scholarly journals Reference Ranges of Serum Blood Urea Nitrogen, Creatinine Concentration and Ultrasonographic Measurement of the Kidneys in Term Healthy Newborns in the Neonatal Period

2017 ◽  
Vol 23 (3) ◽  
pp. 163
Author(s):  
Şebnem Kader ◽  
Mehmet Mutlu ◽  
Elif Bahat Özdoğan ◽  
Yakup Aslan ◽  
İlker Eyüpoğlu ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Birth Weight ◽  
Blood Urea Nitrogen ◽  
Kidney Injury ◽  
Kidney Volume ◽  
Reference Ranges ◽  
Urea Nitrogen ◽  
Positive Correlation ◽  
Significant Difference ◽  
Serum Blood Urea Nitrogen

<p><strong>Objective:</strong> Acute kidney injury is an important problem in neonates. We conducted a cross-sectional prospective study to determine normal serum blood urea nitrogen, creatinine reference ranges and ranges of ultrasonographic measurement of kidneys in healthy term newborns.</p><p><br /><strong>Study Design:</strong> Blood samples were collected from total 357 healthy newborns at birth (n=45), 1st (n=30), 3rd (n=61), 7th (n=34), 10th (n=132), 14th (n=36), and 28th (n=19) days of life. Renal ultrasonographic was performed by the same two radiologists on 81 newborns aged 10 days. <br /><strong></strong></p><p><strong>Results:</strong> Serum blood urea nitrogen and creatinine concentrations have reached to the highest level at the first day of life and have returned to cord level at the third day of life. There were gradually decrease in serum blood urea nitrogen and creatinine levels after the first day of life. There were significant difference in both right and left renal length, width, and volumes in terms of gender and these parameters were statistically higher in boys than girls (p&lt;0.05). Birth weight of the boys (3548±539g) was statistically higher than girls (3307±405 g) (p=0.028). There was a positive correlation between birth weight and right (r=0.38, p=0.000) and left kidney volumes (r=0.44, p=0.000).</p><p><strong>Conclusion:</strong> Our findings showed that measured blood urea nitrogen and creatinine levels changed in accordance with postnatal days and there was a positive correlation between kidney volume and birth weight of newborns. We concluded that these findings are important for evaluation of acute kidney injury and for screening of for urinary tract anomalies in neonates</p>

Saliva Urea Nitrogen Continuously Reflects Blood Urea Nitrogen after Acute Kidney Injury Diagnosis and Management: Longitudinal Observational Data from a Collaborative, International, Prospective, Multicenter Study

2016 ◽  
Vol 42 (1) ◽  
pp. 64-72 ◽  
Author(s):  
Jochen G. Raimann ◽  
Viviane Calice-Silva ◽  
Stephan Thijssen ◽  
Fabiana Baggio Nerbass ◽  
Marcos A. Vieira ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Blood Urea Nitrogen ◽  
Diagnostic Performance ◽  
Journal Club ◽  
Kidney Injury ◽  
The United States ◽  
Operating Characteristics ◽  
Urea Nitrogen ◽  
Acute Kidney Injury Diagnosis ◽  
Monitoring Treatment

Background: Acute kidney injury (AKI) is a growing global concern and often reversible. Saliva urea nitrogen (SUN) measured by a dipstick may allow rapid diagnosis. We studied longitudinal agreement between SUN and blood urea nitrogen (BUN) and the diagnostic performance of both. Methods: Agreement between SUN and BUN and diagnostic performance to diagnose AKI severity in AKI patients in the United States and Brazil were studied. Bland-Altman analysis and linear mixed effects models were employed to test the agreement between SUN and BUN. Receiver operating characteristics statistics were used to test the diagnostic performance to diagnose AKI severity. Results: We found an underestimation of BUN by SUN, decreasing with increasing BUN levels in 37 studied patients, consistent on all observation days. The diagnostic performance of SUN (AUC 0.81, 95% CI 0.63-0.98) was comparable to BUN (AUC 0.85, 95% CI 0.71-0.98). Conclusion: SUN reflects BUN especially in severe AKI. It also allows monitoring treatment responses. Video Journal Club ‘Cappuccino with Claudio Ronco' at http://www.karger.com/?doi=445041.

