scholarly journals Histopathological Findings of Cystic Endometrial Morphology Based on Ultrasonographic Imaging in Premenopausal Women

2018 ◽  
pp. 1
Author(s):  
Tugba Kinay ◽  
Metin Kaplan ◽  
Fulya Kayikcioglu ◽  
Jale Karakaya
Keyword(s):  
Endometrial Hyperplasia ◽  
Care Center ◽  
Tertiary Care ◽  
Premenopausal Women ◽  
Binary Logistic Regression ◽  
Endometrial Biopsy ◽  
Binary Logistic Regression Analysis ◽  
Chi Square ◽  
Histopathological Findings ◽  
Chi Square Test

<p><strong>Objective:</strong> To evaluate the histopathological findings of cystic endometrial morphology based on ultrasonographic imaging in premenopausal women.</p><p><strong>Study Design:</strong> The medical records of 3607 premenopausal women that underwent ultrasonographic examination at a tertiary care center were reviewed, as were endometrial biopsy findings in 816 of the women. These 816 women were divided in 2 groups according to ultrasonographic endometrial findings: the cystic group and the non-cystic group. Clinical and histopathological findings in the 2 groups were compared. Statistical analysis was performed using independent samples t test, chi-square test, and binary logistic regression analysis.</p><p><strong>Results:</strong> Three hundred and eighty one (46.7%) of the women that underwent endometrial biopsy had cystic endometrium, whereas 435 (53.3%) had non-cystic endometrium. The most common histopathological finding in the cystic group was endometrial hyperplasia without atypia (44.6%). Cystic morphology was nearly 8-fold more common in the women with endometrial hyperplasia without atypia (95% CI: 5.43-11.67). The premalignant and malignant pathology rates in the cystic group and non-cystic group were similar (1.1% vs. 0.5% [p=0.426] and 0.8% vs. 0.5% [p=0.669], respectively). Secretory endometrium was less common in the cystic group than in the non-cystic group (5.0% vs. 37.9% [p&lt; 0.001])</p><p><strong>Conclusion:</strong> Cystic endometrial morphology based on ultrasonographic imaging was more common in women with endometrial hyperplasia without atypia. There wasn’t an association between cystic endometrium and other endometrial pathologies or functional endometrium. <br />Keywords: Cystic endometrium, Endometrium, Endometrial hyperplasia, Premenopausal, Ultrasonography</p>

scholarly journals Correlation of Hormonal Profile and Lipid Levels with Female Adult Acne in a Tertiary Care Center of Nepal

2018 ◽  
Vol 16 (2) ◽  
pp. 222-227 ◽  
Author(s):  
Smriti Shrestha
Keyword(s):  
Lipid Profile ◽  
Clinical Symptoms ◽  
Care Center ◽  
Tertiary Care ◽  
Thyroid Stimulating Hormone ◽  
Bivariate Analysis ◽  
Female Adult ◽  
Chi Square ◽  
Chi Square Test ◽  
Relationship Of

 Background: Acne beyond 25 years of age is frequently associated with hormonal derangement in women. Hormonal association provides the impetus for hormonal therapy as well as underpins the need for blood investigations in this population. Hence, we aim to estimate the presence of hormonal derangement and lipid alteration in female adult acne.Methods: A prospective, observational study was conducted in Dhulikhel Hospital from July 2015 to February 2016. Females older than 25 years with acne were taken in the study after informed consent. Total 100 patients were enrolled aftersample sizeestimation. Hormonal paneland lipid profile were measured. Hormones tested were androgens, C-peptide and thyroid stimulating hormone. Data analysis was done with SPSS-23. Bivariate analysis was done by chi-square test for categorical data.Results: In this study, majority of patients were younger than 30 years (70.5%) and perioral area most commonly involved. Hormonal alteration was seen in 37.2% patients, among which 17.9% had hyperandrogenism, 15.4% had abnormal thyroid level and 10.3% had high C-peptides respectively. Lipid profile was altered in 15.4% patients. Hormonal alteration had significant association with irregular menstruation (P<0.05) but not acne severity.Conclusions: We observed hormonal alteration frequently in females with adult acne, which comprised of various hormonal parameters including hyperandrogenism. Hormonal alteration reflects deranged metabolic milieu and we suggestthat wide hormonal panel should be done in female adult acne. Relationship of hormones with menstrual irregularity but not with acne severity, suggest that clinical symptoms should lead hormonal investigations in all grades of acne.

