scholarly journals Regional Difference of Muscle Oxygen Saturation and Blood Volume during Exercise Determined by Near Infrared Imaging Device.

2001 ◽  
Vol 51 (5) ◽  
pp. 599-606 ◽  
Author(s):  
Hajime Miura ◽  
Kevin McCully ◽  
Long Hong ◽  
Shoko Nioka ◽  
Britton Chance
Author(s):  
Adeola A. Sanni ◽  
Kevin K. McCully

NIRS uses the relative absorption of light at 850nm and 760nm, to determine skeletal muscle oxygen saturation. Previous studies have used the ratio of both signals to report muscle oxygen saturation. Purpose: To evaluate the different approaches used to represent muscle oxygen saturation, and to evaluate the pulsations of the O2heme and Heme signal. Method: Twelve participants, ages 20-29years were tested on the forearm flexor muscles using continuous wave NIRS at rest. Measurements were taken during 2-3mins rest, during physiological calibration (5-minuts Ischemia) and during reperfusion.  Results: There was a significant difference in pulse size between O2heme and Heme signal at the three locations (p < 0.05). Resting oxygen saturation was 58.8+9.2%, 69.6+3.9%, and 89.2+6.9% when calibrated using O2heme, TSI, and Heme, respectively.  Conclusion: The difference in magnitude of O2heme and Heme pulse with each heartbeat might suggest different anatomical locations of these signals, which propose calibrating with just one of the signals instead of the ratio of both. Calculations of physiological calibration must account for increased blood volume in the tissue, because of the changes in blood volume which appear to be primarily from the O2heme signal. Resting oxygen levels calibrated with Heme agrees with theoretical oxygen saturation.


2003 ◽  
Vol 17 (2-3) ◽  
pp. 549-558 ◽  
Author(s):  
Hajime Miura ◽  
Kevin McCully ◽  
Britton Chance

Near infrared spectroscopy (NIRS) is a developing technique that measures the balance between muscle oxygen consumption and oxygen supply that is noninvasive and potentially portable. Differential absorption of light in the 600−900 nm region detects the changes in small vessel hemoglobin oxygen saturation and blood volume. Recent developments include the combining of multiple light sources and photodetectors to provide “images” of oxygen saturation and blood volume of wide regions of muscle. Using multiple NIRS imaging device, we monitored localized muscle metabolism during various exercises in the field as well as in the laboratory. In healthy subjects, the regional differences in oxygen saturation and blood volume were detected in the medial head of the gastrocnemius muscle during a standing plantar flexion exercise, consistent with differences in intramuscular pressure. Patients with peripheral arterial disease (PAD) showed slower recovery for both oxygenation and blood volume after exercise. Treatment for PAD resulted in improvements in NIRS-measured recovery times. In summary, NIRS devices have the ability to detect and monitor impaired muscle circulation. In addition, NIRS devices with multiple channels have the potential to evaluate the regional differences in oxygen status. Multiple NIRS imaging devices have the potential to play an important role in monitoring exercise prescription and clinical uses.


Author(s):  
Jun Chen ◽  
Jianchen Tao ◽  
Dayan Ban ◽  
Michael G. Helander ◽  
Zhibin Wang ◽  
...  

2019 ◽  
Vol 4 (2) ◽  
pp. 28
Author(s):  
Adeola A. Sanni ◽  
Kevin K. McCully

Near-infrared spectroscopy (NIRS) uses the relative absorption of light at 850 and 760 nm to determine skeletal muscle oxygen saturation. Previous studies have used the ratio of both signals to report muscle oxygen saturation. Purpose: The purpose of this pilot study is to assess the different approaches used to represent muscle oxygen saturation and to evaluate the pulsations of oxygenated hemoglobin/myoglobin (O2heme) and deoxygenated hemoglobin/myoglobin (Heme) signals. Method: Twelve participants, aged 20–29 years, were tested on the forearm flexor muscles using continuous-wave NIRS at rest. Measurements were taken during 2–3 min rest, physiological calibration (5 min ischemia), and reperfusion. Ten participants were included in the study analysis. Results: There was a significant difference in pulse size between O2heme and Heme signals at the three locations (p < 0.05). Resting oxygen saturation was 58.8% + 9.2%, 69.6% + 3.9%, and 89.2% + 6.9% when calibrated using O2heme, the tissue oxygenation/saturation index (TSI), and Heme, respectively. Conclusion: The difference in magnitude of O2heme and Heme pulses with each heartbeat might suggest different anatomical locations of these signals, for which calibrating with just one of the signals instead of the ratio of both is proposed. Calculations of physiological calibration must account for increased blood volume in the tissue because of the changes in blood volume, which appear to be primarily from the O2heme signal. Resting oxygen levels calibrated with Heme agree with theoretical oxygen saturation.


NIR news ◽  
2012 ◽  
Vol 23 (8) ◽  
pp. 14-17 ◽  
Author(s):  
Daitaro Ishikawa ◽  
Kodai Murayama ◽  
Takuma Genkawa ◽  
Kimie Awa ◽  
Makoto Komiyama ◽  
...  

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