scholarly journals Statistical analysis of longitudinal growth data on adolescents exposed in utero to the atomic bombs, Hiroshima and Nagasaki. Final report, January 1, 1971--February 29, 1972

1972 ◽  
Author(s):  
B.S. Pasternack
Keyword(s):  
Statistical Analysis ◽  
In Utero ◽  
Longitudinal Growth ◽  
Final Report ◽  
Growth Data

scholarly journals Pubertal growth in normal Thai children: a longitudinal study

2010 ◽  
Vol 4 (5) ◽  
pp. 793-795
Author(s):  
Suttipong Wacharasindhu ◽  
Vichit Supornsilchai ◽  
Suphab Aroonparkmongkol ◽  
Thaninee Sahakitrungrueng
Keyword(s):  
Longitudinal Study ◽  
Growth Parameters ◽  
Longitudinal Growth ◽  
Compensatory Mechanism ◽  
Growth Data ◽  
Clinical Practices ◽  
Normal Children ◽  
Pubertal Onset ◽  
Pubertal Growth ◽  
Height Gain

Abstract Background: Pubertal growth data in Thai children has been reported as cross-sectional studies. There is no longitudinal study in Thai children. Objective: Investigate the longitudinal growth data in normal Thai children including the relationship between age at pubertal onset and other growth parameters. Material and method: Eighty-eight normal children (44 boys, 44 girls) were longitudinally assessed for the growth and puberty until they reached their final adult height. Pubertal staging was assessed by the Tanner method. Results: Mean age of pubertal onset was 10.2 ± 1.2 years for girls and 12.2 ± 1.0 years for boys. Total pubertal height gain was 18.3 ± 4.0 cm for girls and 22.3 ± 4.4 cm for boys. Total pubertal height gain had a negative correlation with age at pubertal onset for girls, but not for boys. Conclusion: The onset of puberty was not much changed from previous studies. Girls with early puberty had a higher pubertal height gain. This might be due to a compensatory mechanism. These longitudinal growth data can be used as a reference in clinical practices for Thai children.

The impact of random-effect misspecification on percentile estimation for longitudinal growth data

2012 ◽  
Vol 31 (28) ◽  
pp. 3708-3718 ◽  
Author(s):  
Kyeongmi Cheon ◽  
Paul S. Albert ◽  
Zhiwei Zhang
Keyword(s):  
Random Effect ◽  
Longitudinal Growth ◽  
Growth Data ◽  
Percentile Estimation ◽  
The Impact

scholarly journals Multilevel growth curve models that incorporate a random coefficient model for the level 1 variance function

2017 ◽  
Vol 27 (11) ◽  
pp. 3478-3491 ◽  
Author(s):  
Harvey Goldstein ◽  
George Leckie ◽  
Christopher Charlton ◽  
Kate Tilling ◽  
William J Browne
Keyword(s):  
Random Effects ◽  
Repeated Measures ◽  
Random Effect ◽  
Growth Function ◽  
Individual Variability ◽  
Growth Patterns ◽  
Variance Function ◽  
Longitudinal Growth ◽  
Growth Data ◽  
The Mean

Aim To present a flexible model for repeated measures longitudinal growth data within individuals that allows trends over time to incorporate individual-specific random effects. These may reflect the timing of growth events and characterise within-individual variability which can be modelled as a function of age. Subjects and methods A Bayesian model is developed that includes random effects for the mean growth function, an individual age-alignment random effect and random effects for the within-individual variance function. This model is applied to data on boys’ heights from the Edinburgh longitudinal growth study and to repeated weight measurements of a sample of pregnant women in the Avon Longitudinal Study of Parents and Children cohort. Results The mean age at which the growth curves for individual boys are aligned is 11.4 years, corresponding to the mean ‘take off’ age for pubertal growth. The within-individual variance (standard deviation) is found to decrease from 0.24 cm2 (0.50 cm) at 9 years for the ‘average’ boy to 0.07 cm2 (0.25 cm) at 16 years. Change in weight during pregnancy can be characterised by regression splines with random effects that include a large woman-specific random effect for the within-individual variation, which is also correlated with overall weight and weight gain. Conclusions The proposed model provides a useful extension to existing approaches, allowing considerable flexibility in describing within- and between-individual differences in growth patterns.