Validation of a Breastfeeding History Questionnaire for the Risk of In-Hospital Formula Supplementation Among Multiparous Women

2019 ◽  
Vol 35 (4) ◽  
pp. 665-671
Author(s):  
Whitney R. Bender ◽  
Nathanael C. Koelper ◽  
Mary D. Sammel ◽  
Celeste Durnwald
Keyword(s):  
Hospital Stay ◽  
Care Center ◽  
Tertiary Care ◽  
Categorical Variables ◽  
Chi Square ◽  
Multiparous Women ◽  
Chi Square Test ◽  
Student’S T ◽  
Relationship Of ◽  
The Relationship

Background: A woman’s prior breastfeeding history may influence future decisions regarding infant feeding. Few quantitative tools utilizing this information have been demonstrated to predict breastfeeding success. Research aim: To evaluate the efficacy of a prenatal breastfeeding history (BAP) questionnaire administered in prenatal care to predict in-hospital formula supplementation among multiparous women. Methods: This is a prospective observational study of multiparous women with singleton pregnancies who presented to a Baby-Friendly urban tertiary care center for 1st prenatal visit at < 20 weeks’ gestation. The BAP tool generates a numerical score, with higher score (≥ 2) indicating prior successful breastfeeding experiences. The primary outcome was occurrence of non-medically indicated formula supplementation during the postpartum hospital stay. Student’s t test and Pearson’s chi-square test were used to compare continuous and categorical variables. A multivariable logistic regression was performed to assess the relationship of BAP score to formula supplementation. Of 587 women screened, 433 (73.8%) mother–infant dyads were analyzed. Results: Rates of formula supplementation in women with BAP scores ≤ 1 were 67% (156/234) compared with 37% (73/199) in women with higher scores ( p < 0.0001). After controlling for race/ethnicity, insurance, and obesity, women with BAP scores of ≤ 1 were 2.6 times more likely to supplement formula than women with higher scores (a OR 2.62, 95% CI [1.70, 4.04], p < .0001). Conclusion: In this prospective validation study, women with negative prior breastfeeding experiences, as evidenced by a lower BAP score, were more likely to supplement formula during the postpartum hospital stay.

scholarly journals Types and Patterns of Colonic Polyps Encountered at a Tertiary Care Center in a Developing Country in South Asia

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Dakshitha Praneeth Wickramasinghe ◽  
Sanjeev F. Samaranayaka ◽  
Chamila Lakmal ◽  
Sashi Mathotaarachchi ◽  
Chula Kanishka Lal ◽  
...  
Keyword(s):  
Care Center ◽  
Tertiary Care ◽  
Colonic Polyps ◽  
Colorectal Polyps ◽  
Tubular Adenoma ◽  
Tubulovillous Adenoma ◽  
Chi Square ◽  
Chi Square Test ◽  
Pathology Reports ◽  
Spearman’S Correlation

Purpose. To identify the prevalence, types, and patterns of colonic polyps in a cohort of patients presenting to a tertiary care referral center in Sri Lanka.Methods. Endoscopy and pathology reports of a single unit from 2006 to 2013 were analyzed retrospectively. Spearman’s correlation coefficient and chi-square test were used to identify correlations.Results. There were a total of 158 patients (M : F, 10 : 57) who had polyps encountered on colonoscopy (n=1408) and flexible sigmoidoscopy (n=2402) with an incidence of 4.1%. Mean age was 56.5 years (SD 16.4) and the incidence of polyps increased with age. The majority (81.6%) had one polyp. A total of 188 polyps were assessed and most were seen in the rectum (33.5%) followed by sigmoid colon (22.9%). The commonest histological type was tubulovillous adenoma (33.5%) followed by tubular adenoma (24.5%). Most polyps were benign (91.5%). There was no statistically significant correlation with age or gender with malignancy, site, or histology.Discussion and Conclusion. The incidence of colorectal polyps was lower than the values reported in the west. More polyps were identified in males. There was no statistically significant association between age, gender, or multiplicity and malignant change in the polyps.

