scholarly journals DNA sequencing with capillary electrophoresis and single cell analysis with mass spectrometry

1998 ◽  
Author(s):  
N. Fung
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Dna Sequencing ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis

Mass Spectrometry for Single-Cell Analysis

2020 ◽  
pp. 1-17
Author(s):  
Dinesh K. Patel ◽  
Sayan Deb Dutta ◽  
Ki-Taek Lim
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis

Single-cell analysis by ambient mass spectrometry

2017 ◽  
Vol 90 ◽  
pp. 14-26 ◽  
Author(s):  
Yunyun Yang ◽  
Yanying Huang ◽  
Junhui Wu ◽  
Ning Liu ◽  
Jiewei Deng ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Ambient Mass Spectrometry ◽  
Cell Analysis

Single Cell Analysis with Probe ESI-Mass Spectrometry: Detection of Metabolites at Cellular and Subcellular Levels

2014 ◽  
Vol 86 (8) ◽  
pp. 3809-3816 ◽  
Author(s):  
Xiaoyun Gong ◽  
Yaoyao Zhao ◽  
Shaoqing Cai ◽  
Shujie Fu ◽  
Chengdui Yang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis ◽  
Mass Spectrometry Detection ◽  
Esi Mass Spectrometry

scholarly journals Automated Capillary Electrophoresis System for Fast Single-Cell Analysis

2013 ◽  
Vol 85 (9) ◽  
pp. 4797-4804 ◽  
Author(s):  
Alexandra J. Dickinson ◽  
Paul M. Armistead ◽  
Nancy L. Allbritton
Keyword(s):  
Capillary Electrophoresis ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis ◽  
Capillary Electrophoresis System ◽  
Electrophoresis System

scholarly journals Recent Advances and New Perspectives in Capillary Electrophoresis-Mass Spectrometry for Single Cell “Omics”

Molecules ◽  
2018 ◽  
Vol 24 (1) ◽  
pp. 42 ◽  
Author(s):  
Kellen DeLaney ◽  
Christopher Sauer ◽  
Nhu Vu ◽  
Lingjun Li
Keyword(s):  
Mass Spectrometry ◽  
Capillary Electrophoresis ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Resolving Power ◽  
Ms Analysis ◽  
Large Populations ◽  
Analysis Workflow ◽  
High Level ◽  
Near Future

Accurate clinical therapeutics rely on understanding the metabolic responses of individual cells. However, the high level of heterogeneity between cells means that simply sampling from large populations of cells is not necessarily a reliable approximation of an individual cell’s response. As a result, there have been numerous developments in the field of single-cell analysis to address this lack of knowledge. Many of these developments have focused on the coupling of capillary electrophoresis (CE), a separation technique with low sample consumption and high resolving power, and mass spectrometry (MS), a sensitive detection method for interrogating all ions in a sample in a single analysis. In recent years, there have been many notable advancements at each step of the single-cell CE-MS analysis workflow, including sampling, manipulation, separation, and MS analysis. In each of these areas, the combined improvements in analytical instrumentation and achievements of numerous researchers have served to drive the field forward to new frontiers. Consequently, notable biological discoveries have been made possible by the implementation of these methods. Although there is still room in the field for numerous further advances, researchers have effectively minimized various limitations in detection of analytes, and it is expected that there will be many more developments in the near future.

scholarly journals Design of an automated capillary electrophoresis platform for single-cell analysis

2019 ◽  
pp. 191-221 ◽  
Author(s):  
David H. Abraham ◽  
Matthew M. Anttila ◽  
Luke A. Gallion ◽  
Brae V. Petersen ◽  
Angela Proctor ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Single Cell ◽  
Single Cell Analysis ◽  
Cell Analysis
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