scholarly journals Kejadian Acute Kidney Injury dengan Kriteria pRIFLE pada Unit Perawatan Intensif Anak Rumah Sakit Sanglah Denpasar

Sari Pediatri ◽  
2016 ◽  
Vol 14 (3) ◽  
pp. 158
Author(s):  
GAP Nilawati
Keyword(s):  
Acute Kidney Injury ◽  
Blood Urea Nitrogen ◽  
Kidney Injury ◽  
Urea Nitrogen

Latar belakang.Acute kidney injury(AKI) merupakan merupakan suatu keadaan yang dapat meningkatkan angka morbiditas dan mortalitas pada anak yang dirawat di rumah sakit terutama dengan perawatan intensif.Tujuan.Mengetahui kejadian AKI pada anak yang mendapat perawatan di Unit Perawatan Intensif Anak.Metode.Penelitian deskriptif retrospektif dengan mengambil data dari rekam medis dan register perawatan ruang intensif selama tahun 2010Hasil.Dari 411 pasien yang dirawat di Unit Perawatan Intensif Anak, 149 (36,25%) dilakukan pemeriksaan blood urea nitrogen(BUN) dan serum kreatinin (SC). Terdapat 25 kasus (6,1%) merupakan kasus AKI. Sebagian besar subyek berusia di bawah 1 tahun (10/25) dan berjenis kelamin laki-laki 15/25. Berdasarkan kriteria pRIFLE, 3 termasuk dalam kriteria risk (R),12 injury (I),dan 10 dimasukkan failure (F).8 orang meninggal.Kesimpulan.Acute kidney injuryterbanyak dijumpai pada laki-laki dengan kasus terbanyak termasuk kriteria injury(I).

scholarly journals IMPACT OF TIMING OF RENAL REPLACEMENT THERAPY INITIATION ON OUTCOME OF ACUTE KIDNEY INJURY IN SEPTIC PATIENTS

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S213-18
Author(s):  
Muhammad Nasir ◽  
Madiha Hashmi ◽  
Muhammad Sohaib ◽  
Zahoor Ahmed ◽  
Muhammad Salman ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Continuous Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Blood Urea Nitrogen ◽  
Kidney Injury ◽  
Urea Nitrogen ◽  
Therapy Initiation ◽  
Renal Replacement Therapy Initiation ◽  
Late Group

Objective: To identify whether the timing of initiation of continuous renal replacement therapy affects outcome in septic patients with acute kidney injury in term of 28 days mortality. Study Design: Cross sectional analytical study. Place and Duration of Study: This research was conducted at department of Anaesthesiology and critical careunit of the Aga Khan University Hospital, Karachi, from Oct 2018 to Jun 2019. Methodology: The study reviewed all adult patients aged >18 years who developed acute kidney injury afterseptic shock and required continuous renal replacement therapy in surgical intensive care unit. Considering thevalue of blood urea nitrogen, patients were classified into two groups. One was in early group that‟s was defined as blood urea nitrogen value of <100 mg/dl just before continuous renal replacement therapy initiation while the patients who have blood urea nitrogen value of ≥100 mg/dl just prior to continuous renal replacement therapy initiation were classified as late group. Kaplan-Meier survival analysis was performed and median survival was computed. Results: Forty patients were included for analysis. There were thirty patients (75%) in early group in whomcontinuous renal replacement therapy was started with mean blood urea nitrogen of 66 ± 20.2 mg/dL and 10(25%) patients were in late group with mean blood urea nitrogen of 137 ± 28.4 mg/dL. The overall survival ratesin both groups were 49.6%, and 10.4% at 10 and 25 days, respectively. Median survival time was not statisticallysignificant between early and late continuous renal replacement...........