scholarly journals The contingent valuation for the preservation of three urban green parks

2020 ◽  
Vol 11 (3) ◽  
pp. 251-263
Author(s):  
José Francisco dos Reis Neto ◽  
Michelle Da Rosa Lopes ◽  
Celso Correia de Souza ◽  
Marlucy Ferreira Machado Xavier
Keyword(s):  
Natural Resources ◽  
Binary Logistic Regression ◽  
Well Being ◽  
Environmental Conservation ◽  
Local Economy ◽  
Environmental Research ◽  
Binary Logistic Regression Analysis ◽  
Chi Square ◽  
Urban Green ◽  
Chi Square Test

Urban green parks, considered as natural resources, should be seen as strategic elements for conservation of natural resources, socialization, health and well-being, since it significantly influences the local economy. The research sought to quantify the Willingness to Pay (WTP) for environmental conservation and its influencing factors, indicated by the population using three urban parks in Campo Grande, MS, Brazil: Parque das Nações Indígenas (PNI); Parque Ayrton Senna (PAS); and Parque Matas do Segredo (PMS). It was a quantitative approach, interviewing 824 users from the three parks object of the research, highlighting those who know and frequent the parks. A structured questionnaire was used, divided into groups of variables to identify the perceptions of socioeconomic, maintenance and preservation of parks, satisfaction with the equipment offered, and with the environmental preservation and maintenance of the Parks. Descriptive statistics and Chi-square test were used to compare the independence between the proportions obtained for each Park, at the level of significance at p <0.05, bilateral. A binary logistic regression analysis of discrete variables was also performed to identify the factors that may influence the user of the Park to WTP of environmental conservation. As a result, it was identified that there is satisfaction in the Parks, in relation to the questions: place for social interaction, appearance, attractiveness, calm, cozy, beautiful and clean environment. In relation to WTP, it was identified that the people who attend the Parks are willing to pay for the protection and environmental conservation of these. This article has its academic importance in contributing to the knowledge of the importance of Urban Green Parks, as well as providing indications for the evolution of others socio-environmental research projects. Under the business scope, it provides data and conclusions for the direction of public policies enlist the population and entrepreneurs to strengthen the preservation and maintenance.

scholarly journals DETERMINANTS OF INCOME SECURITY AMONG PENSIONABLE RETIRED PERSONS IN KENYA

2020 ◽  
Vol 11 (1) ◽  
pp. 24-34
Author(s):  
Lucy Maina ◽  
Elishiba Kimani
Keyword(s):  
Logistic Regression ◽  
Binary Logistic Regression ◽  
Binary Logistic Regression Analysis ◽  
Retirement Savings ◽  
Chi Square ◽  
Income Security ◽  
Financial Status ◽  
Chi Square Test ◽  
Test Of Significance ◽  
Logistic Regression Procedure