London Archive of Longitudinal Growth Data

1986 ◽  
Vol 13 (2) ◽  
pp. 179-182
Author(s):  
J.M. Tanner ◽  
L.A. Cox
Keyword(s):  
Longitudinal Growth ◽  
Growth Data

scholarly journals Feeding Intolerance and Poor Growth in Infants with Gastroschisis: Longitudinal Experience with Consecutive Patients over Thirteen Years

2015 ◽  
Vol 4 (4) ◽  
pp. 42 ◽  
Author(s):  
Saloni Balgi ◽  
Sarita Singhal ◽  
Georgia Mueller ◽  
Beau Batton
Keyword(s):  
Weight Gain ◽  
Linear Regression ◽  
Hospital Length Of Stay ◽  
Longitudinal Growth ◽  
Feeding Intolerance ◽  
Growth Data ◽  
Term Infants ◽  
Poor Growth ◽  
Factors Associated ◽  
Hospital Factors

Objectives: 1) To investigate in-hospital factors associated with delayed tolerance of full volume enteral nutrition and 2) To assess longitudinal growth in a contemporary population of infants with gastroschisis.Design: Retrospective single-center study of all infants with gastroschisisSetting: Level III neonatal intensive care unit in a free-standing Children’s HospitalDuration: 13.5 yearsMaterials & Methods: Detailed data regarding demographics, nutritional support, growth, and infant outcomes was collected for all infants with gastroschisis. Linear regression was used to investigate in-hospital factors associated with feeding intolerance and poor growth.Results: For 52 infants, the median gestational age at birth was 36 weeks, the median postnatal age to achieve full feeds was 22 days, and median in-hospital weight gain was 18 gm/day. With linear regression, there was a positive association between time to full feeds and both hospital length of stay (adjusted R2=0.503, p<0.0001) and (unexpectedly) in-hospital weight gain (adjusted R2=0.125, p=0.0248). There was a negative association between in-hospital weight gain and preterm birth (adjusted R2=0.125, p=0.0356). For infants with longitudinal growth data, 35% had a weight <5th percentile (of whom 67% were preterm).Conclusions: Many infants with gastroschisis have poor growth before and after hospital discharge. Aggressive feeding advancement may be a contributing factor to this finding and preterm infants may be at greater risk for poor growth than term infants.

Effect of the T-mutation on histogenesis of the mouse embryo under the testis capsule

Development ◽  
1979 ◽  
Vol 50 (1) ◽  
pp. 21-30
Author(s):  
H. Fujimoto ◽  
K. O. Yanagisawa
Keyword(s):  
Statistical Analysis ◽  
Bone Formation ◽  
Mouse Embryo ◽  
In Utero ◽  
Mouse Embryos ◽  
Wild Type ◽  
Germ Layers ◽  
Derivatives Of

Mouse embryos homozygous for the T-mutation show abnormalities, severer at the posterior embryonic regions, by day 9 of gestation and die before day 11 in utero. To analyse developmental potentiality of the T/T embryos, fragments of their anterior and posterior portions were grafted into the testes of adult T/+ mice, and examined histologically for the tissues formed after 1 month. The grafted tissues of the T/T embryos grew beyond the destined lethal stage and gave rise to benign teratomas composed of mature tissues. Although there were some different features of the tissues formed in the teratomas derived from different portions and stages of the embryos, their types were essentially identical between wild-type and the mutant teratomas. Statistical analysis showed that frequency of the cartilage and/or bone formation was significantly lower in the posterior mutant teratomas. It cannot be concluded, however, that this difference is essentially caused by T-mutation. The main conclusion of present experiments is that grafted portions of T/T embryos have the potentiality to develop intoteratomas containing derivatives of all three germ layers.

Fourth (Final) Report on a Test of McDougall'S Lamarckian Experiment on the Training of Rats

1954 ◽  
Vol 31 (3) ◽  
pp. 307-321
Author(s):  
W. E. AGAR ◽  
F. H. DRUMMOND ◽  
O. W. TIEGS ◽  
M. M. GUNSON
Keyword(s):  
Statistical Analysis ◽  
Control Experiment ◽  
Learning Rate ◽  
Final Report ◽  
Long Duration ◽  
Laboratory Colony ◽  
Steady Improvement ◽  
Lamarckian Inheritance ◽  
Rate Of Learning

This is the final report of an experiment of 20 years' duration, in which we have repeated, in its essentials, the well-known experiment of William McDougall purporting to reveal a Lamarckian inheritance of the effects of training on rats. The test is one involving light discrimination, and McDougall recorded a steady improvement in the rate of learning on a succession of 32 generations; but he omitted to check the results against a properly conducted control. Our experiment confirms McDougall to the extent that we too have obtained long duration trends of improvement in learning-rate (Figs. 2, 3); but we find that the effect is not sustained, and that it is, moreover, shown also by a control experiment, using animals of untrained ancestry. This forbids a Lamarckian interpretation. Statistical analysis of the data indicates that the ‘condition’ of the rat markedly affects its speed of learning, and that progressive changes in learning-rate, over a succession of generations, are in reality correlated with the health of the laboratory colony, which is subject to periods of decline and recovery.

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