scholarly journals Kinetics of Materials at Extreme Conditions: Understanding the Time Dependent Approach to Equilibrium at MaRIE

2017 ◽  
Author(s):  
R. G. Kraus ◽  
D. Mcnabb ◽  
M. Kumar ◽  
J. Eggert ◽  
J. Borg ◽  
...  
Keyword(s):  
Time Dependent ◽  
Extreme Conditions ◽  
Approach To Equilibrium ◽  
Kinetics Of

scholarly journals In vivo analysis of the size- and time-dependent uptake of NaYF4:Yb,Er upconversion nanocrystals by pumpkin seedlings

2015 ◽  
Vol 3 (1) ◽  
pp. 144-150 ◽  
Author(s):  
J. Nordmann ◽  
S. Buczka ◽  
B. Voss ◽  
M. Haase ◽  
K. Mummenhoff
Keyword(s):  
Time Dependent ◽  
Upconversion Nanocrystals ◽  
In Vivo Analysis ◽  
Kinetics Of

We have investigated the kinetics of the uptake and the translocation of nanoparticles of different size in plants.

scholarly journals Determinants of mRNA stability in Dictyostelium discoideum amoebae: differences in poly(A) tail length, ribosome loading, and mRNA size cannot account for the heterogeneity of mRNA decay rates.

1988 ◽  
Vol 8 (5) ◽  
pp. 1957-1969 ◽  
Author(s):  
R A Shapiro ◽  
D Herrick ◽  
R E Manrow ◽  
D Blinder ◽  
A Jacobson
Keyword(s):  
Steady State ◽  
Dictyostelium Discoideum ◽  
Mrna Decay ◽  
Decay Rates ◽  
Time Dependent ◽  
Translational Efficiency ◽  
Cdna Clones ◽  
Dependent Manner ◽  
Significant Difference ◽  
Kinetics Of

As an approach to understanding the structures and mechanisms which determine mRNA decay rates, we have cloned and begun to characterize cDNAs which encode mRNAs representative of the stability extremes in the poly(A)+ RNA population of Dictyostelium discoideum amoebae. The cDNA clones were identified in a screening procedure which was based on the occurrence of poly(A) shortening during mRNA aging. mRNA half-lives were determined by hybridization of poly(A)+ RNA, isolated from cells labeled in a 32PO4 pulse-chase, to dots of excess cloned DNA. Individual mRNAs decayed with unique first-order decay rates ranging from 0.9 to 9.6 h, indicating that the complex decay kinetics of total poly(A)+ RNA in D. discoideum amoebae reflect the sum of the decay rates of individual mRNAs. Using specific probes derived from these cDNA clones, we have compared the sizes, extents of ribosome loading, and poly(A) tail lengths of stable, moderately stable, and unstable mRNAs. We found (i) no correlation between mRNA size and decay rate; (ii) no significant difference in the number of ribosomes per unit length of stable versus unstable mRNAs, and (iii) a general inverse relationship between mRNA decay rates and poly(A) tail lengths. Collectively, these observations indicate that mRNA decay in D. discoideum amoebae cannot be explained in terms of random nucleolytic events. The possibility that specific 3'-structural determinants can confer mRNA instability is suggested by a comparison of the labeling and turnover kinetics of different actin mRNAs. A correlation was observed between the steady-state percentage of a given mRNA found in polysomes and its degree of instability; i.e., unstable mRNAs were more efficiently recruited into polysomes than stable mRNAs. Since stable mRNAs are, on average, "older" than unstable mRNAs, this correlation may reflect a translational role for mRNA modifications that change in a time-dependent manner. Our previous studies have demonstrated both a time-dependent shortening and a possible translational role for the 3' poly(A) tracts of mRNA. We suggest, therefore, that the observed differences in the translational efficiency of stable and unstable mRNAs may, in part, be attributable to differences in steady-state poly(A) tail lengths.

scholarly journals Decomposition of time-dependent fluorescence signals reveals codon-specific kinetics of protein synthesis

2018 ◽  
Vol 46 (22) ◽  
pp. e130-e130 ◽  
Author(s):  
Nadin Haase ◽  
Wolf Holtkamp ◽  
Reinhard Lipowsky ◽  
Marina Rodnina ◽  
Sophia Rudorf
Keyword(s):  
Protein Synthesis ◽  
Time Dependent ◽  
Kinetics Of ◽  
Kinetics Of Protein Synthesis

An Interpretation on Kinetics of Martensitic Transformation

2011 ◽  
Vol 172-174 ◽  
pp. 90-98 ◽  
Author(s):  
Tomoyuki Kakeshita ◽  
Takashi Fukuda ◽  
Yong-Hee Lee
Keyword(s):  
Magnetic Field ◽  
Hydrostatic Pressure ◽  
Martensitic Transformation ◽  
Magnetic Fields ◽  
Martensitic Transformations ◽  
Phenomenological Theory ◽  
Time Dependent ◽  
Isothermal Process ◽  
Kinetics Of ◽  
Transformation Processes

We have investigated athermal and isothermal martensitic transformations (typical displacive transformations) in Fe–Ni, Fe–Ni–Cr, and Ni-Co-Mn-In alloys under magnetic fields and hydrostatic pressures in order to understand the time-dependent nature of martensitic transformation, that is, the kinetics of martensitic transformation. We have confirmed that the two transformation processes are closely related to each other, that is, the athermal process changes to the isothermal process and the isothermal process changes to the athermal one under a hydrostatic pressure or a magnetic field. These findings can be explained by the phenomenological theory, which gives a unified explanation for the two transformation processes previously proposed by our group.

Kinetics of Vascular and Extravascular Protein Exchange in Unbled and Bled Dogs

1955 ◽  
Vol 184 (1) ◽  
pp. 175-182 ◽  
Author(s):  
Karlman Wasserman ◽  
Jeanne D. Joseph ◽  
H. S. Mayerson
Keyword(s):  
Specific Activity ◽  
Blood Stream ◽  
Separate Entity ◽  
Approach To Equilibrium ◽  
Plasma Albumin ◽  
Compartment System ◽  
Specific Activities ◽  
Almost All ◽  
Kinetics Of ◽  
Extravascular Compartment

Unanesthetized, healthy greyhounds were infused with 25% albumin or bled, injected with I131-labeled albumin and albumin specific activities determined. It is shown that the albumin specific activity curves can be altered by changing the ratio of the vascular to extravascular albumin masses in a manner predicted from the mathematics of a two-compartment system. Increase of vascular albumin mass relative to extravascular mass results in a smaller initial disappearance of albumin specific activity from the blood stream and a faster approach to equilibrium. Decrease of vascular albumin mass relative to extravascular mass by bleeding shows that 50% of albumin replacement after hemorrhage appears to be accomplished within 24 hours. Almost all of this protein comes from the extravascular compartment. Rapid anabolism accounts for the replenishment of protein for the next 2–5 days, during and after which there is a reduced catabolism of the existing plasma albumin. The results indicate that an extravascular albumin mass exists as a separate entity and net movements may occur from this mass into the plasma when the equilibrium between the vascular and extravascular masses is disturbed.

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