Retirees’ income security constitutes a key concern for nations aiming to secure their ageing populations. Kenya has a growing retirement sector with about 252,000 retired civil servants who are on pension and a significant number of private sector retirees who receive a gratuity at retirement. Though formally retired workers may receive a pension, studies consistently report low pensions uptake and inadequate incomes for those retired as well as an increasing national and societal burden. This paper explores the key determinants of income security among 978retired persons who were receiving dues on their retirement savings. Guided by the life cycle and third age theory, the study investigated whether retirees’ socio-economic attributes, pre-retirement financial status, retirees’ benefit package, retirees’ utilization of retirement savings and investments and pre-retirement preparation correlated with income security. A mixed-method study design was used combining survey and case study approaches. Cluster, purposive and random sampling methods were employed to select retirees under the four categories of retirement schemes in Kenya across 18 selected counties of Kenya. Hypotheses were tested using the Chi square test of significance and comparison of means (t-test) specifically to illustrate the relationship between socio-economic indicators, pre-retirement factors and income security at retirement. Logistic regression procedure was employed to isolate the significant factors that predict income security in retirement. The binary logistic regression analysis confirm that retirees with higher education had 26% higher chances of enjoying income security, those who earned higher pre-retirement salary had 25% higher chances of having a secure income at retirement, those knowledgeable about pensions had 35% higher chances of being income secure while those who had planned for their retirement had 14% higher chances of achieving income security. The study recommends crafting of a robust retirement planning package, financial and health plans for retirees’ income security and sustainable livelihoods.

scholarly journals Predictors of Death in Severe COVID-19 Patients at Millennium COVID-19 Care Center in Ethiopia: A Case-Control Study

2020 ◽  
Author(s):  
Endalkachew H. Maru ◽  
Tigist W. Leulseged ◽  
Ishmael S. Hassen ◽  
Wuletaw C. Zewde ◽  
Nigat W. Chamesew ◽  
...  
Keyword(s):  
Case Control Study ◽  
Care Center ◽  
Binary Logistic Regression ◽  
Case Control ◽  
P Value ◽  
Chi Square ◽  
P Values ◽  
Significant Difference ◽  
Chi Square Test ◽  
Control Study

ABSTRACTBackgroundAs the number of new cases and death due to COVID-19 is increasing, understanding the characteristics of severe COVID-19 patients and identifying characteristics that lead to death is a key to make an informed decision. In Ethiopia, as of September 27, 2020, a total of 72,700 cases and 1165 deaths were reported.ObjectiveThe study aimed to assess the determinants of death in Severe COVID-19 patients admitted to Millennium COVID-19 Care Center in Ethiopia.MethodsA case-control study of 147 Severe COVID-19 patients (49 deaths and 98 discharged alive cases) was conducted from August to September 2020. A comparison of underlying characteristics between cases (death) and controls (alive) was assessed using a chi-square test and an independent t-test with a p-value of <0.05 considered as having a statistically significant difference. Multivariable binary logistic regression was used to assess a statistically significant association between the predictor variables and outcome of Severe COVID-19 (Alive Vs Death) where Adjusted Odds ratio (AOR), 95% CIs for AOR, and P-values were used for testing significance and interpretation of results.ResultsHaving diabetes mellitus (AOR= 3.257, 95% CI= 1.348, 7.867, p-value=0.00), fever (AOR=0.328, 95% CI: 0.123, 0.878, p-value= 0.027) and Shortness of breath (AOR= 4.034, 95% CI= 1.481, 10.988, p-value=0.006) were found to be significant predictors of death in Severe COVID-19 patients.ConclusionsThe outcome of death in Severe COVID-19 patients is found to be associated with exposures to being diabetic and having SOB at admission. On the other hand, having a fever at admission was associated with a favorable outcome of being discharged alive.

scholarly journals Prevalence of uterine lesions associated with leiomyomas and role of endometrial biopsy in management

2020 ◽  
Vol 9 (7) ◽  
pp. 2828
Author(s):  
Minal J. Kumbhalwar ◽  
Anuradha Konda
Keyword(s):  
Endometrial Hyperplasia ◽  
Clinical History ◽  
Endometrial Biopsy ◽  
P Value ◽  
Chi Square ◽  
Qualitative Variable ◽  
Chi Square Test ◽  
Risk Patients ◽  
Observational Cohort