Efficacy of Atorvastatin in Prevention of Contrast induced Nephropathy in Patients Undergoing Coronary Angiography

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ayman Mokhtar Kamaly ◽  
Ghada Mohamed Samir ◽  
Hany Magdy Fahim ◽  
Amira Mohamed Gaber Mahmoud
Keyword(s):  
Acute Kidney Injury ◽  
Coronary Angiography ◽  
Contrast Media ◽  
Significant Positive Correlation ◽  
Kidney Injury ◽  
Contrast Nephropathy ◽  
Positive Correlation ◽  
Radiocontrast Media ◽  
Total Prevalence ◽  
Significant Difference

Abstract Background The use of radiocontrast media has increased greatly from the past decades for diagnostic radiography and interventional procedures and it is estimated that approximately 60 million people in the world are used radiocontrast media each year. Objective The aim of this study was to evaluate the efficacy of atorvastatin (ATN) 80 mg in the prevention of CIN in patients undergoing angiography. Patients and Methods This study was a prospective, two‑arm, parallel group, controlled, clinical trial. This study has been performed on 100 Egyptian patients. Patients of either sex and aged between 21 and 65 years admitted for coronary angiography from January 2019 to June 2019, the patients had serum cretinine between 1 and 1.5 mg/dl or estimated glomerular filtration rate (eGFR &gt; 60 ml/min/1.73m2) and suffering from controlled DM or HTN. Results As regard to prevalence of contrast nephropathy, in our study we found that the total prevalence was 13%. We have concluded a great effect of diabetes on development of contrast nephropathy. We have concluded a great effect of hypertension on development of contrast nephropathy. There was a great effect of number of vessels affected on development of contrast nephropathy. As regard FBS there was no significant difference between the two groups. Also, there was a highly significant positive correlation between and study markers of acute kidney injury (72 h- Serum creat Delta Serum creat, 72 h- GFR and Delta GFR) and FBS. As regard Contrast media dose there was no significant difference between the two groups. Also, there was a highly significant positive correlation between and study markers of acute kidney injury (72 h- Serum creat Delta Serum creat, 72 h- GFR and Delta GFR) and contrast media dose. In our study there was a highly significant difference between the two groups as regard study markers of evidence of contrast nephropathy (72 h- Serum creat Delta Serum creat, 72 h- GFR and Delta GFR).Also, there was a great effect of on development of contrast nephropathy. In our study there was a highly significant difference between the two groups as regard study markers of evidence of contrast nephropathy (72 h- Serum creat Delta Serum creat, 72 h- GFR and Delta GFR).Also, there was a great effect of on development of contrast nephropathy. Conclusion There was a beneficial significant effect of statin on prevention of contrast nephropathy, also we concluded that age, hypertension, DM, dyslipidaemia, FBS, hemoglobin level, serum uric acid and dose of contrast media are major risk factors for developing contrast nephropathy.

scholarly journals The Chronic Kidney Disease and Acute Kidney Injury Involvement in COVID-19 Pandemic: A Systematic Review and Meta-analysis

2020 ◽  
Author(s):  
Ya-Fei Liu ◽  
Zhe Zhang ◽  
Xiao-Li Pan ◽  
Guo-Lan Xing ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Kidney Disease ◽  
Acute Kidney Injury ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Blood Urea Nitrogen ◽  
Meta Analysis ◽  
Kidney Injury ◽  
Urea Nitrogen ◽  
Severe Group

ABSTRACTAimThe aim of this study was to uncover whether kidney diseases were involved in COVID-19 pandemic from a systematic review.MethodsThe studies reported the kidney outcomes in different severity of COVID-19 were included in this study. Standardized mean differences or odds ratios were calculated by employing Review Manager meta-analysis software.ResultsThirty-six trials were included in this systematic review with a total of 6395 COVID-19 patients. The overall effects indicated that the comorbidity of chronic kidney disease (CKD) (OR = 3.28), complication of acute kidney injury (AKI) (OR = 11.02), serum creatinine (SMD = 0.68), abnormal serum creatinine (OR = 4.86), blood urea nitrogen (SMD = 1.95), abnormal blood urea nitrogen (OR = 6.53), received continuous renal replacement therapy (CRRT) (OR = 23.63) was significantly increased in severe group than that in nonsevere group. Additionally, the complication of AKI (OR = 13.92) and blood urea nitrogen (SMD = 1.18) were remarkably elevated in critical group than that in severe group.ConclusionCKD and AKI are susceptible to occur in patients with severe COVID-19. CRRT is applied frequently in severe COVID-19 patients than that in nonsevere COVID-19 patients. The risk of AKI is higher in critical group than that in severe group.

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