scholarly journals Radiation Dose Burden To The Thyroid Gland Following Postoperative Radiotherapy Of Breast Cancer: A Comparative Dosimetric Study

2012 ◽  
Vol 8 (Issue 1-2) ◽  
pp. 5-11
Author(s):  
Amr Sakr ◽  
Khaled Thabet ◽  
Wael Makar ◽  
Mohammed El-Sayed
Author(s):  
Sajeev George Pulickal ◽  
Nikhil Sebastian ◽  
Reshma Bhaskaran ◽  
P Aparna

Abstract Background and aim: Radiation exposure to the thyroid gland during breast irradiation can lead to hypothyroidism and this can impact on the quality of life. The aim of this study was to analyse if there is any difference in the radiation dose received by the thyroid gland during supraclavicular irradiation for breast cancer, with two different neck positions—straight or when the head is turned to the contralateral side to the breast being treated, when using a conformal technique. Materials and methods: All patients who received chest wall/breast and supraclavicular irradiation for breast cancer in 2019 in our department were divided into two groups based on the neck position as SN (neck positioned straight) and TN (neck tilted to contralateral side). The volume of thyroid gland, the radiation dose and volume parameters for Dmax, Dmean, and V5 to V40 of the thyroid were tabulated. Results: There were 72 patients included in the study with a mean age of 59 years, with 39 in the SN group and 33 in the TN group. There was no significant difference in thyroid volume between the two groups. Dmean, V15, V20, V25, V30 and V35 were significantly lower in tilted neck patients as compared to straight neck patients. Conclusion: Neck positioned to the contralateral side of the breast primary may be recommended for conformal CT-based radiation planning.


2015 ◽  
Vol 40 (3) ◽  
pp. 190-194 ◽  
Author(s):  
Jiahao Wang ◽  
Xiadong Li ◽  
Qinghua Deng ◽  
Bing Xia ◽  
Shixiu Wu ◽  
...  

1981 ◽  
Vol 20 (02) ◽  
pp. 72-75 ◽  
Author(s):  
R. Kocak ◽  
R.G. Herbert ◽  
C.R. Squire ◽  
T.M.D. Gimlette

Radioiodine in the thyroid gland after a therapy dose of 131I was measured serially in 7 patients without Carbimazole, and in 11 patients starting Carbimazole 60 mg daily fourteen days after the therapy dose. Effective half-life for radioiodine in the gland initially 5.53±1.08 days fell to 4.26±1.12 days (p < 0.01) during Carbimazole, and returned to 5.83±1.21 days (NS) after stopping the drug. The radiation dose to the thyroid from a given therapy dose of 131I followed by Carbimazole was calculated to be 97% of that without Carbimazole when the drug was started after 14 days, and 90% and 75% when the drug was started after 7 days and 1 day respectively.


2018 ◽  
Vol 127 ◽  
pp. S1005-S1006
Author(s):  
S. Stewart ◽  
S. Bowles ◽  
N. Macdougall ◽  
J. Conibear ◽  
V. Wolstenholme ◽  
...  

2014 ◽  
Vol 489 ◽  
pp. 012015 ◽  
Author(s):  
P Lonski ◽  
M L Taylor ◽  
W Hackworth ◽  
A Phipps ◽  
R D Franich ◽  
...  

2021 ◽  
Vol 100 (4) ◽  

Introduction: The purpose of this study was to compare the radiation dose to organs at risk for deep-inspiration breath hold (DIBH) and free-breathing (FB) radiotherapy in patients with lef-sided breast cancer undergoing adjuvant radiotherapy after partial mastectomy. Methods: One hundred patients with left-sided breast cancer underwent DIBH and FB planning computed tomography scans, and the 2 techniques were compared. Dose-volume histograms were analyzed for heart, left anterior descending coronary artery (LAD), and left lung. Results: Radiation dose to heart, LAD, and left lung was significantly lower for DIBH than for free breathing plans. The median mean heart dose for DIBH technique in comparison with FB was 1.21 Gy, and 3.22 Gy respectively; for LAD, 4.67 versus 24.71 Gy; and for left lung 8.32 Gy versus 9.99 Gy. Conclusion: DIBH is an effective technique to reduce cardiac and lung radiation exposure.


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