scholarly journals Studies on collagenase activity in patients with rheumatoid arthritis - Relationship of immune complex, IgG-rheumatoid factor and prostaglandin E2 level.

1986 ◽  
Vol 75 (4) ◽  
pp. 488-494
Author(s):  
Fusao SEKINE ◽  
Toshiyuki FUKUSHIMA ◽  
Minoru TABATA ◽  
Hideki SATOU ◽  
Isao OHNO ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Prostaglandin E2 ◽  
Rheumatoid Factor ◽  
Immune Complex ◽  
Collagenase Activity ◽  
Igg Rheumatoid Factor ◽  
Relationship Of

Relationship of HLA-DRB1 Alleles and Rheumatoid Arthritis in West South of Iran

2017 ◽  
Vol 9 (03) ◽  
Author(s):  
Karim Mowla ◽  
Elham Rajaee M. D. ◽  
Mehrdad Dargahi-MalAmir M. D. ◽  
Neda Yousefinezhad ◽  
Maryam Jamali Hondori
Keyword(s):  
Rheumatoid Arthritis ◽  
Environmental Factors ◽  
Rheumatoid Factor ◽  
Dna Extraction ◽  
Wrist Joint ◽  
Blood Sampling ◽  
Healthy Controls ◽  
Relationship Of ◽  
Synovial Pannus

Background: Rheumatoid arthritis is a systemic multifactor disease that presented with symmetrical polyarthritis more preferably in small wrist joint and ankle. Synovial pannus cause destruction and deformities in joints. The main reason of this disease in unknown, but past researchesshowed that genetically factor play important role beside environmental factors in susceptibility to this entity. Method:100 patients with rheumatoid arthritis diagnosed upon ACR 2010 criteria enrolled study. 92 healthy patents also enrolled DNA studying. of both group was extracted through DNA extraction kits by blood sampling. HLA-DRB1 typing was done by PCR-SSP method. Results: There were no significant differences in HLADRB1 *04, HLADRB1*08 and HLADRB1*11 alleles presentation between patients and healthy controls. Only there were statically significant correlation between HLA-DRB1*08 and Rheumatoid factor positive patents. (P = 0.025).

IgG-rheumatoid factor in seronegative rheumatoid arthritis

1983 ◽  
Vol 12 (sup52) ◽  
pp. 79-79
Author(s):  
T. Palosuo ◽  
K. Aho ◽  
V. Raunio ◽  
K. Kaarela
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Igg Rheumatoid Factor

IgG RHEUMATOID FACTOR IN PURIFIED IgG FRACTIONS AND WHOLE SERA FROM PATIENTS WITH RHEUMATOID ARTHRITIS

Rheumatology ◽  
1989 ◽  
Vol 28 (3) ◽  
pp. 227-232
Author(s):  
N. HARATS ◽  
A. RUBINOW ◽  
R. FISCHEL ◽  
D. EILAT
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Igg Rheumatoid Factor

scholarly journals RHEUMATOID FACTOR AND THE PATHOGENESIS OF RHEUMATOID ARTHRITIS

1961 ◽  
Vol 113 (2) ◽  
pp. 475-484 ◽  
Author(s):  
Robert C. Mellors ◽  
Adam Nowoslawski ◽  
Leonhard Korngold ◽  
Beth L. Sengson
Keyword(s):  
Rheumatoid Arthritis ◽  
Lymph Nodes ◽  
Rheumatoid Factor ◽  
Immune Complex ◽  
Germinal Center ◽  
Plasma Cells ◽  
Fluorescent Antibody ◽  
Serological Tests ◽  
Cellular Origin ◽  
And Function

In analogy with the two categories of reactants which are used in the serological tests for the unusual category of macroglobulins called rheumatoid factor, two fluorescent reactants have been prepared for the detection of rheumatoid factor in situ in tissue sections: fluorescent antigen-rabbit antibody (immune) complex, in the present study, and fluorescent aggregated human γ-globulin, in previous work. Plasma cells in the synovial membrane and germinal center cells and internodular plasma cells in lymph nodes are the sites of origin of rheumatoid factor in active rheumatoid arthritis, whether occurring in adults or children. Plasma cells and germinal center cells which form rheumatoid factor detectable with fluorescent immune complex are less numerous than those which contain factor demonstrable with fluorescent aggregate. In the same tissues, plasma cells and germinal center cells which contain macroglobulin (19S human γ-globulin) detectable with fluorescent antibody—but not showing the reactivity of rheumatoid factor—are more abundant than those containing rheumatoid factor. While macroglobulin and rheumatoid factor are almost exclusively formed in the cytoplasm, these proteins are also detectable in the nucleus of an occasional plasma cell. Normal and pathological synovial and capsular tissues, lymph nodes, and connective tissues obtained from individuals without rheumatoid arthritis are not stained with fluorescent immune complex or, except for an unusual example of Waldenstrom's macroglobulinemia, with fluorescent aggregate. The cellular origin, as well as certain chemical and immunological attributes, of rheumatoid factor suggests an antibody-like nature and function. The observations cited are consistent with the behavior anticipated for cellular rheumatoid factor, were it primarily an antibody direct to an altered human γ-globulin and cross-reacting with rabbit γ-globulin. However, it is also possible that there are two or more cellular rheumatoid factors. Lesion-associated protein precipitates having the composition anticipated for rheumatoid factor-antigen complex are localized in the amyloid depositions in kidney and spleen of an individual who died with amyloidosis secondary to rheumatoid arthritis.

scholarly journals IgG Rheumatoid Factor in Synovial Fluid of Patients with Rheumatoid Arthritis.

1998 ◽  
Vol 47 (2) ◽  
pp. 693-697
Author(s):  
Minoru Ikeda ◽  
Toshio Inoue ◽  
Takashi Ishinishi ◽  
Kosuke Ogata
Keyword(s):  
Rheumatoid Arthritis ◽  
Synovial Fluid ◽  
Rheumatoid Factor ◽  
Igg Rheumatoid Factor

scholarly journals Increased IgG Rheumatoid Factor-Positivity in the Asian Rheumatoid Arthritis Patients Irrespective of Ethnicity

2014 ◽  
Vol 04 (01) ◽  
pp. 43-51 ◽  
Author(s):  
Chun Lai Too ◽  
Johan Rönnelid ◽  
Yuslina Mat Yusoff ◽  
Jasbir Singh Dhaliwal ◽  
Nor Ashikin Jinah ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Igg Rheumatoid Factor

scholarly journals A study of IgG-rheumatoid factor in the serum of patients with rheumatoid arthritis.

1993 ◽  
Vol 16 (2) ◽  
pp. 132-139
Author(s):  
Shigeo Aoki ◽  
Kohzoh Imai ◽  
Miyuki Yamamura ◽  
Masayuki Tsujisaki ◽  
Toshiroh Sugiyama ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Factor ◽  
Igg Rheumatoid Factor
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