scholarly journals DIETARY Nigella sativa AND YEAST CELL WALL FOR REDUCING THE TOXICITY OF OCHRATOXIN A IN CULTURED NILE TILAPIA IN EGYPT.

2011 ◽  
Vol 2 (8) ◽  
pp. 327-336 ◽  
Author(s):  
Amel Abo Hagger ◽  
Kh. El-Melegy ◽  
Zeinab Abdel- Ghany ◽  
R. Abou-Seif
Toxins ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 37 ◽  
Author(s):  
Suvi Vartiainen ◽  
Alexandros Yiannikouris ◽  
Juha Apajalahti ◽  
Colm A. Moran

Ochratoxin A (OTA) is a common mycotoxin contaminant in animal feed. When absorbed from the gastrointestinal tract, OTA has a propensity for pathological effects on animal health and deposition in animal tissues. In this study, the potential of yeast cell wall extracts (YCWE) to adsorb OTA was evaluated using an in vitro method in which consecutive animal digestion events were simulated. Low pH markedly increased OTA binding to YCWE, which was reversed with a pH increased to 6.5. Overall, in vitro analysis revealed that 30% of OTA was adsorbed to YCWE. Additional computational molecular modelling revealed that change in pH alters the OTA charge and modulates the interaction with the YCWE β-d-glucans. The effectiveness of YCWE was tested in a 14-day broiler chicken trial. Birds were subjected to five dietary treatments; with and without OTA, and OTA combined with YCWE at three dosages. At the end of the trial, liver OTA deposition was evaluated. Data showed a decrease of up to 30% in OTA deposits in the liver of broilers fed both OTA and YCWE. In the case of OTA, a tight correlation between the mitigation efficacy of YCWE between in vitro and in vivo model could be observed.


2018 ◽  
Vol 12 (2) ◽  
pp. 7-13 ◽  
Author(s):  
Damoon Ghofrani Tabari ◽  
Hassan Kermanshahi ◽  
Abolghasem Golian ◽  
Reza Majidzadeh Heravi ◽  
◽  
...  

2005 ◽  
Vol 40 (9) ◽  
pp. 3008-3016 ◽  
Author(s):  
Diana Ringot ◽  
Benoit Lerzy ◽  
Jean Paul Bonhoure ◽  
Eric Auclair ◽  
Eric Oriol ◽  
...  

2010 ◽  
Vol 27 (8) ◽  
pp. 1153-1160 ◽  
Author(s):  
S. Firmin ◽  
P. Gandia ◽  
D.P. Morgavi ◽  
G. Houin ◽  
J.P. Jouany ◽  
...  

2018 ◽  
Vol 44 (4) ◽  
pp. 333-341 ◽  
Author(s):  
Nermeen M. Abu-Elala ◽  
Nehal A. Younis ◽  
Huda O. AbuBakr ◽  
Naela M. Ragaa ◽  
Liliana L. Borges ◽  
...  

2011 ◽  
Vol 74 (7) ◽  
pp. 1175-1185 ◽  
Author(s):  
CLAIRE JOANNIS-CASSAN ◽  
MARIANA TOZLOVANU ◽  
KHEIRA HADJEBA-MEDJDOUB ◽  
NATHALIE BALLET ◽  
ANNIE PFOHL-LESZKOWICZ

A methodology was developed to quantify the efficiency of yeast-based products for adsorption of three mycotoxins: zearalenone (ZEA), aflatoxin B1 (AFB1), and ochratoxin A (OTA). Eight products were tested (yeast cell wall or inactivated yeast). The described experimental protocol based on in vitro tests provided reliable isotherms for each mycotoxin. The most suitable models were the Hill model for ZEA, the Langmuir model for AFB1, and the Freundlich model for OTA. From these models, original mathematical affinity criteria were defined to quantify the product adsorption performances for each mycotoxin. The best yeast product, a yeast cell wall from baker's yeast, can adsorb up to 68% of ZEA, 29% of AFB1, and 62% of OTA, depending on the mycotoxin concentrations. The adsorption capacity largely depended both on yeast composition and mycotoxin, but no direct correlation between yeast composition and adsorption capacity was found, confirming that adsorption of mycotoxin on yeast-based products involves complex phenomena. The results of this study are useful for comparing the adsorption efficiency of various yeast products and understanding the mechanisms involved in adsorption.


Author(s):  
Giulia Maria Pires dos Santos ◽  
Gustavo Ramalho Cardoso dos Santos ◽  
Mariana Ingrid Dutra da Silva Xisto ◽  
Rodrigo Rollin-Pinheiro ◽  
Andréa Regina de Souza Baptista ◽  
...  

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