scholarly journals Two types of delayed rectifying K+ channels in atrial cells of guinea pig heart.

1990 ◽  
Vol 40 (4) ◽  
pp. 479-490 ◽  
Author(s):  
Minoru HORIE ◽  
Seiji HAYASHI ◽  
Chuichi KAWAI
Keyword(s):  
Guinea Pig ◽  
Guinea Pig Heart ◽  
K Channels ◽  
Atrial Cells

scholarly journals Vasopressin Inhibits Sarcolemmal ATP-Sensitive K+ Channels via V1 Receptors Activation in the Guinea Pig Heart

2002 ◽  
Vol 66 (3) ◽  
pp. 277-277 ◽  
Author(s):  
Masago Tsuchiya ◽  
Kunihiko Tsuchiya ◽  
Rumi Maruyama ◽  
Genzou Takemura ◽  
Shinya Minatoguchi ◽  
...  
Keyword(s):  
Guinea Pig ◽  
Guinea Pig Heart ◽  
K Channels

Mitochondrial Oxidation of p-N, N-Dimethylamino-β-Phenethylamine (DAPA)

1975 ◽  
Vol 33 ◽  
pp. 458-459
Author(s):  
W. Allen Shannon ◽  
Hannah L. Wasserkrug ◽  
andArnold M. Seligman
Keyword(s):  
Guinea Pig ◽  
Oxidase Activity ◽  
Amine Oxidase ◽  
Histochemical Demonstration ◽  
Guinea Pig Heart ◽  
Pig Kidney ◽  
Cytoplasmic Vacuoles ◽  
Liver And Kidney ◽  
Mitochondrial Oxidation ◽  
Amine Oxidase Activity

The synthesis of a new substrate, p-N,N-dimethylamino-β-phenethylamine (DAPA)3 (Fig. 1) (1,2), and the testing of it as a possible substrate for tissue amine oxidase activity have resulted in the ultracytochemical localization of enzyme oxidase activity referred to as DAPA oxidase (DAPAO). DAPA was designed with the goal of providing an amine that would yield on oxidation a stronger reducing aldehyde than does tryptamine in the histochemical demonstration of monoamine oxidase (MAO) with tetrazolium salts.Ultracytochemical preparations of guinea pig heart, liver and kidney and rat heart and liver were studied. Guinea pig kidney, known to exhibit high levels of MAO, appeared the most reactive of the tissues studied. DAPAO reaction product appears primarily in mitochondrial outer compartments and cristae (Figs. 2-4). Reaction product is also localized in endoplasmic reticulum, cytoplasmic vacuoles and nuclear envelopes (Figs. 2 and 3) and in the sarcoplasmic reticulum of heart.

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