Background: Present study highlights association between symptomatic patients of fibroids and its coexistence with pathologies like endometriosis, adenomyosis, polyp, endometrial hyperplasia and carcinoma. The aim was evaluating role of endometrial biopsy before surgery.Methods: The study was observational cohort, conducted on women operated for fibroid or recently diagnosed with fibroid. 150 women were included. Histopathology reports of already operated were analysed for association between uterine pathology and fibroid. In prospective cases ultrasonography findings was noted and patients having leiomyoma underwent biopsy and reports studied for association. Chi-square test done to find association between qualitative variable and p value <0.05 considered significant.Results: Out of 150, 24.6% had adenomyosis, 14% had endometrial hyperplasia in which 2% had atypia and 12% without atypia, 8.6% had cervical polyp, 5.33% had endometrial polyp, 4% had endometriosis while 42.7% had no association.Conclusions: This study revealed increasing trend of coexistence of leiomyomas with uterine pathologies. Early identification of endometrial pathologies on clinical history and imaging helps in selection of high-risk patients who need biopsy to rule out malignancy thus avoiding routine D and C which is done for every case.

scholarly journals Determinants of Developing Symptomatic Disease in Ethiopian COVID-19 Patients

2020 ◽  
Author(s):  
Tigist W. Leulseged ◽  
Degu G. Alemahu ◽  
Ishmael S. Hassen ◽  
Endalkachew H. Maru ◽  
Wuletaw C. Zewde ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Management Practice ◽  
Care Center ◽  
Severe Disease ◽  
Binary Logistic Regression ◽  
P Value ◽  
Chi Square ◽  
Symptomatic Disease ◽  
Significant Difference ◽  
Chi Square Test

ABSTRACTBackgroundStudies show that having some symptoms seems to be associated with more severe disease and poor prognosis. Therefore, knowing who is more susceptible to symptomatic COVID-19 disease is important to provide targeted preventive and management practice. The aim of the study was to assess the determinants of having symptomatic disease among COVID-19 patients admitted to Millennium COVID-19 Care Center in Ethiopia.MethodsA case-control study was conducted from August to September 2020 among a randomly selected 765 COVID-19 patients (372 Asymptomatic and 393 Symptomatic patients). Chi-square test and independent t-test were used to detect the presence of a statistically significant difference in the characteristics of the cases (symptomatic) and controls (asymptomatic), where p-value of <0.05 considered as having a statistically significant difference. Multivariable binary logistic regression was used to assess a statistically significant association between the independent variables and developing symptomatic COVID-19 where Adjusted Odds ratio (AOR), 95% CIs for AOR, and P-values were used for testing significance and interpretation of results.ResultsThe result of the multivariable binary logistic regression shows that age group (AOR= 1.818, 95% CI= 1.210, 2.731, p-value=0.004 for 30-39 years; AOR= 1.611, 95% CI= 1.016, 2.554, p-value=0.043 for 40-49 years and AOR= 4.076, 95% CI= 2.582, 6.435, p-value=0.0001 for years and above), sex (AOR= 1.672, 95% CI= 1.216, 2.299, p-value=0.002) and history of diabetes mellitus (AOR= 2.406, 95% CI= 1.384, 4.181, p-value=0.002) were found to be significant factors that determine the development of symptomatic disease in COVID-19 patients.ConclusionsDeveloping a symptomatic COVID-19 disease was found to be determined by exposures of old age, male sex, and being diabetic. Therefore, patients with the above factors should be given enough attention in the prevention and management process, including inpatient management, to pick symptoms earlier and to manage accordingly so that these patients can have a favorable treatment outcome.

scholarly journals COVID-19 with early neurological and cardiac thromboembolic phenomena—timeline of incidence and clinical features

2021 ◽  
Author(s):  
Uma Sundar ◽  
Sanah Merchant ◽  
Meera Shah ◽  
Amita Mukhopadhyay ◽  
Shaonak Kolte ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Binary Logistic Regression ◽  
Case Control ◽  
Respiratory Support ◽  
Binary Logistic Regression Analysis ◽  
Case Group ◽  
Control Analysis ◽  
Chi Square ◽  
Coronary Syndrome ◽  
Case Control Analysis

