Remediation plan for fluorescent light fixtures containing polychlorinated biphenyls (PCBs)

Abstract The goal of university training programs is to educate speech-language pathology and audiology students to become competent and independent practitioners, with the ability to provide high quality and professional services to the public. This article describes the behaviors of “at-risk” student clinicians, so they may be identified early in their practica and remediation may be implemented. The importance of establishing a student at-risk protocol is discussed as well as a remediation plan for these students. This article summarized the Auburn University Speech and Hearing Clinic’s Student At-Risk Protocol, which may serve as a model for university training programs. The challenges of implementing such a protocol are also discussed.

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Pesticide and non-dioxin-like polychlorinated biphenyls (NDL-PCBs) residues in foodstuffs from Ismailia city, Egypt

Food Additives & Contaminants ◽

10.1080/02652030701726618 ◽

2008 ◽

pp. 1-9 ◽

Cited By ~ 3

Author(s):

N. Loutfy ◽

M. Fuerhacker ◽

C. Lesueur ◽

M. Gartner ◽

M. Tawfic Ahmed ◽

...

Keyword(s):

Polychlorinated Biphenyls

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Serum Dioxins and Polychlorinated Biphenyls Are Associated With Growth Among Russian Boys

PEDIATRICS ◽

10.1542/peds.2009-3556d ◽

2010 ◽

Vol 127 (2) ◽

pp. peds.2009-3556d-peds.2009-3556d

Keyword(s):

Polychlorinated Biphenyls

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Fatty Liver and Impaired Hepatic Metabolism Alters the Congener-Specific Distribution of Polychlorinated Biphenyls (PCBs) in Mice with a Liver-Specific Deletion of Cytochrome P450 Reductase

10.26434/chemrxiv.12026904.v1 ◽

2020 ◽

Author(s):

Xueshu Li ◽

Chun-Yun Zhang ◽

Hans-Joachim Lehmler

Keyword(s):

Cytochrome P450 ◽

Polychlorinated Biphenyls ◽

Fatty Liver ◽

Partition Coefficients ◽

Hepatic Metabolism ◽

Gas Chromatography Mass Spectrometry ◽

Cytochrome P450 Reductase ◽

P450 Reductase ◽

Specific Distribution ◽

Specific Deletion

Polychlorinated biphenyls (PCBs) are persistent organic pollutants that are linked to adverse health outcomes. PCB tissue levels are determinants of PCB toxicity; however, it is unclear how factors, such as an altered metabolism and/or a fatty liver, affect PCB distribution in vivo. We determined the congener-specific disposition of PCBs in mice with a liver specific deletion of cytochrome P450 reductase (KO), a model of fatty liver with impaired hepatic metabolism, and wildtype (WT) mice. Male and female KO and WT mice were exposed orally to Aroclor 1254, a technical PCB mixture. PCBs were quantified in adipose, blood, brain and liver tissues by gas chromatography-mass spectrometry. PCB profiles and levels in tissues were genotype and sex dependent. PCB levels were higher in the liver from KO compared to WT mice. PCB profiles showed clear differences between tissues from the same exposure group. While experimental tissue : blood partition coefficients in KO and WT mice did not follow the trends predicted using a composition-based model, the agreement between experimental and calculated partition coefficients was still reasonable. Thus, a fatty liver and/or an impaired hepatic metabolism alter the distribution of PCBs in mice and the magnitude of the partitioning of PCBs from blood into tissues can be approximated using composition-based models.<br>

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