, research institutes (Delft Hydraulics) and private organisations (Volker Stevin Dredging, Zanen Verstoep Dredging Contractors). In addition to the members of the working-group some other persons and organizations (also outside the Netherlands) have contributed to the final report. The results of the studies have been described in a Manual on Beach Nourishment (Manual, 1986). This manual contains both theoretical and practical information, and is intended for persons and organisations who are involved in the prevention of beach erosion. Nearly all available and relevant literature to this subject has been incorporated. The actual paper reviews part of the contents of the Manual and summarizes aspects related to the aim, the different types and the design process of beach nourishment schemes.

scholarly journals Porous Inorganic and Hybrid Systems for Drug Delivery: Future Promise in Combatting Drug Resistance and Translation to Botanical Applications

2019 ◽  
Vol 26 (33) ◽  
pp. 6107-6131 ◽  
Author(s):  
Junling Guo ◽  
Bruno D. Mattos ◽  
Blaise L. Tardy ◽  
Vanessa M. Moody ◽  
Gao Xiao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Relevant Literature ◽  
Industrial Applications ◽  
Porous Particles ◽  
Metalorganic Framework ◽  
One Step ◽  
Delivery Vehicles ◽  
Therapeutic Properties ◽  
Organic Particles

Background: Porous micro- and nanoparticles have the capacity to encapsulate a large quantity of therapeutics, making them promising delivery vehicles for a variety of applications. This review aims to highlight the latest development of inorganic and hybrid (inorganic/ organic) particles for drug delivery with an additional emphasis on combatting drug resistant cancer. We go one step further and discuss delivery applications beyond medicinal delivery, as there is generally a translation from medicinal delivery to botanic delivery after a short lag time. Methods: We undertook a search of relevant peer-reviewed publications. The quality of the relevant papers was appraised using standard tools. The characteristics of the papers are described herein, and the relevant material and therapeutic properties are discussed. Results: We discuss 4 classes of porous particles in terms of drug delivery and theranostics. We specifically focus on silica, calcium carbonate, metal-phenolic network, and metalorganic framework particles. Other relevant biomedically relevant applications are discussed and we highlight outstanding therapeutic results in the relevant literature. Conclusion: The findings of this review confirm the importance of studying and utilizing porous particles for therapeutic delivery. Moreover, we show that the properties of porous particles that make them promising for medicinal drug delivery also make them promising candidates for agro-industrial applications.

Biomarker Tests for Molecularly Targeted Therapies: Laying the Foundation and Fulfilling the Dream

2016 ◽  
Vol 34 (17) ◽  
pp. 2061-2066 ◽  
Author(s):  
Gary H. Lyman ◽  
Harold L. Moses
Keyword(s):  
Patient Care ◽  
Clinical Outcomes ◽  
Targeted Therapies ◽  
Large Scale ◽  
Relevant Literature ◽  
Final Report ◽  
Cancer Therapies ◽  
Institute Of Medicine ◽  
Regulatory Oversight ◽  
Wide Range

Precision medicine focuses on the management of individual patients on the basis of biomarkers and other distinguishing characteristics, with the overarching objective of improving clinical outcomes. The rapid proliferation of biomarker tests and targeted therapies has revolutionized patient care in a variety of serious disorders. Targeted cancer therapies interrupt oncogenic molecular pathways driven by mutations, overexpression, or translocation of specific genes. However, there is concern that the emergence of large-scale genomic data is exceeding our capacity to appropriately analyze and interpret the results. In 2014, the Institute of Medicine convened the Committee on Policy Issues in the Clinical Development and Use of Biomarkers for Molecularly Targeted Therapies. This committee conducted a study to develop recommendations to address diverse and interconnected development, regulatory, clinical practice, and reimbursement issues. The committee conducted an extensive search of the relevant literature and invited testimony from a wide range of experts in the field. The final report of the committee’s study and deliberations was released on March 4, 2016, focusing on ways to achieve 10 goals to further advance the development and appropriate clinical use of biomarker tests for molecularly targeted therapies. This article presents an overview of the committee’s study and resulting recommendations, which cover establishment of clinical utility, regulatory oversight, coverage and reimbursement, health system data integration, as well as education and access. The committee’s recommendations presented and discussed here are fundamentally grounded in the understanding that, when properly validated and appropriately implemented, these assays and corresponding therapies hold considerable promise to enhance the quality of patient care and improve meaningful clinical outcomes.

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