Background: At our tertiary care public hospital, we saw COVID-19 presenting with thromboembolic phenomena, indicating a possible early thrombo-inflammatory pathology. Objectives: We documented patients with cardiac and neurological thromboembolic phenomena as a primary presentation of COVID-19, and compared a subset of COVID associated strokes against COVID-19 patients without thrombotic manifestations. Methods: We included all COVID-Stroke and COVID-ACS (COVID-19, with ischemic arterial stroke/Acute Coronary Syndrome presenting prior to/simultaneous with/within 72 hours of systemic/respiratory COVID manifestations) admitted from April to November 2020. In the nested case control analysis, we used unpaired T-test and chi-square test to study differences between COVID-Strokes (case group) and non-thrombotic COVID controls. Results and Conclusions: We noted 68 strokes and 122 ACS associated with COVID-19. ACS peaked in May-June, while stroke admissions peaked later in September-October, possibly because severe strokes may have expired at home during the lockdown. In the case-control analysis, cases (n=43; 12F:31M; mean age 51.5 years) had significantly higher D-Dimer values than controls (n=50; 9F:41M; mean age 51.6 years). Mortality was significantly higher in cases (51.2% vs. 26.0%; p = 0.018). We noted 7.5 times higher mortality in cases versus controls even among patients needing minimal oxygen support. Imaging in 37 patients showed both anterior and posterior circulation territories affected in seven, with almost half of Carotid territory strokes being large hemispherical strokes. Additionally, CT/MRI angiography in 28 strokes showed large vessel occlusions in 19 patients. Death in cases thus probably occurred before progression to intense respiratory support, due to severe central nervous system insult. Binary logistic regression analysis showed respiratory support intensity to be the sole independent predictor of mortality among cases. Respiratory distress could have been due to COVID-19 lung infection or aspiration pneumonia resulting from obtunded sensorium. In controls, mortality was predicted by increasing age, female sex, and respiratory support intensity.

scholarly journals Analysis of Risk Factors with the Degree of Pelvic Organs Prolapse at Dr. Mohammad Hoesin General Hospital Palembang

2021 ◽  
Vol 5 (4) ◽  
pp. 915-918
Author(s):  
Hadrians Kesuma Putra ◽  
Callista Zahra Aidi ◽  
M. Zulkarnain
Keyword(s):  
Risk Factors ◽  
Pelvic Organ Prolapse ◽  
General Hospital ◽  
Binary Logistic Regression ◽  
Pelvic Organ ◽  
Binary Logistic Regression Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
Pelvic Organs ◽  
Chi Square Test

Background. Pelvic organ prolapse (POP) is a condition in which one or more pelvic organs (consisting of the uterus, vaginal cuff, bladder, intestines, and rectum) or more are still in or out of the vagina. Risk factors that influence the incidence of POP consist of obstetric risk factors (number of parity and birth method) and non-obstetric risk factors (age, menopause, BMI, comorbid disease, and hypertension). The purpose of this study was to analyze the risk factors associated with the degree of POP. Methods. This study is an observational study with a cross-sectional approach to 111 patients examined at the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin general hospital Palembang on January 2017 to December 2019, who was diagnosed with pelvic organ prolapse. Results. The results showed the effect of variables with the degree of POP using the chi-square test, consisting of parity (p=0.007), birth method (p=<0.001), age (p=0.016), menopause (p=0.001), BMI (p =0.005), indicates that there is a significant effect on the degree of POP. Meanwhile, comorbid factors (p=0.481) and hypertension (p=0.415) did not show a significant relationship with the degree of POP. The results of the binary logistic regression analysis of all risk factors, the number of parity >4, overweight, and age 40 years, will have a 99.85% chance of experiencing grade 3 or 4 prolapse. Conclusion. Age is the most dominant risk factor affecting the degree of pelvic organ prolapse, with 19 times the chance of developing POP 3 or 4 degrees.

Sign in / Sign up

Export Citation Format

Share Document