scholarly journals Sample Preparation Report of the Fourth OPCW Confidence Building Exercise on Biomedical Sample Analysis

2014 ◽  
Author(s):  
R. N. Udey ◽  
T. H. Corzett ◽  
A. Alcaraz
2015 ◽  
Vol 1 (4) ◽  
pp. 426-447 ◽  
Author(s):  
Nevetha Yogarajah ◽  
Scott S. H. Tsai

Conception of a micro total analytical system (μTAS), capable of sample preparation, sample analysis, and signal acquisition, for portable trace arsenic detection.


2021 ◽  
Author(s):  
Sean Morgan-Jones ◽  
Pete Carleson ◽  
Mark Najarian ◽  
Gavin Mitchson ◽  
Noel Franco ◽  
...  

Abstract The development of advanced logic processing technologies has hit a critical slowing period over the past 10 years. Long gone are the booming days of exponential growth seen in chip transistor density as described by Moore's Law back in 1965.[1] With modern logic manufacturers now capable of creating transistors in the 5-7 nm node range, having the ability to isolate, inspect, and probe individual metal and via layers is of utmost importance for defect inspection and design validation. In this realm of failure analysis, it is critical that design manufacturers possess the ability to isolate any given single layer of their logic samples. These isolated layers can be inspected for defects via SEM, provide validation of CAD designs, or tested with electrical probing for failure analysis. The work here-in describes a functional workflow that enables manufacturers to perform this kind of sample preparation in an automated fashion using the Thermo Scientific™ Helios™ G5 PFIB platform. This workflow can be utilized by both the Thermo Scientific Full Wafer and Small Dual Beam PFIB platforms to streamline sample analysis and failure testing in both the lab and fabrication environments.


2021 ◽  
Author(s):  
Amir Ata Saei ◽  
Christian M. Beusch ◽  
Pierre Sabatier ◽  
Juan Astorga Wells ◽  
Hassan Gharibi ◽  
...  

Abstract This protocol describes the proteomics technique called System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis or SIESTA 1,2. SIESTA can be used for universal discovery of enzyme substrates that shift in thermal stability or solubility upon post-translational modification (PTM). Experimental design, proteomics sample preparation and data analysis are the key stages of this protocol. Data analysis can be performed using our SIESTA package hosted on GitHub 3. When performed with classical thermal proteome profiling (TPP), the protocol will take 5 days for sample preparation and 14 days of sample analysis by mass spectrometry (the current protocol). If our high-throughput version of TPP called Proteome Integral Solubility Alteration assay (PISA) 4 is used instead, the sample analysis time by mass spectrometry is reduced to 1-2 days for the same number of conditions.


2020 ◽  
Vol 19 (4) ◽  
pp. 537-544
Author(s):  
Nguyen Thi Hong Nhung ◽  
Nguyen Thi Thuy ◽  
Nguyen Viet Hien ◽  
Nguyen Huu Manh

Calcareous nannofossils are very small microfossils composed of calcium carbonate. They are very good biostratigraphic markers within marine sediments by covering the Jurassic to present. The standard preparation of a sample for nannofossil analysis requires the collection of the largest quantity and the best fossils. Sample preparation accords to the following steps: i. Pounding sample; ii. Eliminating organic matter; iii. Washing sample; iv. Filter sample through the sieve; v. Eliminating clay; vi. Drying sample in an incubator; vii. Packing sample. Sample analysis accords to the following steps: i. Preparation of smear - slide; ii. Observation of morphology; iii. Determination; iv. Taking photo; v. Evaluating overall preservation and abundance of fossils; vi. Making analysis result sheet. This process is applied to study calcareous nannofossils within marine sediments in Soc Trang province. It makes much clear to understand middle Pleistocene-early Holocene ecosystem of calcareous nannofossil. In conclusion, this assemblage belongs to NN21 zone by the present of Emiliania huxleyi and Gephyrocapsa oceanica.


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